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Major advances in breast, prostate, colorectal cancer featured at ASCO Annual Meeting
Date:6/2/2014

CHICAGO Findings from four phase III clinical trials in breast, prostate, and colorectal cancers were released today at the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO). The studies were presented in ASCO's Plenary session, which features the meeting's most important clinical cancer research with the greatest potential to impact patient care.

These pivotal studies reveal new ways to optimize commonly used chemotherapy, hormone therapies, and newer targeted drugs, and answer critical questions about the comparative effectiveness of two common treatment regimens for advanced colorectal cancer. All four trials were supported, at least in part, with federal funding through the U.S. National Institutes of Health.

"Today's results answer critical questions faced by people with cancer and their doctors every day. There is no doubt that patients will live longer and better because of these studies," said Clifford A. Hudis, MD, FACP, president of ASCO and chief of the Breast Cancer Medicine Service at Memorial Sloan-Kettering Cancer Center. "These major advances and many others in the history of cancer research were only possible thanks to our nation's long-standing commitment to funding clinical cancer research. That commitment must be sustained."

The Plenary studies are:

Adjuvant exemestane is more effective than tamoxifen when combined with ovarian function suppression in young women with hormone-sensitive, early-stage breast cancer: Post-surgery (adjuvant) exemestane is more effective at preventing breast cancer recurrences than tamoxifen when given with ovarian function suppression in young women with hormone receptor-positive, early breast cancer, reducing the relative risk of developing a recurrent cancer by 28 percent.

Addition of docetaxel to initial hormone therapy substantially improves survival in men with metastatic, hormone-sensitive prostate cancer: The findings sugges
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Contact: Wendy Stokes
wendy.stokes@asco.org
312-949-3232
American Society of Clinical Oncology
Source:Eurekalert

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