Navigation Links
MSU team studies connection between statins, tendon ruptures
Date:5/28/2010

EAST LANSING, Mich. Michigan State University researchers are studying the role that statins lifesavers for tens of millions of Americans trying to lower their cholesterol play in causing disabling tendon ruptures.

Francesca Dwamena, an associate professor in the College of Human Medicine's Department of Medicine, is leading the study, which will analyze more than 100,000 Blue Care Network enrollees. The study is funded by a grant from the Blue Cross Blue Shield of Michigan Foundation.

"Statins are such commonly prescribed medications, and the number of statin-users is on the rise," Dwamena said. "It is important for physicians and patients to be aware of all the risks. We need to find out definitively if statins predispose patients to this disabling complication."

While lowering cholesterol, statins also inhibit certain proteins that are required for remodeling of tendons, she said. Without remodeling, tendons become very prone to injury and potential rupture.

Dwamena and her team seek to confirm the findings from a pilot study that found increased tendon ruptures in women. Before that study, statin-induced tendon rupture was only described in case reports and post-marketing studies. With a large population-based outlook, the researchers also will assess the effects of dose, duration and type of statin on tendon rupture.

Blue Care Network enrollees between 2000 and 2009 will be included. The research team which also includes Joseph Gardiner, chairperson of MSU's Department of Epidemiology, and internal medicine residents Abhimanyu Beri and Tahmeed Contractor already has identified more than 30,000 statin users. They will be compared to more than 60,000 non-users.

Tom Fraser, a project manager at Blue Care Network, is helping with data extraction. The analysis is expected to take about one year.

This funding was obtained through the Blue Cross Blue Shield of Michigan Foundation's "Physician Investigator Initiated Research Award Program." The award provides $10,000 in seed money to investigate important issues related to the health and medical care of Michigan residents.


'/>"/>

Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Source:Eurekalert

Related medicine news :

1. New Scientific Studies Show Further Evidence of Avandia Dangers
2. University of Utah Announces New Studies on the Benefits of Treadmill Desks
3. Barrow researchers receive more than $2 million in NIH grants for nicotine studies
4. Studies Show Doctors Rapidly Forget Critical, Life-Saving Skills such as CPR and Life Support
5. PRA International Rolls out Client Access to Oracle(R) RDC for Early Phase Studies
6. Genomic Health to Present Five New Studies at 32nd Annual San Antonio Breast Cancer Symposium
7. Studies Quantify Cancer Risks From CT Scans
8. Brandeis studies evaluate visionary approach to improving eyesight
9. Ninety Percent of All Vaccine Preventable Deaths Occur in Those 65 and Older According to Highlighted Studies in the December Patient Safety Advisory
10. Acuo Technologies Announces a New Offering That Enables Sharing of Imaging Studies Securely and Affordably
11. Mimotopes Awarded a Major Peptide Library Supply Agreement by La Jolla Institute for their Studies Screening Dengue and Tuberculosis Pathogens
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... March 24, 2017 , ... Vighter established its NAEMT Authorized ... providing Prehospital Trauma Life Support (PHTLS) course scholarships to four medics assigned to ... developed in cooperation with the American College of Surgeons to promote critical thinking ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... world countries to hospitals in the United States, it’s a threat that is ... current obstacles facing infection prevention and offers strategies for the healthcare community to ...
(Date:3/24/2017)... Farifax, VA (PRWEB) , ... March 24, 2017 , ... ... its 2017 Quest Awards . The annual awards, now in their 12th year, ... marketing peers selects the winners. , In 2016, the awards were retooled to recognize ...
(Date:3/24/2017)... ... , ... Texas Physical Therapy Specialists (TexPTS) is pleased to announce the ... clinic is the group’s 7th location in San Antonio and 23rd in Texas. ... care from the clinic, which opened March 22, 2017. , The team ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... related services to families and business owners across eastern Michigan, is connecting with ... families struggling with financial difficulties. , The Oxford/Orion FISH Food Pantry works to ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... LONDON , March 23, 2017 ... comprehensive research report created through extensive primary research ... research, the report aims to present the analysis ... basis of Procedure (Replacement and Repair); Replacement Procedure ... (TAVR)), Repair By Technique (Surgical Devices, Balloon Valvuloplasty, ...
(Date:3/23/2017)... 23, 2017  The U.S. Food and Drug Administration ... treatment of adults and pediatric patients 12 years and ... who have not received prior chemotherapy. This is the ... form of skin cancer. "While skin cancer ... a rare form called Merkel cell cancer have not ...
(Date:3/23/2017)... SAN DIEGO and VANCOUVER, British ... Inc. (NASDAQ: SPHS ) (the "Company" or ... for the treatment of urological diseases, today announced that ... which evaluated the drug as a focal treatment for ... on March 26, 2017 at the 32 nd ...
Breaking Medicine Technology: