Navigation Links
MSU team studies connection between statins, tendon ruptures
Date:5/28/2010

EAST LANSING, Mich. Michigan State University researchers are studying the role that statins lifesavers for tens of millions of Americans trying to lower their cholesterol play in causing disabling tendon ruptures.

Francesca Dwamena, an associate professor in the College of Human Medicine's Department of Medicine, is leading the study, which will analyze more than 100,000 Blue Care Network enrollees. The study is funded by a grant from the Blue Cross Blue Shield of Michigan Foundation.

"Statins are such commonly prescribed medications, and the number of statin-users is on the rise," Dwamena said. "It is important for physicians and patients to be aware of all the risks. We need to find out definitively if statins predispose patients to this disabling complication."

While lowering cholesterol, statins also inhibit certain proteins that are required for remodeling of tendons, she said. Without remodeling, tendons become very prone to injury and potential rupture.

Dwamena and her team seek to confirm the findings from a pilot study that found increased tendon ruptures in women. Before that study, statin-induced tendon rupture was only described in case reports and post-marketing studies. With a large population-based outlook, the researchers also will assess the effects of dose, duration and type of statin on tendon rupture.

Blue Care Network enrollees between 2000 and 2009 will be included. The research team which also includes Joseph Gardiner, chairperson of MSU's Department of Epidemiology, and internal medicine residents Abhimanyu Beri and Tahmeed Contractor already has identified more than 30,000 statin users. They will be compared to more than 60,000 non-users.

Tom Fraser, a project manager at Blue Care Network, is helping with data extraction. The analysis is expected to take about one year.

This funding was obtained through the Blue Cross Blue Shield of Michigan Foundation's "Physician Investigator Initiated Research Award Program." The award provides $10,000 in seed money to investigate important issues related to the health and medical care of Michigan residents.


'/>"/>

Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Source:Eurekalert

Related medicine news :

1. New Scientific Studies Show Further Evidence of Avandia Dangers
2. University of Utah Announces New Studies on the Benefits of Treadmill Desks
3. Barrow researchers receive more than $2 million in NIH grants for nicotine studies
4. Studies Show Doctors Rapidly Forget Critical, Life-Saving Skills such as CPR and Life Support
5. PRA International Rolls out Client Access to Oracle(R) RDC for Early Phase Studies
6. Genomic Health to Present Five New Studies at 32nd Annual San Antonio Breast Cancer Symposium
7. Studies Quantify Cancer Risks From CT Scans
8. Brandeis studies evaluate visionary approach to improving eyesight
9. Ninety Percent of All Vaccine Preventable Deaths Occur in Those 65 and Older According to Highlighted Studies in the December Patient Safety Advisory
10. Acuo Technologies Announces a New Offering That Enables Sharing of Imaging Studies Securely and Affordably
11. Mimotopes Awarded a Major Peptide Library Supply Agreement by La Jolla Institute for their Studies Screening Dengue and Tuberculosis Pathogens
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/26/2017)... ... , ... ODH, Inc.™ announced today it will exhibit and speak at ... Hotel in Arlington, VA. ODH’s director of medical strategy, Candace Saldarini, M.D., will present ... population health management. , ODH will also have an exhibit booth where attendees may ...
(Date:2/25/2017)... ... 25, 2017 , ... FCPX users now have the ability to sharpen a ... ProSharpen Color users have total control over sharpening amount, sharpening radius, threshold, horizontal sharpening, ... spectrum tools users can visually see the color range effected with ease all within ...
(Date:2/24/2017)... (PRWEB) , ... February 24, 2017 , ... Only two ... International Luxury Travel Market (ILTM) show in Cannes (France), XO Private has initiated a ... tome, the 420-page book measures almost a metre across when open, weighs in at ...
(Date:2/24/2017)... (PRWEB) , ... February 24, 2017 , ... ... provost of Liberty University, has officially announced the appointment of Peter A. Bell, ... College of Osteopathic Medicine (LUCOM), beginning April 10. Dr. Bell comes to ...
(Date:2/24/2017)... ... February 24, 2017 , ... With ... is so critically important that we all are aware of our options and ... is proud to announce the launch of its newest edition of "Vision and ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... YORK , Feb. 24, 2017 ... Monteverde & Associates PC , a boutique securities firm ... New York City , announces that a class ... Massachusetts  against Inotek Pharmaceuticals Corporation ... of the Company,s securities between July 23, 2015 and December ...
(Date:2/24/2017)...  Directors from Pharma To Market Pty Ltd and Ador Consulting ... in the founding of Pharma To Market Pte Ltd, based in ... pleased to announce their expansion into Asia ... . The company are delighted to appoint Joelle Chia , ... Singapore based entity. Joelle brings with her an extensive ...
(Date:2/24/2017)...  Xynomic Pharmaceuticals, Inc., an oncology drug research ... acquired exclusive worldwide rights to develop, manufacture and ... targeting hematological and solid tumors. To ... 2 clinical trials of Abexinostat in US, EU ... been completed, demonstrating that Abexinostat is clinically active ...
Breaking Medicine Technology: