Navigation Links
MSU researchers discover potential genetic factor in eating disorders
Date:6/4/2010

EAST LANSING, Mich. For the first time, scientists have discovered a possible biological culprit in the development of eating disorders during puberty: a type of estrogen called estradiol.

The groundbreaking pilot study led by Michigan State University found that influence of one's genes on eating disorder symptoms was much greater in pubertal girls with higher levels of estradiol than pubertal girls with lower levels of estradiol. The study appears in the journal Psychological Medicine.

Lead investigator Kelly Klump, MSU associate professor of psychology, said previous research had established that eating disorders are influenced by both genetic and environmental factors once a girl hits puberty.

The underlying effects of the genes, however, were unknown.

"The reason we see an increase in genetic influences during puberty is that the genes for disordered eating are essentially getting switched on during that time," said Klump. "This research was trying to figure out why. What's turning on the genes during puberty? And what we found is that increases in estradiol apparently are activating genetic risk for eating disorders."

Estradiol is the predominant form of estrogen in females and is responsible for the growth of reproductive organs and also influences other organs including bones.

Klump noted that researchers don't yet know which genes are being switched on by estradiol. Further, she said a larger study is needed to confirm the results of the MSU-led research.

But knowing that estradiol likely plays a role in the development of eating disorders could ultimately open the window to new treatments, said Klump, past president of the Academy of Eating Disorders.

In addition, she said, prevention efforts could be geared toward those girls who not only are in high-risk environmental contexts (such as weight-focused sports), but also those with genetic risks such as a family history of eating disorders.

The study examined the estradiol levels of nearly 200 sets of female twins, ages 10-15, from the MSU Twin Registry, which includes more than 5,000 pairs of twins in Michigan. Klump runs the registry with S. Alexandra Burt, assistant professor of psychology.


'/>"/>

Contact: Andy Henion
henion@msu.edu
517-355-3294
Michigan State University
Source:Eurekalert  

Related medicine news :

1. UCSF Researchers Identify Regulator of Human Sperm Cells
2. Researchers find broad spectrum antiviral that fights multitude of viruses
3. University of Alberta researchers develop drug interface to save lives
4. Caregivers of ICU patients are collateral damage of critical illness, say Pitt researchers
5. Researchers fight world hunger by mapping the soybean genome
6. HIV researchers solve key puzzle after 20 years of trying
7. UC Davis researchers identify brain protein for synapse development
8. UCLA cancer researchers perform complete genomic sequencing of brain cancer cell line
9. Researchers find new way to study how enzymes repair DNA damage
10. UCLA researchers image earliest signs of Alzheimers, before symptoms appear
11. Researchers find leukemia cells metabolize fat to avoid cell death
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MSU researchers discover potential genetic factor in eating disorders
(Date:8/21/2017)... Aliso Viejo, CA (PRWEB) , ... August 21, 2017 , ... ... Pixel Film Studios. Editors can quickly and easily add washed color grades to ... an image. The LUT changes every pixel’s color to the corresponding color indicated by ...
(Date:8/21/2017)... (PRWEB) , ... August 21, 2017 , ... Five chefs ... and awareness for Alzheimer’s Family Center. , Guests will be able to vote ... Beach Plaza, Braised Lamb Shank with Fennel Dill Salad, Feta Cheese Sauce & Garlic ...
(Date:8/21/2017)... ... August 21, 2017 , ... Duncan Insurance Agency ... the people of Michigan. The new initiative fundraises for the Kalamazoo Humane Society ... forefront of animal protection and welfare by addressing the root causes of pet ...
(Date:8/21/2017)... ... August 21, 2017 , ... PIXACORE , an independent full-service agency ... Top 100 agencies of the year by MM&M. , This is the first time ... important milestone for the agency. PIXACORE’s newfound recognition reflects its steady trajectory of ...
(Date:8/21/2017)... ... August 21, 2017 , ... San Diego physician and surgeon ... reform plan, has announced his candidacy for the 52nd Congressional District currently held by ... America’s Promise. Coming to this country at age eleven after suffering homelessness and hardship ...
Breaking Medicine News(10 mins):
(Date:8/10/2017)... , Aug. 10, 2017  Physical Rehabilitation Network (PRN), ... in Lakewood, Colorado . The reputable clinic ... Lipkin , PT, DPT with his staff of four clinicians. ... of Pittsburgh and brings over 10 years of experience with ... Belmar PT marks the 10th PRN clinic in and ...
(Date:8/8/2017)... Aug. 8, 2017   ... diluted (GAAP) loss per share from continuing operations ... revenues increased 16 percent to $110 million ... 27 percent to $161 million ... from continuing operations increased 8 percent to $0.93 ...
(Date:8/7/2017)... Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), a global ... Directors has approved the payment of a quarterly cash dividend ... The cash dividend of $0.24 per ... to stockholders of record as of the close of business ... to approval of the Board of Directors and may be ...
Breaking Medicine Technology: