Navigation Links
Major step taken toward an open and shared digital brain atlasing framework
Date:2/8/2011

Modern brain research generates immense quantities of data across different levels of detail, from gene activity to large-scale structure, using a wide array of methods. Each method has its own type of data and is stored in different databases. Integrating findings across levels of detail and from different databases, for example to find a link between gene expression and disease, is therefore challenging and time consuming. In addition, combining data from multiple types of brain studies provides a basis for new insights and is crucial for the progress of neuroscience research. Far too often, scientific progress is hindered by technical barriers to integrating data from different experiments and laboratories.

A major step in addressing these problems, a standard toolset that allows different types of neuroscience data to be combined and compared, is now available for one of the most important subjects in experimental neuroscience: the mouse, Mus musculus. A paper describing the vision and key steps that led to the creation of a digital mouse brain atlasing framework for sharing data has just been published in the Public Library of Science (PLoS) Computational Biology journal. In this landmark publication, the INCF Digital Atlasing Task Force announces a digital atlasing framework which consists of Waxholm Space (WHS; named in honor of the group's first meeting location) and a supporting web-based Digital Atlasing Infrastructure (DAI). Together they enable the integration of data from genetic, anatomical and functional imaging studies.

"By enabling researchers to link genetic studies with large-scale brain structure and behavior, we will catalyze both basic and medical neuroscience research precisely the reason INCF was founded in the first place." Dr. Sean Hill, Executive Director, INCF.

Three major online mouse brain resources - the Allen Mouse Brain Atlas, the Edinburgh Mouse Atlas Project, and an effort from UCSD (primarily the Cell Centered Database) - are now integrated with the INCF Digital Atlasing Infrastructure and therefore working together. This interoperability will facilitate future research as well as increase the value of previously acquired data.

WHS and DAI were developed with coordination, organization and funding from the International Neuroinformatics Coordinating Facility (INCF). They are a collaborative project, spanning more than two years, of the now retired INCF Standards in Digital Atlasing Task Force. Since then, new Task Forces have been formed to continue and expand on this work. A more detailed publication of this group's recommendations can be found in their report, published in September 2009 (see link below).


'/>"/>

Contact: Sean Hill
sean.hill@incf.org
46-852-487-092
INCF - International Neuroinformatics Coordinating Facility
Source:Eurekalert

Related medicine news :

1. One Month after Major Quake, Ongoing Crises for Haitian Children
2. Virginia House Majority Leader Morgan Griffith Sponsors Legislation Enabling Mobile Solution for Health Care SALEM, Va.
3. Major milestone achieved by our joint venture in China
4. Sunquest Announces Major Software Updates and Enhancements
5. MIT China joint venture is preparing a major commercial launch in July 2010
6. Majority of Americans Approve of President Obamas Handling of Afghanistan and National Security But Disapprove of Handling of Economic Issues, Per Franklin & Marshall College Poll With Hearst Television
7. Highlights of major physics conference in Washington, D.C.
8. The Icebox of Atlanta Selected as T-shirt Vendor for 3 Major Divisions of American Cancer Society's Relay For Life
9. Majority of Marylanders without advance medical directives
10. Pew Report Finds Majority of States Fail to Ensure Proper Dental Health & Access to Care for Children
11. Americans Remain Split on Stalled Health Care Legislation, but Some Provisions Popular Among Majorities of Democrats, Independents and Republicans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... ... strategic partnership with Connance, a healthcare industry leader providing predictive analytics to ... technology combine to provide health systems, hospitals and ambulatory surgical centers with ...
(Date:6/26/2016)... ... ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect Plugin ... whole new perspective by using the title layers in ProSlice Levels to split-up ... Levels contains over 30 Different presets to choose from. FCPX users can ...
(Date:6/25/2016)... ... 2016 , ... Austin residents seeking Mohs surgery services, can now turn to ... Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to ... fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson ... Recently, he has implemented orthobiologic procedures as a method for treating his patients. ... the first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on ... today announced that patient enrollment in its ongoing ... Duchenne) has exceeded 50% of its 24-patient target. ... in the third quarter of 2016, and to ...
(Date:6/23/2016)... June 23, 2016 , , ... July 7, 2016 , , , , LOCATION: , , ... , , , EXPERT PANELISTS:  , , , Frost & ... Analyst, Christi Bird; Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, ... The global pharmaceutical industry is witnessing an exceptional era. Several new ...
(Date:6/23/2016)... Revolutionary technology includes multi-speaker listening to conquer ... in advanced audiology and hearing aid technology, has today ... world,s first internet connected hearing aid that opens up ...      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ) , ... , TwinLink™ - the first dual communication ...
Breaking Medicine Technology: