Navigation Links
Malaria Drug Doesn't Boost Survival Odds With Prion Diseases
Date:3/11/2009

Oral quinacrine showed no benefit for brain-wasting disorders such as Creutzfeldt-Jakob

WEDNESDAY, March 11 (HealthDay News) -- The drug quinacrine doesn't prolong survival of patients with brain-wasting prion diseases such as Creutzfeldt-Jakob disease (CJD), British researchers say.

Currently, there is no way to prevent or reverse the progression of prion diseases. However, quinacrine -- an oral drug used to treat malaria and some forms of arthritis -- has been shown to be effective in treating prion-infected mouse cells.

This study included 107 patients, aged 12 and older, with prion disease. They underwent neurological assessments and clinical exams at the start of the study and again one, two, four and six months later. After that, the patients were examined every three months.

Some patients started taking 300 milligrams of quinacrine per day at the start of the study, one group started taking the drug later in the study, and others didn't take quinacrine.

During the study, 78 patients died, including 26 who took the drug immediately and 52 who initially took no quinacrine or delayed treatment.

After adjusting for factors such as disease severity and type of prion disease, the researchers found no significant difference in survival rates between those who took quinacrine and those who initially didn't take the drug.

The study was released online and was expected to be published in the April print issue of The Lancet Neurology.

More information

The U.S. National Institute of Allergy and Infectious Diseases has more about prion diseases.



-- Robert Preidt



SOURCE: The Lancet Neurology, news release, March 10, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Kenyan malaria success strengthens call for free insecticide-treated nets for all
2. MDS Pharma Services Wins Award for Management of Global Malaria Trial
3. How adhesive protein causes malaria
4. Malaria product portfolio would benefit from greater cohesion amongst stakeholders
5. USAID Announces First Malaria Communities Program Grants
6. Collaborative Drug Discovery, Inc. and St. Jude Childrens Research Hospital Make Malaria Research Data Available to Speed Drug Development
7. World Bank Group Report on Malaria in Africa Highlights Progress Towards Goal of Significantly Reducing Malaria Deaths
8. Sanofi Pasteur and Institut Pasteur Team up Against Malaria
9. Bill and Melinda Gates Call for New Global Commitment to Chart a Course for Malaria Eradication
10. Malaria No More and Sumitomo Chemical Help Protect 1.4 Million Kids from Malaria
11. Malaria Vaccine Shows Promise
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Malaria Drug Doesn't Boost Survival Odds With Prion Diseases
(Date:5/26/2016)... ... May 26, 2016 , ... MadgeTech will be showcasing its line ... in Warner, New Hampshire at the MadgeTech headquarters. With products sold in more than ... by government agencies, including NASA. , In 2012, NASA strategically set up 17 ...
(Date:5/26/2016)... ... May 26, 2016 , ... Memorial Day Weekend marks ... Amica Insurance is sharing tips to make sure your family and vehicle are ... National Safety Council, there may be 439 deaths and an additional 50,500 serious injuries ...
(Date:5/26/2016)... ... May 26, 2016 , ... Nike Yoga Camps at ... daily practices, arts & crafts, discussions, and games all geared towards enhancing your ... have combined backgrounds in kids’ yoga, collegiate sport yoga instruction, and global yoga ...
(Date:5/26/2016)... ... May 26, 2016 , ... Bunion Bootie , the manufacturer ... treatment was more than humbled by customer demand over the Mother’s Day Weekend promotion. ... sale. Now that Bunion Bootie has completely replenished its inventory levels, it hopes to ...
(Date:5/26/2016)... ... May 26, 2016 , ... Workrite ... sales leadership and to further develop their rapidly expanding portfolio of customer and ... with a concentration in Marketing and an M.B.A. with concentration in management from ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... 2016 A key trend that ... emergence of new treatments. Cardax, a development stage life ... The therapy is expected to fulfil large unmet medical ... conducting studies to develop new treatments for osteoarthritis. One ... involved in osteoarthritis are being investigated, and early trials ...
(Date:5/26/2016)... Since its commercial introduction in ... life science tool for conducting genetic studies in a ... in its new report that the industry sits on ... by a range of new applications in the clinical ... http://photos.prnewswire.com/prnh/20140723/694805 ) , Since the Human ...
(Date:5/25/2016)... HILDEN , Deutschland und GERMANTOWN, ... Zusammenarbeit mit Therawis bedient ... Entscheidungen bei Brustkrebs   QIAGEN N.V. ... QIA) gab heute bekannt, eine Lizenz- und Entwicklungsvereinbarung ... prädiktiver Assays für die Onkologie eingegangen zu sein. ...
Breaking Medicine Technology: