Navigation Links
MSU researchers make new discoveries on what does and doesn't affect immune system
Date:2/4/2008

EAST LANSING, Mich. -- Scientists know that a number of factors can affect the body's immune system: poor diet, certain steroids, chronic stress. Now researchers at Michigan State University have discovered that an appetite-controlling hormone also affects the immune system, while natural versions of certain steroids do not.

Both studies are reported in this week's online edition of the Proceedings of the National Academy of Sciences.

"These two studies, while not directly related, show that the neuroendocrine system plays a big role in both the immune system and obesity," said Pamela Fraker, MSU professor of biochemistry and molecular biology and lead scientist for both projects. "MSU is one of the few places studying the relationship between metabolism, the immune system and the neuroendocrine system."

A new role for leptin

One MSU research team discovered that leptin, a hormone produced by fat cells, supports white blood cell production in the body, enhancing immune function. This is the first time leptin's effect on the immune system has been demonstrated.

Scientists have long known that leptin helps control how much a person eats as well as how quickly the body burns energy.

"Many investigators have been trying to unlock the key to obesity for years," said Fraker. "The more fat a person has, the more leptin there is in the bloodstream. In obese people, it seems that the body becomes leptin-resistant -- the signals get jammed. So giving obese people leptin doesn't help them lose weight."

The MSU scientists were examining ob/ob mice (genetically programmed to have non-functional leptin) and db/db mice (genetically programmed to have non-functional leptin receptors), giving them supplemental leptin to study its effects. While causing the mice to eat less, the big surprise was leptin's effect on the immune system. The mice that were given leptin had double the number of B cells, a type of white
'/>"/>

Contact: Pam Fraker
fraker@msu.edu
517-353-3513
Michigan State University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers identify markers that may predict diabetes in still-healthy people
3. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
4. Bipolar disorder relapses halved by Melbourne researchers
5. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
6. High and mighty: first common height gene identified by researchers behind obesity gene finding
7. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
8. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
9. Researchers develop long-lasting growth hormone
10. Jefferson immunology researchers halt lethal rabies infection in brain
11. Purdue researchers develop technology to detect cancer by scanning surface veins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2015)... The grand celebration got off to a festive start with ... Deb then introduced Sandy Valentine, the wife of CCAR’s Executive ... his Walk for Recovery on the Appalachian Trail. ... gratitude to the volunteers via video. Board President Tom Kirk ... CCAR’s mission. Volunteer Manager Conrad Sienkiewicz read the names ...
(Date:4/25/2015)... (PRWEB) April 25, 2015 In observance ... will join The Million Nets Pledge, a two-year pledge ... to protect refugee families with one million bednets by ... increased work with UN partners to protect children, refugees, ... malaria. , “There has been a large surge ...
(Date:4/25/2015)... NY (PRWEB) April 25, 2015 By definition, ... and data for the enterprise relying on their judgement and ... smoothly. But according to an article published in ... many times actually be doing a disservice to their responsibilities ... are dotted and t’s are crossed when it comes to ...
(Date:4/25/2015)... York New York (PRWEB) April 25, 2015 ... that Dr. Jerry Blaivas has been chosen by the New ... for his contributions to medicine in the field of Urology. ... the best in his speciality, Genito-Urinary diseases. He was ... specifically in the field of urology. Not only did ...
(Date:4/24/2015)... (PRWEB) April 24, 2015 Constellations Recovery ... residence in Westchester County. Just 35 miles from New ... individuals back into everyday life while recovering from addiction. ... 7, 2015, will allow therapists, doctors and treatment centers ... learn more about the opportunities offered by Constellations Recovery., ...
Breaking Medicine News(10 mins):Health News:The Connecticut Community for Addiction Recovery (CCAR) honors its volunteers during National Volunteer Recognition Week. 2Health News:Supporters Worldwide Join The Million Nets Pledge on World Malaria Day 2Health News:Supporters Worldwide Join The Million Nets Pledge on World Malaria Day 3Health News:Supporters Worldwide Join The Million Nets Pledge on World Malaria Day 4Health News:An Outsider’s Perspective on Cyber Security Can Only Benefit CIOs 2Health News:An Outsider’s Perspective on Cyber Security Can Only Benefit CIOs 3Health News:An Outsider’s Perspective on Cyber Security Can Only Benefit CIOs 4Health News:An Outsider’s Perspective on Cyber Security Can Only Benefit CIOs 5Health News:The 2015 Valentine Award Comes From The Heart and Goes To Famous New York Urologist 2Health News:The 2015 Valentine Award Comes From The Heart and Goes To Famous New York Urologist 3Health News:Constellations Recovery Opens The First Luxury Sober Living Residence in Westchester New York 2Health News:Constellations Recovery Opens The First Luxury Sober Living Residence in Westchester New York 3
... number of cardiac patients by 2020 if Indians do not ... above warning has been issued by leading Cardiologists in the ... number of diabetic patients are contributing to the increasing incidence ... suffers from heart diseases. ,'Since heart disease is ...
... a penis enlargement procedure. Too much hype and hoopla ... the internet and spam mails, // has ... to the researchers, it is still under weather down ... with the outcome. ,Nim Christopher, a urologist ...
... due to the new Medicare drug plan. Each plan has its ... These plans require the patients to obtain prior authorization from the ... prior authorization for different drugs. Most states have at least 40 ... make the system complicated and delay the access of the medication. ...
... Health Organisation) today projected that by 2020 road accidents ... outranking public health issues like tuberculosis, diarrhoea and HIV/AIDS.// ... are expected to increase from 135,000 in 2000 to ... from road crashes, according to a WHO report 'World ...
... in the latest edition of the British Dental Journal says ... the knowledge of the early signs and symptoms of the ... at University College, London and Guy's, King's and St Thomas' ... heard of oral cancer or mouth cancer as compared to ...
... a wake up call to obese baby boomers, who could be ... ,Dr. Beth Abramson, foundation spokesperson and cardiologist told CTV."It was ... have soared by nearly 60 per cent and a staggering 52 ... the group between 45 and 60, are not as fit as ...
Cached Medicine News:Health News:Change In Lifestyle Recommended To Avoid Cardiac Disease 2Health News:Medicare Drug Plans Are Onerous and Restrictive 2Health News:Road accidents greater threat than AIDS, TB: WHO 2
(Date:4/24/2015)... , April 24, 2015  IGI Laboratories, Inc. (NYSE ... based specialty generic pharmaceutical company, announced the Company will ... Tuesday, April 28, 2015 to discuss the 1st quarter ... listen to the call by dialing 1-888-346-3479. International participants ... should ask to be joined into the IGI Laboratories, ...
(Date:4/24/2015)...  Span-America Medical Systems, Inc. (NASDAQ:  SPAN) announced ... second quarter results on Thursday, April 30, after the ... will conduct a conference call at 10:00 a.m. ... financial and operating results for the second quarter ended ... conference call will be available online at ...
(Date:4/24/2015)... -- Introduction of new "Elements" ... for radiosurgery/SBRT   The "Elements" strategy ... the workflow for difficult to treat indications in ... comes full circle with the introduction of automated ... enable on-the-fly generation of consistent treatment plans for ...
Breaking Medicine Technology:Brainlab Introduces New Generation of VMAT* for Brain and Spine at 3rd ESTRO in Barcelona 2
... Pharmaceuticals, Inc. (Nasdaq: DUSA) announces that its ... will be issued on Friday, November 5th at 6:30 ... 8:30 a.m. Friday, November 5th - 8:30 a.m. E.D.T.If ... callers use:502-719-4466Password - DUSAA replay of the call will ...
... BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial -- CARMIEL, Israel, Nov. 2, 2010 ... ... if (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... var shortURL = ""; BitlyCB.alertResponse = function(data) { var s = ,; var first_result; // Results are keyed ...
Cached Medicine Technology:Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 2Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 3Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 4Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 5Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 6Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 7Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 8Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 9Protalix BioTherapeutics Announces Preliminary Top-Line Positive Data from taliglucerase alfa Switchover Trial 10
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: