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Male infertility linked to mortality in study led by Stanford researcher
Date:5/15/2014

in the National Death Index and the Social Security Death index, the investigators were able to monitor these men's mortality for a median of about eight years. "We were able to determine with better than 90 percent accuracy who died during that follow-up time," Eisenberg said. "There was an inverse relationship. In the years following their evaluation, men with poor semen quality had more than double the mortality rate of those who didn't."

While no single semen abnormality in itself predicted mortality, men with two or more such abnormalities had more than double the risk of death over the eight-year period following their initial fertility examination compared with those with no semen abnormalities. The greater the number of abnormalities, the higher the mortality rate, the study found.

"Eisenberg and colleagues provide empirical evidence in support of the evolving literature suggesting that human fecundity influences health and disease across the life span," Germaine Buck Louis, PhD, director of the division of intramural population health research at the Eunice Kennedy Shriver National Institute of Child Health and Human Development, wrote in an accompanying editorial, "Male fecundity and its implications of health and disease across the lifespan," in Human Reproduction. "Human fecundity may be both informative and predictive about continual health status and later-onset disease."

Of the 11,935 men who were followed, 69 died during the follow-up period a seemingly small number. This reflects, first and foremost, the patients' relative youth: Their median age was 36.6 years. But it also reflects the fact that men who get evaluated for infertility tend to have a higher-than-average socio-economic status and have accordingly better diets, education and access to health care.

Moreover, men who are concerned about infertility are men who want to have children. "If you're trying to have a child, you're probably reasonably healthy
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Contact: Bruce Goldman
goldmanb@stanford.edu
650-725-2106
Stanford University Medical Center
Source:Eurekalert

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