Navigation Links
Male smokers less likely to need joint replacement surgery of hip or knee
Date:7/7/2011

Surprising results from a new study revealed that men who smoke had less risk of undergoing total joint replacement surgery than those who never smoked. Researchers also reported that men who were overweight, or who engaged in vigorous physical activity were more likely to need arthroplasty. Details of this study are now available in Arthritis & Rheumatism,a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR).

Research has shown that total hip and knee replacements, also known as arthroplasty, are among the most common elective surgeries performed in developed countries. According to data from the 2007 National Hospital Discharge Survey an estimated 230,000 Americans had hip replacement surgery and 543,000 received knee replacements, with severe osteoarthritis (OA) cited as the most frequent cause for undergoing the procedure. OAthe most common form of arthritiscauses pain and stiffness in the joints, with studies indicating that older age, female gender, and obesity increase disease risk.

In the current study, George Mnatzaganian, a PhD student from the University of Adelaide in Australia, and colleagues examined the associations of smoking, body mass index (BMI), and physical activity as they relate to risk of joint replacement surgery in men. Clinical data for the 11,388 male study participants, who were part of the Health in Men Study (HIMS), were integrated with hospital morbidity data and mortality records. During the initial health screening (1996-1999), HIMS subjects were surveyed regarding smoking history and physical activity.

Researchers analyzed clinical data from baseline through March 2007, identifying 857 men who had joint replacement surgery following the screening. Of those having surgery, 59% had total knee replacement and 41% had total hip replacement. Subjects were categorized into three age groups: 65-69 years, 70-74 years, and 75 or more years of age.

Analysis showed that being overweight independently increased total joint replacement risk, while smoking lowered the risk, which was most evident after 23 years of smoking exposure. In fact, men who smoked 48 years or more were up to 51% less likely to undergo total joint replacements than those who never smoked. The team also reported that vigorous exercise increased risk of joint replacement in men in the 70-74 year age group.

"Our study is the first to demonstrate a strong inverse correlation between smoking duration and risk of total joint replacement. The independent inverse associations of smoking with risk of total joint replacement were evident also after adjusting for major confounders and after accounting for the competing mortality risk in this elderly cohort of men," Mnatzaganian confirmed. "Further investigation is needed to determine how smoking impacts the development of OA."


'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. Nicotine replacement therapy is over-promoted since most ex-smokers quit unassisted
2. Genetic variant greatly increases lung cancer risk for light smokers
3. Longtime Smokers May Find Protection From Parkinsons
4. Blood Vessels Bounce Back Once Smokers Quit
5. Gene is linked to lung cancer development in never-smokers
6. Gene Linked to Lung Cancer Risk in Non-Smokers
7. Movies Trigger Young Adult Smokers to Light Up
8. Researchers discover new approach for identifying smokers at highest risk for developing lung cancer
9. Arteries Age Twice as Fast in Smokers
10. Alcohol consumption may protect against risk of AD, particularly in female nonsmokers
11. Women Smokers Targeted on World No Tobacco Day
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... February 12, 2016 , ... Fixed Dose Combination Drug ... p.m. EST, http://www.fdanews.com/fixeddosecombination , Fixed dose combination products ... increased attention from all stakeholders in the development of new chemical entities. , ...
(Date:2/12/2016)... , ... February 12, 2016 , ... ... Leadership Series at Zuckerberg San Francisco General Hospital on April 5-7. The series ... behaviors and create new habits. The workshops cover a broad range of topics, ...
(Date:2/12/2016)... , ... February 12, 2016 , ... The Jones Agency, ... communities across eastern Texas, is launching a cooperative charity drive with the Tarrant Area ... Serving more than 50,000 individuals and families in need, the Tarrant County Food Bank ...
(Date:2/12/2016)... ... ... Miami Dental Specialists is excited to bring patients the choice of ceramic, ... Dental Specialists will offer the non-metal implants as a safe, holistic and hygienic approach ... the dental implant manufacturer, Straumann, to bring this cutting-edge technology to Miami. ...
(Date:2/12/2016)... ... 2016 , ... Atlantic Information Services, Inc. (AIS) is pleased ... upcoming Feb. 24 webinar that will discuss ways health plans and PBMs are ... the $1,000-per-pill hepatitis C treatment Sovaldi and high-cost PCSK9 inhibitors to treat cholesterol. ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... Calif. , Feb. 12, 2016  SI-BONE, Inc., a medical ... ® ("iFuse"), a minimally invasive surgical (MIS) device indicated for ... National Government Services, Inc. (NGS), the Medicare Administrative Contractor (MAC) covering ... , Maine , Massachusetts ... , New York , Rhode Island ...
(Date:2/12/2016)... Calif. , Feb. 12, 2016  Sequent Medical, ... in a study to evaluate the safety and effectiveness ... the treatment of ruptured intracranial aneurysms.  Prof Laurent ... Hospital, in Paris, France and ... patient. France and Germany.  ...
(Date:2/12/2016)... Lilly and Company (NYSE: LLY ) today announced that ... regimen patent would not presently be infringed by Actavis marketing ... Italy and Spain ... solution.  --> --> ... that Lilly,s patent would be indirectly infringed by Actavis marketing ...
Breaking Medicine Technology: