Navigation Links
MSU team studies connection between statins, tendon ruptures
Date:5/28/2010

EAST LANSING, Mich. Michigan State University researchers are studying the role that statins lifesavers for tens of millions of Americans trying to lower their cholesterol play in causing disabling tendon ruptures.

Francesca Dwamena, an associate professor in the College of Human Medicine's Department of Medicine, is leading the study, which will analyze more than 100,000 Blue Care Network enrollees. The study is funded by a grant from the Blue Cross Blue Shield of Michigan Foundation.

"Statins are such commonly prescribed medications, and the number of statin-users is on the rise," Dwamena said. "It is important for physicians and patients to be aware of all the risks. We need to find out definitively if statins predispose patients to this disabling complication."

While lowering cholesterol, statins also inhibit certain proteins that are required for remodeling of tendons, she said. Without remodeling, tendons become very prone to injury and potential rupture.

Dwamena and her team seek to confirm the findings from a pilot study that found increased tendon ruptures in women. Before that study, statin-induced tendon rupture was only described in case reports and post-marketing studies. With a large population-based outlook, the researchers also will assess the effects of dose, duration and type of statin on tendon rupture.

Blue Care Network enrollees between 2000 and 2009 will be included. The research team which also includes Joseph Gardiner, chairperson of MSU's Department of Epidemiology, and internal medicine residents Abhimanyu Beri and Tahmeed Contractor already has identified more than 30,000 statin users. They will be compared to more than 60,000 non-users.

Tom Fraser, a project manager at Blue Care Network, is helping with data extraction. The analysis is expected to take about one year.

This funding was obtained through the Blue Cross Blue Shield of Michigan Foundation's "Physicia
'/>"/>

Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New Scientific Studies Show Further Evidence of Avandia Dangers
2. University of Utah Announces New Studies on the Benefits of Treadmill Desks
3. Barrow researchers receive more than $2 million in NIH grants for nicotine studies
4. Studies Show Doctors Rapidly Forget Critical, Life-Saving Skills such as CPR and Life Support
5. PRA International Rolls out Client Access to Oracle(R) RDC for Early Phase Studies
6. Genomic Health to Present Five New Studies at 32nd Annual San Antonio Breast Cancer Symposium
7. Studies Quantify Cancer Risks From CT Scans
8. Brandeis studies evaluate visionary approach to improving eyesight
9. Ninety Percent of All Vaccine Preventable Deaths Occur in Those 65 and Older According to Highlighted Studies in the December Patient Safety Advisory
10. Acuo Technologies Announces a New Offering That Enables Sharing of Imaging Studies Securely and Affordably
11. Mimotopes Awarded a Major Peptide Library Supply Agreement by La Jolla Institute for their Studies Screening Dengue and Tuberculosis Pathogens
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... For Dr. Iris Hunter, a job is ... extension of her life’s mission. Her extensive experience in the ... of FirstLight HomeCare, make it clear that Hunter’s mission is ... my work makes a difference in the lives of others,” ... after much research, I felt ready to start on this ...
(Date:10/22/2014)... 22, 2014 The Louis ... is dedicated to distribute health information technology innovation ... worldwide announced the development of six key guiding ... when receiving healthcare. These are an expansion of ... “providing care that is respectful of and responsive ...
(Date:10/22/2014)... Cheap Hosting USA is among the most distinguished review ... that iPower ( http://www.best-cheap-hosting-usa.com/go/iPower/ ) is the best cheap ... , “iPower is one of the most reliable hosting ... of useful products for new and old clients. What’s ... and a number of features which will appeal to ...
(Date:10/22/2014)... Mission Viejo, CA (PRWEB) October 22, 2014 ... that Jay Cormier, Sr. Vice President of Sales, will ... at the upcoming Meetings Technology Expo on October 28, ... will also be hosting a booth as well as ... on how Lintelus Meeting can create a more engaging ...
(Date:10/22/2014)... HealthDay Reporter , TUESDAY, Oct. 21, 2014 ... are only about half as likely as white women to ... indicates, and the racial disparity persists even when donor eggs ... white patients became pregnant after IVF, compared to about 17 ... cycles over two years to tease out the impact of ...
Breaking Medicine News(10 mins):Health News:Dr. Iris Hunter to Host Grand Opening of FirstLight HomeCare Tomorrow 2Health News:The Sullivan Institute for Healthcare Innovation Announces Release of Guiding Principles for Patient Experience-Centered Care 2Health News:Best Cheap Hosting USA Has Recently Announced The Best Cheap Web Hosting Companies In 2014 2Health News:Jay Cormier, Sr. Vice President of Sales for Lintelus, Speaks about Event Technology Integration at Meetings Technology Expo in NYC 2Health News:Black Women Fare Worse With Fertility Treatments, Study Says 2Health News:Black Women Fare Worse With Fertility Treatments, Study Says 3
... rare liver transplant surgery has been conducted by Indian doctors ... boy. The surgery took place at the Asha Dinesh Institute ... child who was afflicted by a congenital disease. ... who was born with itching and jaundice was now near ...
... drug addicts is beginning to yield results in Scotland, with ... 2004. Heroin users accounted for 8,000 of this figure. //This ... trying to get back to normal life. ... said that the percentage of heroin users is falling. About ...
... Proteins are stable there are certain conditions under ... the unbounded proteins leading to protein aggregation called ... responsible for causing neurodegenerative disorders such as Alzheimer ... Autònoma de Barcelona, led by the researcher Salvador ...
... stem cells, which can be effectively fused with other cells ... to a study.// ,Researchers at Oregon Health and Science ... in fighting disease. , ,The researchers, headed by Markus ... 1, which causes jaundice and cirrhosis of the liver, can ...
... on Wednesday doctors and hospitals in the global healthcare destination ... ,Six hospitals in Chennai, two in Kumbakonam, 350 km from ... were raided by 300 IT officials simultaneously. About Rs.6 million ... worth several millions were seized in the raids from the ...
... found to be responsible for transferring the amino ... for reducing oxidative stress as Cysteine present in ... activity in brain.// Free radicals are responsible for ... Raymond Swanson and his team from Neurology and ...
Cached Medicine News:
(Date:10/22/2014)... Calif. , Oct. 21, 2014 Influenza will ... flu-associated deaths in the United States ... viruses are thought to spread is from person to person ... Ebola has a serve way of death, but kills much ... Ebola is also done by human fluids including sweat, saliva, ...
(Date:10/22/2014)... , Oct. 22, 2014 Sanomedics International ... 2014 report by Global Research & Data Services, demand ... year from 2014 through 2018, as demand for more ... is the world,s largest market for thermometers, ... advanced thermometers is Sanomedics International Holdings, Inc. ...
(Date:10/22/2014)... 2014 Provectus Biopharmaceuticals, Inc. (NYSEMKT: PVCT) specializes ... investigational drug for cancer, is designed for injection into ... Its oncology focus is on melanoma, breast cancer and ... trials of PV-10 as a therapy for metastatic melanoma, ... dermatitis and psoriasis. This summer, the ...
Breaking Medicine Technology:WholeHealth Products is proud to be releasing its Influenza A and B combo test, on the heels of the announcing of its phase 2 completion of the Rapid Ebola Test 2Sanomedics International Holdings Analyst Report: Taking Some Heat by BrokerBank Securities, Inc. 2Provectus Biopharmaceuticals Looks at the Asian Markets: Analyst Coverage by Small Cap Traders 2
... ultra rapid acting insulin presented at the American Diabetes ... ORLEANS, June 6 /PRNewswire-FirstCall/ -- ... investigational ultra rapid acting insulin AFRESA(R) (insulin human [rDNA ... to standard of care therapies in controlling post-meal blood ...
... June 6 Boehringer Ingelheim Pharmaceuticals, Inc. today announced ... the type 2 diabetes therapeutic area. The Company ... clinical development worldwide. New Phase II data results ... inhibitor and the Company,s lead diabetes compound, were presented ...
Cached Medicine Technology:Studies Show AFRESA(R) Controls Post-Meal Sugar Levels With Less Weight Gain and Hypoglycemia Risk for Diabetes Patients 2Studies Show AFRESA(R) Controls Post-Meal Sugar Levels With Less Weight Gain and Hypoglycemia Risk for Diabetes Patients 3Studies Show AFRESA(R) Controls Post-Meal Sugar Levels With Less Weight Gain and Hypoglycemia Risk for Diabetes Patients 4Boehringer Ingelheim Unveils Diabetes Pipeline 2Boehringer Ingelheim Unveils Diabetes Pipeline 3Boehringer Ingelheim Unveils Diabetes Pipeline 4Boehringer Ingelheim Unveils Diabetes Pipeline 5
... identified in 1980 (1) and has only recently ... (2). PYY is produced by the gut and ... is found to decrease appetite. The main form ... is PYY3-36, the N-terminal truncated form of the ...
... Human sex hormone-binding globulin (SHBG) is ... steroids with relatively high specificity and low ... bound to SHBG) and, to a much ... C18 and C19 steroid structures and regulates ...
... are polypeptide hormones which belong to ... The TGF- superfamily is a large ... control many aspects of development, reproductive ... members incude TGF-s, bone morphogenetic proteins, ...
... Activins are polypeptide hormones which ... (TGF-) superfamily. The TGF- superfamily is ... factors which control many aspects of ... (1). Other members incude TGF-s, bone ...
Medicine Products: