Navigation Links
Male infertility associated with testicular cancer

Men who are infertile appear to have an increased risk of developing testicular cancer, according to a report in the February 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Testicular germ cell cancer, the most common cancer among young men in industrialized countries, has become even more prevalent during the last 30 to 50 years, according to background information in the article. There is evidence that semen quality and male fertility have also declined during this time in industrialized nations; however, it is unclear whether these two trends are related.

Thomas J. Walsh, M.D., M.S., then of the University of California, San Francisco, and now of the University of Washington School of Medicine, Seattle, and colleagues analyzed data from 22,562 male partners of couples seeking fertility treatment between 1967 and 1998 (4,549 of whom had male factor infertility, based on a clinical presentation with abnormal semen analysis criteria). Their records were linked to the state cancer registry, which includes information about cancer cases confirmed between 1988 and 2004.

A total of 34 of the 22,562 men were diagnosed with testicular cancer at least one year after seeking treatment for infertility. Compared with men of the same age in the general populationwhose records were identified using the National Cancer Institute's Surveillance Epidemiology and End Results programmen in couples seeking treatment for infertility were 1.3 times more likely to develop testicular cancer. Men with male factor infertility were 2.8 more likely to develop testicular cancer than those without this condition.

"In interpreting these data, we considered the postulate that male factor infertility or its treatment could cause testicular cancer," the authors write. "However, this theory is highly improbable given that in many cases infertility treatment involves the use of assisted reproductive technologies rather than specific medical or surgical treatment of the male partner." It is also unlikely that the results representing a screening phenomenon, in which men who seek treatment for infertility are diagnosed with a previously unrecognized cancer because of diagnostic testing. Most cases of testicular cancer in adults are diagnosed rapidly when a physical exam reveals a nodule or swelling in the scrotum.

"A more plausible explanation is that a common exposure underlies infertility and testicular cancer," the authors conclude. Faulty DNA repair, or errors in the way the body responds to small areas of damage in its genetic material, may contribute to both conditions, as may environmental factors.


Contact: Mary Guiden
JAMA and Archives Journals

Related medicine news :

1. Male Infertility Tied to Testicular Cancer Risk
2. Household chemicals may be linked to infertility
3. Local Infertility Specialist, Dr. Rachel Bennett, Westchester Reproductive Medicine, Opens New Office in Mount Kisco
4. The AFAs Infertility Prevention Series Premieres in NYC
5. Free Early Education Program to Lower Infertility Rates
6. Women Unhappy With Disposal Options After Infertility Treatment
7. Infertility Survivor Creates Symbolic Pendant to Honor the Journey.
8. Assisted Fertilization Risks May Be Due to Infertility
9. Diabetes, Weight Tied to Male Infertility
10. Fathers Age a Factor in Infertility
11. New photo op for ovaries may solve some mysteries of infertility
Post Your Comments:
(Date:12/1/2015)... ... December 01, 2015 , ... Florida Hospital Tampa is the first health care provider ... state of Florida. , vBloc® Therapy is a vagal blocking therapy, delivered via the Maestro® ... body mass index (BMI) of at least 40 to 45 kg, or a BMI of ...
(Date:12/1/2015)... ... December 01, 2015 , ... Dr. Paul Vitenas, one ... Surgery, has been named by MedEsthetics magazine as the Best Single Physician Practice in ... among the many elite aesthetic physicians honored by the industry publication. , Dr. ...
(Date:12/1/2015)... Delaware (PRWEB) , ... December 01, 2015 , ... ... winner at the 7th Annual 2015 Golden Bridge Business Awards under the New ... is a zero capex web based sample management software that helps ...
(Date:12/1/2015)... , ... December 01, 2015 , ... ... radiographic technicians must mark the film for accurate interpretation by the radiologist. The ... Fortunately, an inventor from Sacramento, Calif., has found a way to alleviate this ...
(Date:12/1/2015)... ... December 01, 2015 , ... ... it has been awarded a fixed price per sprint agile development contract to ... at $34 million over five years, provides software engineering, infrastructure, as well as ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... Dec. 1, 2015 WellStar Health System has ... Texas -based Tenet Healthcare,s five metro ... approved the strategic move following the conclusion of the ... clinical care models and patient safety programs that have ... to new communities. --> ...
(Date:12/1/2015)... , Dec. 1, 2015  Eyeon Therapeutics has ... dry eye treatments based on a charged hydrophilic ... delivery CDMO.  The product has been shown to ... previously published.  Mark Mitchnick , MD, CEO ... protection to additional polymers in conjunction with a ...
(Date:12/1/2015)... 1, 2015 Pharma Tech Outlook recently conducted ... Clinical Data Management Solution Providers - 2015 .  After ... comprising CEOs, CIOs, VCs, analysts, and the Pharma Tech ... of top 10 clinical data management solution providers (check ... 14 and 36 respectively). --> ...
Breaking Medicine Technology: