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Male infertility linked to mortality in study led by Stanford researcher
Date:5/15/2014

at the moment and in mental shape to be planning for your future," Eisenberg said. In fact, the men seen at the two medical centers both those with and those without semen abnormalities tended to die at slower rates than the general U.S. male population.

Nevertheless, within this select group, the difference in death rates between those who had semen abnormalities and those who didn't was statistically significant. Those with two or more semen abnormalities were more than twice as likely to die during the follow-up period as those without any. This difference remained despite the investigators' efforts to control, where possible, for baseline health differences between the two sets of patients. They corrected for age and known diseases.

"It's plausible that, even though we didn't detect it, infertility may be caused by pre-existing general health problems," Eisenberg said. The true cause of increased mortality risk, then, would be not infertility per se, but those health problems.

"But we controlled for this factor as best we could, and while that did attenuate the measured risk somewhat, there seems to be something else going on. Could it be genetic, developmental or hormonal factors? Or could it be that something about the experience of having and raising kids even though you may sometimes feel like they're killing you actually lowers mortality?"

Eisenberg and his associates are trying to figure out why this is happening. "Is their blood pressure rising? What about their blood sugar, or other measures? We are starting to do prospective data collections now, through a collaboration involving several centers in the United States and Canada," he said.


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Contact: Bruce Goldman
goldmanb@stanford.edu
650-725-2106
Stanford University Medical Center
Source:Eurekalert

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