Navigation Links
Major advanced cancer study to be led by Uppsala University

Several prominent cancer researchers are now joining forces in an advanced new cancer study. The goal is to understand which tumors will be difficult to treat and to find out why certain cancer drugs lose their effect after a period of use. The study is to be directed by Tobias Sjblom, associate professor of tumor biology at Uppsala University, Sweden.

The study involves a hundred cancer patients, suffering from either cancer of the large intestine or chronic lymphatic leukemia. Samples will be taken from patients both before and after drug treatment. The aim is to find out what makes so many tumors resistant to treatment a major problem in cancer care today.

"With this initiative we will have a unique opportunity to study the development of tumors up close. Several research teams will examine the samples using different analytical methods in order to get an overall picture," says Tobias Sjblom, associate professor of tumor biology at Uppsala University and director of the study.

What lies behind this resistance is not known today, but it is assumed to emerge when the tumor changes over time, mutates. This also alters the original approach to treatment. In the study scientists will be looking for mutations in all the genes in the tumors.

The study is to be performed by Uppsala scientists together with colleagues from the Royal Institute of Technology, the Swedish University of Agricultural Sciences, and Ume University. It is made possible by funding from SciLifeLab, a total of SEK 4.5 million over two years. All analyses will be done at SciLifeLab, which is a national resource center for medical and bioscience research.

"This is a model for how we want to work with large projects within SciLifeLab. Researchers receiving funding from us have access to our resources in the form of technologically advanced equipment and competence, while their own expertise in the specific research field ensures that the right questions are being asked. This enables us to generate new knowledge about diseases more quickly," says Kerstin Lindblad-Toh, director of SciLifeLab Uppsala.

This type of research is also of interest to the pharmaceuticals industry.

"The industry will have an opportunity to assess the effect of their drugs, and we hope this will provide greater insights into how we can predict how different patients will react to a certain medicine in the future," says Tobias Sjblom.


Contact: Tobias Sjblom
Uppsala University

Related medicine news :

1. Seattle Childrens lands major funding with hopes of saving thousands of infant lives
2. Group Health establishes major initiative to prevent opioid abuse and overdose
3. Nottingham scientist wins major cancer research award
4. Major award for leading expert in regenerative medicine
5. Obesity a Major Cause of Early Death in Women: Study
6. Major malaria drug research award
7. Lawmakers Urged to Consider Health Effects of Major Legislation
8. Government should consider public health implications of all major legislation
9. Deaths and major morbidity from asbestos-related diseases in Asia likely to surge in next 20 years
10. UB played major role in study on drug that reduces breast cancer in high-risk women
11. New advances in lipid genetics lead to better detection and prevention of major diseases
Post Your Comments:
(Date:11/25/2015)... ... November 25, 2015 , ... “While riding the bus, I ... Bronx, N.Y. “I thought there had to be a convenient and comfortable way to ... The PROTECTOR enables disabled individuals to safely travel during cold or inclement weather. In ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... (PHA) announces the nation’s Periwinkle Pioneers, individuals and groups responsible for advancing care ... disease. The Periwinkle Pioneers, nominated by the public, will receive special recognition throughout ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... philanthropic seniors, is resulting in a way for homeless people to have a ... have launched a new initiative whereby they are repurposing plastic bags into sleeping ...
(Date:11/25/2015)... ... November 25, 2015 , ... Since its launch in 2012, ... adult stem cell therapies to patients with chronic degenerative medical conditions. Now, the ... Registered Trademark (RTM). , Organizations are required to hold a registered trademark in ...
(Date:11/24/2015)... ... November 25, 2015 , ... Genesis Chiropractic Software ... software creates an agreement between the practice owner and the patient that automatically ... notification, and projections. Click here to learn more. , ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... FRANCISCO , Nov. 24, 2015  Thanks to ... Dignity Health St. Mary,s Medical Center,s Sister Diane Grassilli ... breast imaging capabilities in San Francisco ... an anonymous friend, stepped forward with a gift of ... for Breast Digital Mammography with Tomosynthesis and Whole Breast ...
(Date:11/24/2015)... Colo. , Nov. 24, 2015  Array ... that its Chief Executive Officer, Ron Squarer ... Healthcare Conference in New York.  The public is ... webcast on the Array BioPharma website.Event:Piper Jaffray Annual ... , Wednesday, December 2, 2015Time:1:30 p.m. Eastern Time ...
(Date:11/24/2015)... HOUSTON, TX and VANCOUVER, Nov. 24, 2015 /PRNewswire/ ... EPI; NASDAQ: EPIX ) announced today that the ... clinical study of EPI-506 as a treatment for metastatic ... States and Canada.  --> ... --> In the Phase 1/2 clinical trial, ...
Breaking Medicine Technology: