Navigation Links
Magnetic Fields Concentrate Drug Delivery
Date:4/24/2010

Medicine-loaded particles delivered directly to stents, researchers say

FRIDAY, April 23 (HealthDay News) -- Magnetic fields can be used to direct drug-loaded nanoparticles to metal stents in injured blood vessels, where they then release drugs that help prevent blood vessel blockages, U.S. researchers report.

In humans, stents -- small metal mesh tubes -- are often used to treat cardiovascular disease by acting as a scaffold to keep a partially clogged blood vessel open, and many are coated with medicine to further prevent the blood vessel from getting blocked.

In tests on lab rats, the new magnetic technique achieved better results at a lower dose than conventional non-magnetic therapy, according to study leader Dr. Robert J. Levy, chair of pediatric cardiology at the Children's Hospital of Philadelphia and colleagues.

Nanoparticles -- microscopic particles so tiny that a nanometer is one-millionth of a millimeter -- have recently attracted intense scientific interest. The results of this study may lead to the introduction of a new medical tool called vascular magnetic intervention.

"This can become a major platform technology for delivering drugs and other agents to specific sites where they can produce benefits in diseased or injured blood vessels," Levy said in a news release.

In this study, the researchers implanted stainless steel stents into lab rats carotid arteries -- the main arteries in the neck that supply blood to the brain. They then injected the rodents with nanoparticles impregnated with an iron oxide that responds strongly to a magnetic field. The researchers produced a uniform magnetic field around the rats for five minutes, which magnetized the stents and the nanoparticles. As a result, large numbers of the nanoparticles traveled to the stents and released a drug that helps keep arteries clear of blockages.

This use of magnetic fields to concentrate drug delivery produced better results than conventional therapy, researchers said.

The study appears in this week's online issue of the Proceedings of the National Academy of Sciences.

More information

The Society for Vascular Surgery has more about stenting.



-- Robert Preidt



SOURCE: Children's Hospital of Philadelphia, news release, April 19, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Texas Childrens Cancer Center first in Texas to magnetically lengthen 9-year-olds leg as she grows
2. Spinfinity™ Magnetic Stirring Bars From Bel-Art Products Deliver Up to Three Times Wear Resistance
3. Electromagnetic Pulses May Stem Arthritic Knee Pain
4. Electromagnetic pulses provide pain relief for osteoarthritis
5. Magnetic field measurements of the human heart at room temperature
6. VitaminSpice Elects Bill Fields to the Board of Directors
7. Tahitian Noni Pure is The Most Concentrated Bioactive Beverage Available
8. Panel questions VBAC bans, advocates expanded delivery options for women
9. Electronic Health Information Leader Says Physician Practice Redesign is Vital Next Step Towards Safer, More Effective Care Delivery
10. Targeted delivery of losartan reduces liver inflammation and scarring
11. Gourmet Diet Delivery Unites with First Lady's Battle Against Obesity The Fresh Diet Begins Delivering Meals to DC
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A ... 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the ... history as home to some of the world’s leading providers of cereal and other ...
(Date:6/26/2016)... Michigan (PRWEB) , ... June 26, 2016 , ... ... to fertility once they have been diagnosed with endometriosis. These women need a ... they also require a comprehensive approach that can help for preservation of fertility ...
(Date:6/25/2016)... ... 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily ... of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures ... . Simply select a ProHand generator and drag it above media or text in ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health and ... their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards took ... the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to receive ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 27, 2016  VMS Rehab Systems, Inc. ... will take whatever measures required to build a strong ... which is currently listed on the OTC Markets-pink current ... Chairman and CEO, "We are seeing an anomaly in ... understand, not only by the Company, but shareholders and ...
(Date:6/24/2016)... 24, 2016  Collagen Matrix, Inc., ("Collagen Matrix") ... manufacturing of collagen and mineral based medical devices ... Bill Messer has joined the company ... leverage the growing portfolio of oral surgery, neurosurgery, ... Bill joins the Collagen Matrix executive team as ...
(Date:6/24/2016)... 24, 2016 ... the addition of the " Global Markets for ... This report focuses on ... updated review, including its applications in various applications. The ... which includes three main industries: pharmaceutical and biotechnology, food ...
Breaking Medicine Technology: