Navigation Links
MU researchers show potential for new cancer detection and therapy method
Date:4/22/2010

University of Missouri School of Medicine scientists explain a potentially new early cancer detection and treatment method using nanoparticles created at MU in an article published in the Proceedings of the National Academy of Sciences. The article illustrates how engineered gold nanoparticles tied to a cancer-specific receptor could be targeted to tumor cells to treat prostate, breast or lung cancers in humans.

"When injected into the body, the Gastrin Releasing Peptide (GRP) cancer receptor serves as a signaling device to the gold nanoparticle, which allows for targeted delivery to the tumor site," said Kattesh Katti, PhD, who wrote the article with Raghuraman Kannan, PhD. "Consequently, the radiotherapeutic properties of such nanoparticles also provides valuable imaging and therapeutic tools that can be used for early cancer detection and therapy in various human cancers."

Because GRP receptor mediated imaging and the radiotherapy specifically targets cancer cells, patients could benefit from a more effective treatment with fewer side effects. GRP receptors are abundant in prostate, breast and small lung cancer cells, and the effectiveness of Katti and Kannan's gold nanoparticles has been proved in numerous studies.

"The development of GRP-receptor specific gold nanoparticles and proof of cancer receptor specificity in living subjects, as described by Drs. Katti and Kannan, is a significant and critical step toward the utility of engineered gold nanoparticles in molecular imaging and therapy of various cancers," said Institute of Medicine member Sanjiv Sam Gambhir, MD, PhD, Virginia and D. K. Ludwig Professor, as well as director of the Molecular Imaging Program and Canary Center for Cancer Early Detection at Stanford University.

Katti, Kannan, and others with the MU School of Medicine Department of Radiology have been researching the development of tumor specific gold nanoparticles for more than five years. '/>"/>

Contact: Laura Gerding
GerdingLA@health.missouri.edu
573-882-9193
University of Missouri-Columbia
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. UCSF Researchers Identify Regulator of Human Sperm Cells
2. Researchers find broad spectrum antiviral that fights multitude of viruses
3. University of Alberta researchers develop drug interface to save lives
4. Caregivers of ICU patients are collateral damage of critical illness, say Pitt researchers
5. Researchers fight world hunger by mapping the soybean genome
6. HIV researchers solve key puzzle after 20 years of trying
7. UC Davis researchers identify brain protein for synapse development
8. UCLA cancer researchers perform complete genomic sequencing of brain cancer cell line
9. Researchers find new way to study how enzymes repair DNA damage
10. UCLA researchers image earliest signs of Alzheimers, before symptoms appear
11. Researchers find leukemia cells metabolize fat to avoid cell death
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MU researchers show potential for new cancer detection and therapy method
(Date:7/31/2014)... Setting goals for a fitness program is very important, ... weight loss. Fitness on the Go has been helping customers ... worked with 6000 customers on an individual basis throughout Canada ... monitor why customers start exercising with a personal trainer ... their program, whether or not they have a goal when ...
(Date:7/31/2014)... Coral, FL (PRWEB) July 31, 2014 ... opportunity to take charge of their financial future. ... for women, has opened registration for 6 upcoming Los ... by women, for women, and with input from Kim ... Woman and It’s Rising Time) who is passionate about ...
(Date:7/31/2014)... 2014 Today, Good Neighbor Pharmacy ... patient care by kicking off another year of ... first of many education sessions and initiatives took ... Good Neighbor Pharmacy and AmerisourceBergen’s annual conference. Sessions ... (CMS) Star Measures were a highlight and helped ...
(Date:7/31/2014)... July 31, 2014 Model moms are believers. ... Clinic reports positions in the field have grown exponentially in ... with any thriving industry, there are associated myths that need ... myths is Frontier Nursing University . Celebrating 75 years ... nurse-midwifery program in the nation. “Frontier is changing the ...
(Date:7/31/2014)... New York, NY (PRWEB) July 31, 2014 ... ( http://www.biotechniques.com ) is now available as an ... , P-LinK: A method for generating ... surface chemistry for sensors , A ... rearrangements using high-throughput next-generation sequencing , ...
Breaking Medicine News(10 mins):Health News:Fitness on the Go's Rewards Program Helps Clients Reach Their Goals 2Health News:The Independent Woman to Offer Financial Workshops in the Los Angeles Area - Developed by Women for Women 2Health News:Good Neighbor Pharmacy Reinforces Commitment to Helping Enhance Patient Care 2Health News:Good Neighbor Pharmacy Reinforces Commitment to Helping Enhance Patient Care 3Health News:Frontier Nursing University Busts Midwifery Myths In Celebration of 75th Anniversary 2Health News:Frontier Nursing University Busts Midwifery Myths In Celebration of 75th Anniversary 3Health News:Frontier Nursing University Busts Midwifery Myths In Celebration of 75th Anniversary 4Health News:Frontier Nursing University Busts Midwifery Myths In Celebration of 75th Anniversary 5Health News:BioTechniques: The International Journal of Life Science Methods Announces the Publication of the July 2014 Issue—Available in Print and Online as an Open Access Journal 2Health News:BioTechniques: The International Journal of Life Science Methods Announces the Publication of the July 2014 Issue—Available in Print and Online as an Open Access Journal 3
... its spa/gourmet green tea at the Las Vegas IECSC, ... the,International Esthetics, Cosmetics & Spa Conference (IECSC) in Las ... will feature one,product unique for its simplicity: green tea. ... Shinwa, an all-natural, organic,green Japanese karigane tea, at the ...
... - SXC Health Solutions, Corp.,("SXC" or the "Company") ... provider of,technology and pharmacy benefits management services, announces ... awarded a,three-year $35 million Pharmacy Benefits Manager (PBM) ... ("TennCare")., Under terms of the proposed agreement, ...
... 23 , - Special Library Association (SLA) ... Anniversary of SLA and Honor Two,Lifetimes of Achievement, ... John,and Jean Piety on being this year,s recipients ... of the Year Award. Mr.,and Mrs. Piety,s contributions ...
... MONDAY JUNE 23, 2008 , LOW SOCIOECONOMIC STATUS INCREASES ... with low socioeconomic status (SES) have more advanced cancers at ... of dying in the five years following cancer diagnosis, according ... the August 1, 2008 issue of CANCER , a ...
... women are struggling with the health fallout caused by a ... -- Most women don,t need a survey to tell them ... feel too sluggish to make it through the day with ... single moms, empty-nesters or grandmothers, many -- if not most ...
... (formerly,Diagnostic Ultrasound Corp.), the maker of BladderScan(R) bladder ... selection, for the second year in a row, ... in Washington State by Washington CEO Magazine., ... as the 4th "Best Company To Work For" ...
Cached Medicine News:Health News:Health and Beauty Come Full Circle: Chado-En Brings Full Benefit of Japanese Green Tea to Spas 2Health News:SXC Health Solutions announces three-year $35 million PBM contract with the State of Tennessee 2Health News:John & Jean Piety Named SLA Engineering Librarians of the Year 2Health News:Risk of death after cancer diagnosis; shift in stage of breast cancer diagnosis 2Health News:Risk of death after cancer diagnosis; shift in stage of breast cancer diagnosis 3Health News:Risk of death after cancer diagnosis; shift in stage of breast cancer diagnosis 4Health News:Risk of death after cancer diagnosis; shift in stage of breast cancer diagnosis 5Health News:So Much to Do, So Little Sleep 2Health News:So Much to Do, So Little Sleep 3Health News:Verathon Inc., Recognized, Second Year Running, as Outstanding Workplace in Washington State by Washington CEO Magazine 2
(Date:7/31/2014)... July 31, 2014 TB Alliance, a ... better, faster and affordable treatments, announced the appointment ... President, External Affairs. Mr. Brock comes to TB ... Major Donor Relations for WWF International (formerly known ... Mr. Brock will guide the TB Alliance,s resource ...
(Date:7/31/2014)... July 31, 2014  Today, Levi Ray ... extension to its PageCenterX ® content management ... designed to provide downtime reporting capabilities to healthcare ... is releasing the product for general availability, effective ... applications experience outages for a variety of reasons," ...
(Date:7/31/2014)... und KISSING, Deutschland, 31. Juli ... und Distributor eines computerunterstützten („robotischen") Koloskopie-Systems für ... (Homi) Shamir , ein weltweit anerkannter Manager ... und Kontrollgremiums zum Unternehmen stößt. ... Shamir ist ein hochangesehener globaler Visionär ...
Breaking Medicine Technology:TB Alliance Appoints Willo Brock Senior Vice President, External Affairs 2LRS Announces Downtime Reporting Solution for Healthcare 2invendo medical holt Nachum (Homi) Shamir in den Board of Directors des Unternehmens 2invendo medical holt Nachum (Homi) Shamir in den Board of Directors des Unternehmens 3
... 28 American Medical Systems® (AMS) ... devices and therapies for both male and female pelvic ... has cleared the MiniArc® Precise Single-Incision Sling System, a ... (SUI). MiniArc Precise is the next generation sling in ...
... June 28 Recondo Technology, a leading provider ... today the general availability of a suite of tools ... applications, software services, and databases. Since many Hospital Information ... have been forced to deploy new technology as "bolt-ons" ...
Cached Medicine Technology:American Medical Systems Announces FDA Clearance for MiniArc(R) Precise Single-Incision Sling 2American Medical Systems Announces FDA Clearance for MiniArc(R) Precise Single-Incision Sling 3Recondo Technology Announces Integration Initiative for US Hospital Systems 2Recondo Technology Announces Integration Initiative for US Hospital Systems 3Recondo Technology Announces Integration Initiative for US Hospital Systems 4