Navigation Links
Malnutrition decreases effectiveness of HIV treatment in pregnant African women

In Uganda the prescription of three antiretroviral (ARV) drugs, which aim to suppress the virus to prevent disease progression, have resulted in huge reductions in HIV mortality rates. However, disease is not the only scourge in Uganda, and a new study in The Journal of Clinical Pharmacology explores the impact food insecurity may have on treating pregnant women.

A U.S-Ugandan research team explored the affect pregnancy and malnutrition can have on the administration of lopinavir/ritonavir (LPV/r) and efavirenz (EFV) drugs among HIV-infected women in Tororo, Uganda.

Blood and hair samples from 221 women were analyzed, revealing that 80% of patients were malnourished and 26% lost weight during their pregnancy. Average (median) Body Mass Index was found to be only 20.2 kg/m2.

The team found that, compared to well-nourished patients, drug exposure was reduced in these patients (LPV −33%, EFV −15%, ritonavir −17%).

"This study in 221 pregnant and breastfeeding HIV-infected women with severe food insecurity in Uganda showed that food insecurity influences exposure parameters to antiretroviral treatment," said Dr. Imke Bartelink. "Compared to previously published data from well-nourished women, food insecurity is associated with decreases in antiretroviral exposure ranging from 15% to 41% in this group of pregnant and breastfeeding women, irrespective of pregnancy status."

Contact: Ben Norman

Page: 1

Related medicine news :

1. Researchers at St. Michaels Hospital test tool for screening cancer patients for malnutrition
2. Vitamin D decreases pain in women with type 2 diabetes and depression
3. Weight reduction decreases atrial fibrillation and symptom severity
4. Clearwater, FL Laser Gum Surgery Decreases Bleeding Gums and Gum Disease Risks for Expecting Mothers with Gum Disease through Dr. Stephen Kobernick
5. Music decreases perceived pain for kids in pediatric ER: UAlberta medical research
6. Removal of tumor-associated immune cell protein decreases tumor progression
7. Preemptive treatment of severe morning sickness decreases suffering for moms-to-be
8. Mexican paradox: While opinion surveys overestimate abortions 10-fold, abortion mortality clearly decreases
9. Teen smoking decreases bone accumulation in girls, may increase osteoporosis risk
10. 24-hour ICU in-house staff intensivist improves mortality and decreases length of stay
11. Increasing dopamine in brains frontal cortex decreases impulsive tendency, UCSF-Gallo study finds
Post Your Comments:
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... Austin ... of the American College of Mohs Surgery and to Dr. Russell Peckham for medical ... and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency ... named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. ... Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van ... Wellness at Work award to iHire in recognition of their exemplary accomplishments in worksite ... 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum ...
(Date:6/24/2016)... Marne, Michigan (PRWEB) , ... June 24, 2016 , ... ... To deal with these feelings, many turn to unhealthy avenues, such as drug or ... Center of Marne, Michigan, has released tools for healthy coping following a traumatic event. ...
(Date:6/24/2016)... ... 24, 2016 , ... The Pulmonary Hypertension Association (PHA) learned ... receive two significant new grants to support its work to advance research and ... by recognizing patients, medical professionals and scientists for their work in fighting pulmonary ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Mass. and SAN CLEMENTE, Calif. , ... California -based mobile pulmonary function testing company, is now able ... PFT devices developed by ndd Medical Technologies , Inc. ... testing done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® ... , can get any needed testing done in the comfort ...
(Date:6/24/2016)... , June 24, 2016 VolitionRx ... of Dr. Edward Futcher to the ... effective June 23, 2016.Dr. Futcher was also appointed ... Governance Committees.  As a non-executive member of the ... and strategic counsel to VolitionRx in connection with ...
(Date:6/23/2016)... , June 23, 2016 Any dentist who ... challenges of the current process. Many of them do not ... the technical difficulties and high laboratory costs involved. And those ... offer it at such a high cost that the majority ... Dr. Parsa Zadeh , founder of Dental ...
Breaking Medicine Technology: