Navigation Links
Male infertility associated with testicular cancer
Date:2/23/2009

Men who are infertile appear to have an increased risk of developing testicular cancer, according to a report in the February 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Testicular germ cell cancer, the most common cancer among young men in industrialized countries, has become even more prevalent during the last 30 to 50 years, according to background information in the article. There is evidence that semen quality and male fertility have also declined during this time in industrialized nations; however, it is unclear whether these two trends are related.

Thomas J. Walsh, M.D., M.S., then of the University of California, San Francisco, and now of the University of Washington School of Medicine, Seattle, and colleagues analyzed data from 22,562 male partners of couples seeking fertility treatment between 1967 and 1998 (4,549 of whom had male factor infertility, based on a clinical presentation with abnormal semen analysis criteria). Their records were linked to the state cancer registry, which includes information about cancer cases confirmed between 1988 and 2004.

A total of 34 of the 22,562 men were diagnosed with testicular cancer at least one year after seeking treatment for infertility. Compared with men of the same age in the general populationwhose records were identified using the National Cancer Institute's Surveillance Epidemiology and End Results programmen in couples seeking treatment for infertility were 1.3 times more likely to develop testicular cancer. Men with male factor infertility were 2.8 more likely to develop testicular cancer than those without this condition.

"In interpreting these data, we considered the postulate that male factor infertility or its treatment could cause testicular cancer," the authors write. "However, this theory is highly improbable given that in many cases infertility treatment involves the use of assisted reproductive technologies rather than specific medical or surgical treatment of the male partner." It is also unlikely that the results representing a screening phenomenon, in which men who seek treatment for infertility are diagnosed with a previously unrecognized cancer because of diagnostic testing. Most cases of testicular cancer in adults are diagnosed rapidly when a physical exam reveals a nodule or swelling in the scrotum.

"A more plausible explanation is that a common exposure underlies infertility and testicular cancer," the authors conclude. Faulty DNA repair, or errors in the way the body responds to small areas of damage in its genetic material, may contribute to both conditions, as may environmental factors.


'/>"/>

Contact: Mary Guiden
mguiden@u.washington.edu
206-616-3192
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Male Infertility Tied to Testicular Cancer Risk
2. Household chemicals may be linked to infertility
3. Local Infertility Specialist, Dr. Rachel Bennett, Westchester Reproductive Medicine, Opens New Office in Mount Kisco
4. The AFAs Infertility Prevention Series Premieres in NYC
5. Free Early Education Program to Lower Infertility Rates
6. Women Unhappy With Disposal Options After Infertility Treatment
7. Infertility Survivor Creates Symbolic Pendant to Honor the Journey.
8. Assisted Fertilization Risks May Be Due to Infertility
9. Diabetes, Weight Tied to Male Infertility
10. Fathers Age a Factor in Infertility
11. New photo op for ovaries may solve some mysteries of infertility
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/17/2017)... ... January 17, 2017 , ... The Sharie Withers ... has announced the latest beneficiary of their thriving community involvement program. The current ... to fulfilling the dreams of terminally ill patients. Donations to this worthy cause ...
(Date:1/17/2017)... ... January 17, 2017 , ... Many people make New Year’s resolutions or renew their ... is making it easier for people who want to kick off 2017 with better ... existing patients. , These special offers include: , , A ...
(Date:1/17/2017)... ... 17, 2017 , ... Twelve (12) years ago the Yogi ... program forged a relationship built upon the foundation of sports safety. Recently, ... both student members and certified members of the Athletic Trainers’ Society of New ...
(Date:1/16/2017)... ... January 17, 2017 , ... Recently, patients and staff ... Michigan, joined other volunteers and organizations in support of the annual Binder Park Zoo ... families dressed up in colorful costumes of all designs coming out to enjoy games, ...
(Date:1/16/2017)... ... 2017 , ... Gym Source, America’s leading retailer of premium residential and commercial ... Jersey. , “We are elated to be opening this new showroom,” explains Tom Richard, ... give clients a seamless and motivating shopping experience.” , Every fitness journey is unique, ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... Interpace Diagnostics Group, Inc., (NASDAQ: IDXG ... tests and pathology services for evaluating risks of cancer, ... January 13, 2017 from the NASDAQ Listing Qualifications notifying ... requirement of the NASDAQ Stock Market to maintain a ... The letter noted that for the last 10 ...
(Date:1/17/2017)... Jan. 17, 2017 Tempus, a technology ... and University Hospitals Seidman Cancer Center have joined ... genomic data, advanced molecular analysis and clinical decision ... and healthcare providers. As part ... and transcriptomic sequencing and analysis for ovarian and ...
(Date:1/17/2017)... , Jan. 17, 2017  CSSi, the global ... the clinical research industry, will exhibit at the 8 ... Executives (SCOPE 2017), taking place from Tuesday, January 24 ... Miami in Miami, FL. ... proprietary technology platform, SmartStudy™ EMR, which provides a revolutionary ...
Breaking Medicine Technology: