Navigation Links
Major lung resection safer than ever, especially at the busiest hospitals
Date:4/29/2014

Toronto, ON, Canada, April 29, 2014 A major new study using data from the National Cancer Data Base details the impact of annual hospital volume on 30- and 90-day mortality rates. Investigators found that major lung surgery has become progressively safer over the last few decades, although higher death rates at low-volume hospitals and an unexpected increase in mortality at 90 days compared to 30 days were observed. The study further suggests that choosing a center that performs major lung surgery regularly can have a strong impact on survival.

Lung cancer is the leading cause of death from cancer in both men and women in the U.S. The best chance to cure lung cancer after it develops involves a combination of early detection at an "operable" stage, followed by surgery to remove the portion of the lung where the cancer developed. The number of operations for lung cancer is likely to increase with lung cancer screening.

The study used the National Cancer Data Base (NCDB) cancer treatment and outcomes database, which is a joint project co-sponsored by the American Cancer Society and the American College of Surgeons. The NCDB captures more than 80% of all new lung cancer cases treated in the U.S. each year, and evaluated data for 121,099 patients who underwent major pulmonary resection for lung cancer at more than 1,200 Commission on Cancer-accredited hospitals across the U.S. between 2007 and 2011. Survival at 30 days and 90 days after surgery and numerous risk factors for dying after the surgery were evaluated.

Analysis revealed that at all 1,200+ hospitals combined, 2.8% of patients who underwent major lung surgery (93% of which were lobectomies or bi-lobectomies) died within 30 days after their surgery during this five-year time period. This rate was lower than reported from the busiest hospitals with the highest volume of surgeries just a decade ago. Further analysis showed that annual hospital volume of major lung operations for cancer had a significant impact on both 30-day and 90-day mortality rates. The chance of death was twice as high at hospitals where less than 10 major lung cancer resections per year were performed (3.7%), compared to mortality at the busiest hospitals performing more than 90 such operations per year (1.7%). More than 10,000 of these operations took place at these lowest volume hospitals.

The researchers were surprised that the number of deaths by 90 days after surgery climbed to 5.4% overall, nearly double the rate at 30 days. "This increase in the number of deaths between 30 days and 90 days after surgery was not expected and has not been extensively reported in the past, as mortality rates after surgery are traditionally examined at 30 days. The reasons for this ongoing mortality beyond 30 days are not yet clear, but deserve further investigation," says lead author Christopher M. Pezzi, MD, Department of Surgery, Abington Health, Abington PA. The ongoing deaths between 30 and 90 days occurred at both low volume and high volume hospitals, although remained less likely at the busiest hospitals.

Other factors associated with mortality after lung surgery were anticipated, and included older age, male gender, socioeconomic factors, more advanced tumors, and a number of serious medical conditions present before the surgery. Having private insurance coverage was also associated with low (1.8%) 30-day mortality rates.

The Commission on Cancer of the American College of Surgeons has the ability to directly report to more than 1,500 accredited hospitals in the U.S. regarding their annual volume of these operations as well as the mortality rate at their hospital compared to national data. This information is part of a new national Cancer Quality Improvement Program (CQIP), which was launched in February 2014 and will be updated annually.


'/>"/>
Contact: Nicole Baritot
press@aats.org
978-299-4520
American Association for Thoracic Surgery
Source:Eurekalert

Related medicine news :

1. Genetic alterations in shared biological pathways as major risk factor for ASD
2. Gen X obesity a major problem for healthcare, workforce
3. Surgery after major stroke also improves survival odds in elderly patients
4. A majority prefers letting computers decide
5. Major third-hand smoke compound causes DNA damage -- and potentially cancer
6. Patient requests for specific drugs have major impact on prescribing, reports study in Medical Care
7. Major League Baseball players win more games following Tommy John surgery
8. NYU researchers find majority of Latinas are unaware of their risk of diabetes
9. International study shows majority of children unaware of cigarette warning labels
10. Feasible, safe to limit radiation to major salivary glands in head and neck cancer patients
11. Merrill DataSite Releases New Comments: Majority of FDI Starting to Flow Into Emerging Markets
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2017)... ... July 21, 2017 , ... The Margarian Law Firm has filed a ... its ginger ale for allegedly containing no ginger. Dr. Pepper produces the “Canada Dry” ... plaintiff Gegham Margaryan alleges Canada Dry Ginger Ale claims on its bottle that it ...
(Date:7/21/2017)... , ... July 21, 2017 , ... ... received a $5,000 grant from the C. R. Bard Foundation, Inc. ... at Somerset Hills , a service available through the nonprofit home care agency. ...
(Date:7/21/2017)... ... 21, 2017 , ... “Kids aren't born knowing how to regulate their emotions ... Tucker, Founder of St. Louis-based positive education company Generation Mindful. To help with that ... July 21st. , The kit uses colorful, engaging and educational illustrations and games ...
(Date:7/21/2017)... ... July 21, 2017 , ... West Dermatology is pleased to announce the ... July 17, 2017, Ms. Vu will join West Dermatology’s large network of medical and ... skin cancer , and more. She graduated from the University of Florida College ...
(Date:7/21/2017)... ... July 21, 2017 , ... The most ... patients improved quality of life five years after injury, according to research presented ... in Toronto, Ontario, Canada. The study followed patients for five years following surgery. ...
Breaking Medicine News(10 mins):
(Date:7/6/2017)... ThriveRx, the nutrition division of Diplomat Specialty Infusion Group, is ... nutrition support. To celebrate its anniversary, ThriveRx recently launched a ... new look with improved organization to create the best user experience for ... ... "We,ve made several great strides ...
(Date:7/5/2017)... Analytical, a company of over 2,000 employees and a leader in environmental and ... further solidifying their position as the top American owned and operated environmental testing ... ... ... Juliet, TN , enhances Pace Analytical,s capability as an innovative full service ...
(Date:6/30/2017)... 2017 In vitro diagnostics market firm Kalorama ... at least ten diagnostic companies have successfully completed financings.  ... and a loan facility.  The size of these financings ... Kalorama Information provides a monthly IVD Market Trends ... Center. "Diagnostics ...
Breaking Medicine Technology: