Navigation Links
Male circumcision lowers prevalence of penile precancerous lesions among African men
Date:7/28/2011

CHAPEL HILL, N.C. - A University of North Carolina-led international study shows that among Kenyan men, circumcision is associated with a lower prevalence of human papillomavirus-associated precancerous lesions of the penis. Human papillomavirus - HPV - is a sexually transmitted virus that plays an important role in genital cancers in men and women, including cancers of the penis and cervix.

Jennifer Smith, PhD, senior author, says, "Our data are the first to show that male circumcision may reduce HPV-associated penile precancerous lesions. This represents an additional public health benefit of male circumcision."

Smith is associate professor of epidemiology in the UNC Gillings School of Global Public Health and a member of UNC Lineberger Comprehensive Cancer Center.

The study was published as an online manuscript in May 2011 in the International Journal of Cancer.

Smith explains, "The percentage of men with HPV-associated precancerous penile lesions was substantially higher among those who were not circumcised 26 percent- compared to those who were circumcised - .7 percent."

She adds, "Interventions that reduce HPV-associated penile lesions could be important to both men and women, because such lesions may increase HPV transmission from men to their sexual partners.

"Circumcision may also provide a useful intervention to prevent HPV-associated penile lesions and ultimately invasive cervical cancers in less developed countries, since prophylactic HPV vaccines may not be readily available to men, and current HPV vaccines do not include protection against all high-risk HPV types."

The study was part of a larger trial undertaken to determine the effectiveness of male circumcision in reducing HIV incidence conducted by Robert Bailey, PhD with the University of Illinois at Chicago. In the UNC-led study, 275 men participated: 151 who were circumcised and 124 who were not. The protocol included a visual inspection of the penis to identify lesions and photographs that were read independently by two observers as well as a sample of penile exfoliated cells that were tested for HPV infection.


'/>"/>

Contact: Dianne Shaw
dgs@med.unc.edu
919-966-7834
University of North Carolina School of Medicine
Source:Eurekalert

Related medicine news :

1. Circumcision Helps Cut HPV Transmission Rate, Study Finds
2. New report provides womens perspectives on medical male circumcision for HIV prevention
3. Children's Rights Group Agrees with New Study: Infant Circumcision Causes 100 Deaths Each Year in US
4. Neonatal and infant circumcision: Safe in the right hands
5. Bettering Social Status Lowers High Blood Pressure Risk
6. Good Sleep Raises Quality of Life, Lowers Depression
7. Vytorin Lowers Heart Disease Risk in Large Study of Kidney Patients
8. Forecast calls for nanoflowers to help return eyesight
9. Case study reports singing lowers patients blood pressure prior to surgery
10. Better Cleaning in ICUs Lowers MRSA Infection Rates
11. New mode of dementia care improves health, lowers hospitalization rates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2017)... ... September 22, 2017 , ... TopConsumerReviews.com ... by Native Remedies that helps promote pancreatic health and regulate blood sugar ... some prescription-based approaches can have negative side effects, and with the changes in ...
(Date:9/22/2017)... , ... September 22, 2017 , ... “Letters From Home”: ... people, even the lost, have value to God. “Letters From Home” is the creation ... a member of the President’s Cabinet of Jerry Savelle Ministries International, who has traveled ...
(Date:9/21/2017)... ... September 21, 2017 , ... 38-Year-Old Plastic Surgeon Gill at Aesthetic Surgery ... is pleased to announce that Plastic Surgeon Kiranjeet Gill has been awarded as one ... is an annual award that was started in 2003 to salute young achievers in ...
(Date:9/21/2017)... ... September 21, 2017 , ... ... of a new member survey conducted by the International Society of Hair ... from 2014 to 2016 rose 60 percent, with 635,189 procedures performed in 2016. ...
(Date:9/21/2017)... ... September 21, 2017 , ... The New England Center for Children® ... the election of Yie-Hsin Hung to the Board of Directors. , “The New ... Directors. Ms. Hung is an invaluable addition to our team,” said Vincent Strully, Jr., ...
Breaking Medicine News(10 mins):
(Date:9/5/2017)... -- Oramed Pharmaceuticals Inc. (NASDAQ: ORMP ) ... focused on the development of oral drug delivery systems, ... with the U.S. Food and Drug Administration (FDA) regarding ... At the meeting, the FDA ... of ORMD-0801, would be a Biologics License Application (BLA).  ...
(Date:9/1/2017)... WHIPPANY, N.J. , Sept. 1, 2017  Bayer will ... at the European Society for Medical Oncology (ESMO) 2017 Congress, ... studies presented will include new preclinical and clinical data on ... from two earlier pipeline projects. ... of the best minds in cancer research at ESMO," said ...
(Date:8/29/2017)... RANDOLPH, N.J. , Aug. 29, 2017 ... inventory management, security, and regulatory compliance for veterinary practices ... today announced a new partnership that makes TITAN,s expertise ... legal compliance available to Cubex,s clients nationally. ... healthcare provider buying and handling controlled substances is at ...
Breaking Medicine Technology: