Navigation Links
Male infertility associated with testicular cancer
Date:2/23/2009

Men who are infertile appear to have an increased risk of developing testicular cancer, according to a report in the February 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Testicular germ cell cancer, the most common cancer among young men in industrialized countries, has become even more prevalent during the last 30 to 50 years, according to background information in the article. There is evidence that semen quality and male fertility have also declined during this time in industrialized nations; however, it is unclear whether these two trends are related.

Thomas J. Walsh, M.D., M.S., then of the University of California, San Francisco, and now of the University of Washington School of Medicine, Seattle, and colleagues analyzed data from 22,562 male partners of couples seeking fertility treatment between 1967 and 1998 (4,549 of whom had male factor infertility, based on a clinical presentation with abnormal semen analysis criteria). Their records were linked to the state cancer registry, which includes information about cancer cases confirmed between 1988 and 2004.

A total of 34 of the 22,562 men were diagnosed with testicular cancer at least one year after seeking treatment for infertility. Compared with men of the same age in the general populationwhose records were identified using the National Cancer Institute's Surveillance Epidemiology and End Results programmen in couples seeking treatment for infertility were 1.3 times more likely to develop testicular cancer. Men with male factor infertility were 2.8 more likely to develop testicular cancer than those without this condition.

"In interpreting these data, we considered the postulate that male factor infertility or its treatment could cause testicular cancer," the authors write. "However, this theory is highly improbable given that in many cases infertility treatment involves the use of assisted reproductive technologies rather than specific medical or surgical treatment of the male partner." It is also unlikely that the results representing a screening phenomenon, in which men who seek treatment for infertility are diagnosed with a previously unrecognized cancer because of diagnostic testing. Most cases of testicular cancer in adults are diagnosed rapidly when a physical exam reveals a nodule or swelling in the scrotum.

"A more plausible explanation is that a common exposure underlies infertility and testicular cancer," the authors conclude. Faulty DNA repair, or errors in the way the body responds to small areas of damage in its genetic material, may contribute to both conditions, as may environmental factors.


'/>"/>

Contact: Mary Guiden
mguiden@u.washington.edu
206-616-3192
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Male Infertility Tied to Testicular Cancer Risk
2. Household chemicals may be linked to infertility
3. Local Infertility Specialist, Dr. Rachel Bennett, Westchester Reproductive Medicine, Opens New Office in Mount Kisco
4. The AFAs Infertility Prevention Series Premieres in NYC
5. Free Early Education Program to Lower Infertility Rates
6. Women Unhappy With Disposal Options After Infertility Treatment
7. Infertility Survivor Creates Symbolic Pendant to Honor the Journey.
8. Assisted Fertilization Risks May Be Due to Infertility
9. Diabetes, Weight Tied to Male Infertility
10. Fathers Age a Factor in Infertility
11. New photo op for ovaries may solve some mysteries of infertility
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping to ... app. The fitness app plans to fix the two major problems leading the fitness industry ... fits all type program , They don’t eliminate all the reasons people quit ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery ... of Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , ... for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey ...
(Date:6/25/2016)... ... 25, 2016 , ... First Choice Emergency Room , the largest network ... the Medical Director of its new Mesquite-Samuell Farm facility. , “We are pleased ... location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... On Friday, ... presented a Bronze Wellness at Work award to iHire in recognition of their exemplary ... part of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI ...
(Date:6/24/2016)... ... 24, 2016 , ... Those who have experienced traumatic events may suffer from ... avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid this ... coping following a traumatic event. , Trauma sufferers tend to feel a range of ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 26, 2016 Story Highlights: ... models within the health care industry is causing providers ... , Deloitte offers a suite of solutions for ... impacting efficient cost optimization: labor resource analysis, revenue cycle ... facilitate better outcomes and better economics ...
(Date:6/24/2016)... 24, 2016 ... the addition of the " Global Markets for ... This report focuses on ... updated review, including its applications in various applications. The ... which includes three main industries: pharmaceutical and biotechnology, food ...
(Date:6/24/2016)... Research and Markets has announced the addition of ... report to their offering. ... The World Market for Companion Diagnostics covers the world market ... the report includes the following: , World ... Region (N. America, EU, ROW), 2015-2020 , World IVD ...
Breaking Medicine Technology: