Navigation Links
Magnetic Fields Concentrate Drug Delivery
Date:4/24/2010

Medicine-loaded particles delivered directly to stents, researchers say

FRIDAY, April 23 (HealthDay News) -- Magnetic fields can be used to direct drug-loaded nanoparticles to metal stents in injured blood vessels, where they then release drugs that help prevent blood vessel blockages, U.S. researchers report.

In humans, stents -- small metal mesh tubes -- are often used to treat cardiovascular disease by acting as a scaffold to keep a partially clogged blood vessel open, and many are coated with medicine to further prevent the blood vessel from getting blocked.

In tests on lab rats, the new magnetic technique achieved better results at a lower dose than conventional non-magnetic therapy, according to study leader Dr. Robert J. Levy, chair of pediatric cardiology at the Children's Hospital of Philadelphia and colleagues.

Nanoparticles -- microscopic particles so tiny that a nanometer is one-millionth of a millimeter -- have recently attracted intense scientific interest. The results of this study may lead to the introduction of a new medical tool called vascular magnetic intervention.

"This can become a major platform technology for delivering drugs and other agents to specific sites where they can produce benefits in diseased or injured blood vessels," Levy said in a news release.

In this study, the researchers implanted stainless steel stents into lab rats carotid arteries -- the main arteries in the neck that supply blood to the brain. They then injected the rodents with nanoparticles impregnated with an iron oxide that responds strongly to a magnetic field. The researchers produced a uniform magnetic field around the rats for five minutes, which magnetized the stents and the nanoparticles. As a result, large numbers of the nanoparticles traveled to the stents and released a drug that helps keep arteries clear of blockages.

This use of magnetic fields to concentrate drug delivery produced better results than conventional therapy, researchers said.

The study appears in this week's online issue of the Proceedings of the National Academy of Sciences.

More information

The Society for Vascular Surgery has more about stenting.



-- Robert Preidt



SOURCE: Children's Hospital of Philadelphia, news release, April 19, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Texas Childrens Cancer Center first in Texas to magnetically lengthen 9-year-olds leg as she grows
2. Spinfinity™ Magnetic Stirring Bars From Bel-Art Products Deliver Up to Three Times Wear Resistance
3. Electromagnetic Pulses May Stem Arthritic Knee Pain
4. Electromagnetic pulses provide pain relief for osteoarthritis
5. Magnetic field measurements of the human heart at room temperature
6. VitaminSpice Elects Bill Fields to the Board of Directors
7. Tahitian Noni Pure is The Most Concentrated Bioactive Beverage Available
8. Panel questions VBAC bans, advocates expanded delivery options for women
9. Electronic Health Information Leader Says Physician Practice Redesign is Vital Next Step Towards Safer, More Effective Care Delivery
10. Targeted delivery of losartan reduces liver inflammation and scarring
11. Gourmet Diet Delivery Unites with First Lady's Battle Against Obesity The Fresh Diet Begins Delivering Meals to DC
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... ... February 24, 2017 , ... WHAT: , ... and recognition opportunities as well as advocacy for the state and region‘s technology ... February 23. The Council's Innovation Forecast event highlights innovation throughout the region ...
(Date:2/24/2017)... ... 24, 2017 , ... Dr. Ronald E. Hawkins, vice president ... of Peter A. Bell, DO, MBA, HPF, FACOEP-dist., FACEP, as the new dean ... Dr. Bell comes to Liberty from the Ohio University Heritage College of Osteopathic ...
(Date:2/24/2017)... (PRWEB) , ... February 24, 2017 , ... In the ... to be a top priority because it’s not if you will be attacked, but ... especially when it comes to digital health care. , Improvements in auditing and monitoring ...
(Date:2/24/2017)... ... ... Healthcare Associates of McKinney announced today that they have moved ... Highway 121, Suite 210, McKinney, Texas 75070. It is in the heart of ... practice has grown, the need for more space has been paramount. This beautiful ...
(Date:2/24/2017)... ... February 24, 2017 , ... With ProGlass Prism users now have the ability ... total control over position, rotation, distortion, edge softness, edge blur, chromatic aberration, individual glass ... , With ProGlass Prism users are given the tools and effects to generate ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)...  Xynomic Pharmaceuticals, Inc., an oncology drug research ... acquired exclusive worldwide rights to develop, manufacture and ... targeting hematological and solid tumors. To ... 2 clinical trials of Abexinostat in US, EU ... been completed, demonstrating that Abexinostat is clinically active ...
(Date:2/23/2017)... Feb. 23, 2017 Visiomed, the French ... since 1997, is changing the landscape of healthcare ... patients with pro-active, custom-made solutions. Recognizing the rising ... and affordable healthcare without walls, Visiomed has launched ... developed with healthcare professionals that is empowering the ...
(Date:2/23/2017)... 2017  Genesis Healthcare Services has merged with Hospice ... by Bill Monast , President and CEO of ... Nathan Feltman , executives with Home Health Depot, Inc., ... This acquisition helps Hospice Cloud maintain its ... durable medical equipment (DME) solutions for the hospice industry. ...
Breaking Medicine Technology: