Navigation Links
Magnets Might Boost Stem Cell Therapy

In animal studies, they drew more stem cells to damaged heart tissue

TUESDAY, April 13 (HealthDay News) -- Researchers report they've used magnets to guide stem cells to damaged areas of animal hearts.

The strategy appears to make it more likely that the heart will retain the cells, potentially boosting the power of cardiac stem cell therapy.

"Stem cell therapies show great promise as a treatment for heart injuries, but 24 hours after infusion, we found that less than 10 percent of the stem cells remain in the injured area," Dr. Eduardo Marban, director of the Cedars-Sinai Heart Institute in Los Angeles, said in a news release from the institute. "Once injected into a patient's artery, many stem cells are lost due to the combination of tissue blood flow, which can wash out stem cells, and cardiac contraction, which can squeeze out stem cells. We needed to find a way to guide more of the cells directly to the area of the heart that we want to heal."

Marban and colleagues developed a technique in which they loaded cardiac stem cells with microscopic bits of iron. Then they injected the cells into rats that had heart attacks and tried to manipulate the cells with a toy magnet.

The researchers found that magnetism attracted the stem cells to injured areas, tripling the retention rate in the heart.

"Tissue viability is enhanced and heart function is greater with magnetic targeting," Marban said. "This remarkably simple method could easily be coupled with current stem cell treatments to enhance their effectiveness."

Marban and his wife, Linda, are founders of a company that has filed patents for the techniques.

The study was published online April 8 in the journal Circulation Research.

More information

The U.S. National Library of Medicine has more on heart disease.

-- Randy Dotinga

SOURCE: Cedars-Sinai Heart Institute, news release, April 8, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Molecule Discovery Might Help ALS Patients
2. New Test Might Smell Early Stage Lung Cancer
3. Video Gaming Just Might Fight Aging
4. Compounds Identified That Might Treat Nerve Diseases
5. Self-Control Just Might Be Contagious
6. Coffee, Tea Might Stave Off Diabetes
7. Breast Growth in Boys Might Be Linked to Plastics Chemical
8. In Women, Aspirin Might Ward Off Eye Trouble
9. Implanted Defibrillator Might Extend Life
10. Teen Marijuana Use Might Have Lasting Effects on Mood, Anxiety
11. Disinfectant Misuse Might Help Germs Resist Antibiotics
Post Your Comments:
(Date:11/27/2015)... VVA (PRWEB) , ... November 27, 2015 , ... ... motto of progress through sharing, the 2016 Building Better Radiology Marketing ... The conference will begin on Sunday, March 6, 2016, at Caesars Palace in ...
(Date:11/27/2015)... ... 2015 , ... The moment you stop improving is the ... the needs of advisers and clients but going above and beyond to find ... service. However, there's always room for improvement, which is why the entire Consulting ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... the largest, most successful and prominent nonprofit healthcare organizations in the country. They ... involvement with various organizations, and helped advance the healthcare industry as a whole ...
(Date:11/27/2015)... ... November 27, 2015 , ... Indosoft ... announces the incorporation of Asterisk 11 LTS (Long Term Support) into its Q-Suite ... LTS brings Q-Suite 5.10 up-to-date with a version of Asterisk that will receive ...
(Date:11/26/2015)... ON (PRWEB) , ... November 26, 2015 , ... ... of a real-time eReferral system for diagnostic imaging in the Waterloo region. Using ... BMD and Nuclear Medicine tests directly from their electronic medical record (EMR) without ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... -- Lannett Company, Inc. (NYSE: LCI ) today ... Kremers Urban Pharmaceuticals Inc. (KU), the U.S. specialty ... S.A. (Euronext: UCB). --> ... UCB for total consideration of approximately US$1.23 billion, ... capital adjustment, a deduction of certain reimbursable amounts ...
(Date:11/26/2015)... 2015 Un nuevo enfoque combina ... el cáncer avanzado.   --> Un ... de Bremachlorin para el cáncer avanzado.   ... con la terapia fotodinámica de Bremachlorin para el cáncer ... --> Clinical Cancer Research . --> ...
(Date:11/26/2015)... 2015 --> --> ... to find optimal contrast weighting of MRI for patients ... signed a research agreement with SyntheticMR in order to use ... it is possible to generate multiple contrast images from a ... has left, thus making it possible to both fine tune ...
Breaking Medicine Technology: