MammaPrint(R) Breast Cancer Test Shown To Be Powerful Tool for Prognosis Prediction in Postmenopausal Breast Cance... (r low or high riskfor distant metastasis...)

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MammaPrint(R) Breast Cancer Test Shown To Be Powerful Tool for Prognosis Prediction in Postmenopausal Breast Cancer Patients

Date:12/17/2007

r low or high risk for distant metastasis and the results were compared to actual outcome of disease in these patients. The results of the study confirm that MammaPrint is also a very powerful tool to identify older breast cancer patients at low risk for metastatic disease. The results of this study have been submitted for publication to one of the major clinical research journals.

"We are very pleased with this new validation study," says Bernhard Sixt, chief executive officer (CEO) of Agendia. "MammaPrint is now independently validated for both premenopausal and postmenopausal women, an important and necessary validation considering that breast cancer biology between the two groups is different. We are confident that we now have enough data to seek clearance from the FDA for use of this test in breast cancer patients of all ages."

About MammaPrint(R)

MammaPrint(R) laboratory service is the first and only FDA cleared (February 2007) DNA microarray-based 'in vitro diagnostic multivariate index assay' (IVDMIA). MammaPrint measures the activity of 70 genes, providing information about the likelihood of tumor recurrence. The MammaPrint test measures the level of expression of each of these genes in a sample of a woman's surgically-removed breast cancer tumor and then uses a specific formula or algorithm to produce a score that determines whether the patient is deemed low risk or high risk for spread of the cancer to another site. The result may help a doctor in planning treatment and appropriate follow-up for a patient when used with other clinical information and laboratory tests. All MammaPrint tests are conducted in Agendia's CLIA-Certified central service laboratory.

About Agendia

Agendia, located in Amsterdam, The Netherlands, is a world leader in gene expression analysis-based diagnostics with three products on the market. The company focuses on the development and commercialization of diagnostic tests using tumor gene expressio
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SOURCE Agendia BV
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MammaPrint(R) Breast Cancer Test Shown To Be Powerful Tool for Prognosis Prediction in Postmenopausal Breast Cance...(r low or high riskfor distant metastasis...),Health