Navigation Links
Major advances in breast, prostate, colorectal cancer featured at ASCO Annual Meeting
Date:6/2/2014

CHICAGO Findings from four phase III clinical trials in breast, prostate, and colorectal cancers were released today at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO). The studies were presented in ASCO's Plenary session, which features the meeting's most important clinical cancer research with the greatest potential to impact patient care.

These pivotal studies reveal new ways to optimize commonly used chemotherapy, hormone therapies, and newer targeted drugs, and answer critical questions about the comparative effectiveness of two common treatment regimens for advanced colorectal cancer. All four trials were supported, at least in part, with federal funding through the U.S. National Institutes of Health.

"Today's results answer critical questions faced by people with cancer and their doctors every day. There is no doubt that patients will live longer and better because of these studies," said Clifford A. Hudis, MD, FACP, president of ASCO and chief of the Breast Cancer Medicine Service at Memorial Sloan-Kettering Cancer Center. "These major advances and many others in the history of cancer research were only possible thanks to our nation's long-standing commitment to funding clinical cancer research. That commitment must be sustained."

The Plenary studies are:

Adjuvant exemestane is more effective than tamoxifen when combined with ovarian function suppression in young women with hormone-sensitive, early-stage breast cancer: Post-surgery (adjuvant) exemestane is more effective at preventing breast cancer recurrences than tamoxifen when given with ovarian function suppression in young women with hormone receptor-positive, early breast cancer, reducing the relative risk of developing a recurrent cancer by 28 percent.

Addition of docetaxel to initial hormone therapy substantially improves survival in men with metastatic, hormone-sensitive prostate cancer: The findings suggest inclusion of docetaxel in first-line therapies for men with advanced disease who are healthy enough for chemotherapy, especially those with extensive disease spread.

First-line bevacizumab plus chemotherapy and cetuximab plus chemotherapy provide similar survival benefit for patients with metastatic colorectal cancer: Large U.S.-funded head-to-head comparison trial answers a long-standing question about the relative effectiveness of four common regimens, offering patients and providers new reassurance as they face treatment decisions.

Adding lapatinib to adjuvant trastuzumab does not improve outcomes for women with early-stage HER2-positive breast cancer: Results from the phase III ALTTO study indicate that post-surgery treatment with the two anti-HER2 drugs does not improve disease-free survival compared to standard treatment with trastuzumab alone.


'/>"/>

Contact: Wendy Stokes
wendy.stokes@asco.org
312-949-3232
American Society of Clinical Oncology
Source:Eurekalert

Related medicine news :

1. Researchers address major geographic disparities in access to kidney transplantation
2. Major discovery on the mechanism of drug resistance in leukemia and other cancers
3. Major EPSRC Programme Grant to support new Oxford Centre for Drug Delivery Devices
4. Therapy sought to reduce major risk from minor bleeding that can follow stroke
5. Major lung resection safer than ever, especially at the busiest hospitals
6. Genetic alterations in shared biological pathways as major risk factor for ASD
7. Gen X obesity a major problem for healthcare, workforce
8. Surgery after major stroke also improves survival odds in elderly patients
9. A majority prefers letting computers decide
10. Major third-hand smoke compound causes DNA damage -- and potentially cancer
11. Patient requests for specific drugs have major impact on prescribing, reports study in Medical Care
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due to a ... new, often overlooked aspect of head lice: the parasite’s ability to live away from a ... occurrence, but a necessary one in the event that lice have simply gotten out of ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van ... Wellness at Work award to iHire in recognition of their exemplary accomplishments in worksite ... 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum ...
(Date:6/24/2016)... ... ... was in a crisis. Her son James, eight, was out of control. Prone to extreme ... “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was ... other children and say he was going to kill them. If we were driving ...
(Date:6/24/2016)... Rhinebeck, NY (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of ... of companies that call for a minimum wage raise to $12 an hour by 2020 ... wage. This will restore the lost value of the minimum wage, assure the wage floor ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... actively feeding the Frederick area economy by obtaining investment capital for emerging technology ... past 2½ years that have already resulted in more than a million dollars ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ., ... developing innovative inhaled drugs, announced today that it was ... Investments reconstituted its comprehensive set of U.S. and ... "This is an important milestone for Pulmatrix," said Chief ... shareholder awareness of our progress in developing drugs for ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... - Forecast to 2022" report to their offering. ... for the patients with kidney failure, it replaces the function ... the patient,s blood and thus the treatment helps to keep ... in balance. Increasing number of ESRD patients ...
(Date:6/23/2016)... June 23, 2016 Roche (SIX: RO, ROG; ... for its Elecsys BRAHMS PCT (procalcitonin) assay as a ... septic shock. With this clearance, Roche is the first ... integrated solution for sepsis risk assessment and management. ... infection and PCT levels in blood can aid clinicians ...
Breaking Medicine Technology: