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Major step taken toward an open and shared digital brain atlasing framework
Date:2/8/2011

Modern brain research generates immense quantities of data across different levels of detail, from gene activity to large-scale structure, using a wide array of methods. Each method has its own type of data and is stored in different databases. Integrating findings across levels of detail and from different databases, for example to find a link between gene expression and disease, is therefore challenging and time consuming. In addition, combining data from multiple types of brain studies provides a basis for new insights and is crucial for the progress of neuroscience research. Far too often, scientific progress is hindered by technical barriers to integrating data from different experiments and laboratories.

A major step in addressing these problems, a standard toolset that allows different types of neuroscience data to be combined and compared, is now available for one of the most important subjects in experimental neuroscience: the mouse, Mus musculus. A paper describing the vision and key steps that led to the creation of a digital mouse brain atlasing framework for sharing data has just been published in the Public Library of Science (PLoS) Computational Biology journal. In this landmark publication, the INCF Digital Atlasing Task Force announces a digital atlasing framework which consists of Waxholm Space (WHS; named in honor of the group's first meeting location) and a supporting web-based Digital Atlasing Infrastructure (DAI). Together they enable the integration of data from genetic, anatomical and functional imaging studies.

"By enabling researchers to link genetic studies with large-scale brain structure and behavior, we will catalyze both basic and medical neuroscience research precisely the reason INCF was founded in the first place." Dr. Sean Hill, Executive Director, INCF.

Three major online mouse brain resources - the Allen Mouse Brain Atlas, the Edinburgh Mouse Atlas Project, and an effort from UCSD (prima
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Contact: Sean Hill
sean.hill@incf.org
46-852-487-092
INCF - International Neuroinformatics Coordinating Facility
Source:Eurekalert

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