Navigation Links
Male cancer survivor offspring slightly higher risk of congenital birth abnormalities
Date:2/8/2011

The incidence of major congenital birth abnormalities was slightly higher in the offspring of male cancer survivors compared with children of fathers with no history of cancer, according to a study published online February 8th in the Journal of the National Cancer Institute.

The increasing number of male cancer survivors has given rise to concerns about the health of their offspring. Although previous studies on children conceived naturally have been reassuring about the health of the children, very few studies have looked at results among children conceived through assisted reproductive technologies (ARTs) such as in vitro fertilization or intracytoplasmatic sperm injection.

To determine the effects of paternal cancer and ARTs on pregnancy outcomes, O. Sthl, M.D., Ph.D., of Lund University Hospital in Sweden, and colleagues, did a cohort study of children born in Sweden and Denmark between 1994 and 2004. Using the Danish Civil Registration System, the Swedish Total Population Register and the Swedish Multigenerational Register, and the Danish and Swedish cancer registries, the researchers identified 8670 children with a paternal history of cancer, 8162 of whom were conceived naturally and 508 through ARTs.

The researchers found that a paternal history of cancer was associated with a 17% increased relative risk of major congenital malformations (however, the absolute risk was only 3.7% compared to 3.2% for offspring of males without any history of cancer), regardless of mode of conception. Indeed, the researchers found that the usage of assisted reproductive technologies for conception did not cause any statistically significant increase in the risk of malformations among offspring compared to natural conception.

The researchers write: "We observed a statistically significant but modest increase in the risk of major congenital abnormalities among offspring of males with a history of cancer, independent of the mod
'/>"/>

Contact: Kristine Crane
jncimedia@oxfordjournals.org
301-841-1285
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Enhancing arrest of cell growth to treat cancer in mice
2. Paxil Blocks Tamoxifen, Lowers Survival Odds Against Breast Cancer
3. The National Coalition for Cancer Survivorship Joins the Commission on Cancer
4. Low forms of cyclin E reduce breast cancer drugs effectiveness
5. Racial disparities persist in the diagnosis of advanced breast cancer and colon cancer in the U.S.
6. Soft drinks may increase risk of pancreatic cancer
7. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
8. Genes Play Role in Prognosis With Non-Small Cell Lung Cancers
9. Single gene mutation induces endometrial cancer
10. Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
11. Molecular pathways linked to sex, age affect outcomes in lung cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 2015 The City of West Hollywood hosted a ... commemorate the 42nd anniversary of the Supreme Court decision Roe v. ... 42 years since the Roe vs. Wade decision and the fight ... as ever,” said City of West Hollywood Councilmember Abbe Land. “We ...
(Date:1/22/2015)... 22, 2015 Gabe’s Chemo Duck Program is pleased ... first app ever created for kids with cancer. The Chemo Duck ... devices, is filled with enjoyable games to help children of all ... free app helps to keep kids entertained, educated and at ease ...
(Date:1/22/2015)... VogueQueen is a seasoned and trusted leader who consistently ... thrilled to have it lead the wedding dress industry into ... prom dresses for the global market. , “The CEO of ... he focuses on continuing the goal of operational excellence and ...
(Date:1/22/2015)... Angelweddingdress is a famous wedding dress company offering ... follow it on Facebook, Twitter, and Pinterest. The fans will ... draws a lottery every week. , Moreover, the company has ... Click Angelweddingdress homepage for more information. , ...
(Date:1/22/2015)... 2015 AngelWeddingDress, the premier women’s dress ... wedding dresses. View website of AngelWeddingDress.com to ... maternity wedding dresses online for a bridal party. AngelWeddingDress ... quality for them. Its maternity wedding dresses are specially ...
Breaking Medicine News(10 mins):Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2
... Asch, MD, MBA, the Robert D. Eilers Professor of Medicine ... Pennsylvania School of Medicine and the Wharton School, was presented ... Award by the Association American of Medical Colleges (AAMC). ... association,s annual meeting in Boston. Recognizing Dr. ...
... recovery may actually prevent happiness, researchers say , TUESDAY, Nov. ... the hope that they will get better may actually lead ... important part of happiness, but there,s a dark side of ... with their life, it can get in the way of ...
... ... ... 2009 -- Entest BioMedical, Inc. (OTCBB: ENTB) discussed its current therapies in development ... and their potential to generate significant revenue for the Company., , ,1.   Immuno-therapeutic treatment of ...
... LOS ANGELES, Nov. 10 Research conducted by the Center ... on the effects of a popular form of hyperbaric oxygen ... The "Randomized Trial of Hyperbaric Oxygen Therapy for Children with ... at 1.3 atmospheres of pressure, does not have a significant ...
... ... concern for many Americans and when the future of health is very ... the United States. Consumers now have more options to consider when making ... than now. Easy Pha-max provides superior quality plant-based nutritional products that can ...
... ... expanding its cutting edge vibration exercise technology into South America, beginning in Argentina, Chile ... and Contour Plus, are now available in South America. , ... (Vocus) November 10, 2009 -- WAVE (Whole-Body ...
Cached Medicine News:Health News:David A. Asch, M.D., M.B.A., receives AAMC Distinguished Teacher Award 2Health News:Acceptance of Chronic Illness Helps People Move On 2Health News:Entest BioMedical, Inc. Discusses How Therapies in Development May Yield Lucrative Revenue Streams for the Company 2Health News:Entest BioMedical, Inc. Discusses How Therapies in Development May Yield Lucrative Revenue Streams for the Company 3Health News:Center for Autism and Related Disorders Study Finds Hyperbaric Oxygen Therapy Ineffective Treatment for Children with Autism 2Health News:Major Biotechnology Franchise Company Expands Rapidly Throughout the USA Amidst Mounting Health Concerns 2Health News:WAVE's Revolutionary Whole-Body Advanced Vibration Exercise Is Now Available in South America 2
(Date:1/23/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/vzhr6h/video ) has ... Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - ... has been the topic of fascination since the era of ... and the Soviet Russia. Earlier even a small glimpse ...
(Date:1/23/2015)... , Jan. 23, 2015  Northwest Biotherapeutics, Inc. (NASDAQ: ... personalized immune therapies for operable and inoperable solid tumor cancers, ... at the 7 th Annual Phacilitate Immunotherapy Forum in ... presentation at Phacilitate will take place on January 26 at ...
(Date:1/23/2015)... 2015  Pete Rose, baseball,s all-time hits leader, is the new ... Myoflex, Ducere Pharma has announced. "Pete,s a Hall ... have him on board with Myoflex," said Ducere Pharma Chief ... player who is known across all generations. The passion and ...
Breaking Medicine Technology:Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3Pete Rose bets on Myoflex to relieve aches and pains 2
... VION PHARMACEUTICALS,INC. (Nasdaq: VION ) today ... trial of its lead anticancer agent Cloretazine(R),(VNP40101M) in ... acute myelogenous leukemia (AML) and high-risk,myelodysplastic syndromes (MDS). ... Ellen K. Ritchie, M.D. at The Weill-Cornell Medical ...
... May Provide New Option for Clinicians Concerned About ... Systemic Exposure When Using an ... Inc. (NYSE: ALO ),a leading global specialty pharmaceutical ... week at the American Pain Society annual,meeting demonstrate the ...
Cached Medicine Technology:Vion Pharmaceuticals Announces Initiation of Clinical Trial of Cloretazine(R) (VNP40101M) in Combination with Cytarabine 2Vion Pharmaceuticals Announces Initiation of Clinical Trial of Cloretazine(R) (VNP40101M) in Combination with Cytarabine 3Data Show FLECTOR(R) Patch Yields Significant Pain Reduction for Acute Strains, Sprains and Contusions 2Data Show FLECTOR(R) Patch Yields Significant Pain Reduction for Acute Strains, Sprains and Contusions 3Data Show FLECTOR(R) Patch Yields Significant Pain Reduction for Acute Strains, Sprains and Contusions 4Data Show FLECTOR(R) Patch Yields Significant Pain Reduction for Acute Strains, Sprains and Contusions 5Data Show FLECTOR(R) Patch Yields Significant Pain Reduction for Acute Strains, Sprains and Contusions 6Data Show FLECTOR(R) Patch Yields Significant Pain Reduction for Acute Strains, Sprains and Contusions 7
McIntyre lacrimal cannula, dual 0.3 mm side ports, straight....
West lacrimal cannula, blunt tip, 0.3 mm side opening....
Lacrimal cannula, malleable tip, straight....
The first easy-to use peroxide system offers proven efficacy that's pure and simple. The convenience of a multi-purpose cleaner/rinse in one bottle. Added power of peroxide in the other bottle....
Medicine Products: