Navigation Links
MSU researchers discover potential genetic factor in eating disorders
Date:6/4/2010

EAST LANSING, Mich. For the first time, scientists have discovered a possible biological culprit in the development of eating disorders during puberty: a type of estrogen called estradiol.

The groundbreaking pilot study led by Michigan State University found that influence of one's genes on eating disorder symptoms was much greater in pubertal girls with higher levels of estradiol than pubertal girls with lower levels of estradiol. The study appears in the journal Psychological Medicine.

Lead investigator Kelly Klump, MSU associate professor of psychology, said previous research had established that eating disorders are influenced by both genetic and environmental factors once a girl hits puberty.

The underlying effects of the genes, however, were unknown.

"The reason we see an increase in genetic influences during puberty is that the genes for disordered eating are essentially getting switched on during that time," said Klump. "This research was trying to figure out why. What's turning on the genes during puberty? And what we found is that increases in estradiol apparently are activating genetic risk for eating disorders."

Estradiol is the predominant form of estrogen in females and is responsible for the growth of reproductive organs and also influences other organs including bones.

Klump noted that researchers don't yet know which genes are being switched on by estradiol. Further, she said a larger study is needed to confirm the results of the MSU-led research.

But knowing that estradiol likely plays a role in the development of eating disorders could ultimately open the window to new treatments, said Klump, past president of the Academy of Eating Disorders.

In addition, she said, prevention efforts could be geared toward those girls who not only are in high-risk environmental contexts (such as weight-focused sports), but also those with genetic risks such as a family history of eating disorders.

The study examined the estradiol levels of nearly 200 sets of female twins, ages 10-15, from the MSU Twin Registry, which includes more than 5,000 pairs of twins in Michigan. Klump runs the registry with S. Alexandra Burt, assistant professor of psychology.


'/>"/>

Contact: Andy Henion
henion@msu.edu
517-355-3294
Michigan State University
Source:Eurekalert  

Related medicine news :

1. UCSF Researchers Identify Regulator of Human Sperm Cells
2. Researchers find broad spectrum antiviral that fights multitude of viruses
3. University of Alberta researchers develop drug interface to save lives
4. Caregivers of ICU patients are collateral damage of critical illness, say Pitt researchers
5. Researchers fight world hunger by mapping the soybean genome
6. HIV researchers solve key puzzle after 20 years of trying
7. UC Davis researchers identify brain protein for synapse development
8. UCLA cancer researchers perform complete genomic sequencing of brain cancer cell line
9. Researchers find new way to study how enzymes repair DNA damage
10. UCLA researchers image earliest signs of Alzheimers, before symptoms appear
11. Researchers find leukemia cells metabolize fat to avoid cell death
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MSU researchers discover potential genetic factor in eating disorders
(Date:10/13/2017)... ... October 13, 2017 , ... ... Pharmacy (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, ... guideline updates for the primary prevention of cardiovascular diseases during the 15th ...
(Date:10/13/2017)... ... 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills is proud ... and unique items from across the nation, this holiday-themed event will raise funds and ... the VNA. The boutique will be open Saturday, November 4 (10:00 a.m. – ...
(Date:10/13/2017)... ... 2017 , ... Talented host, actor Rob Lowe, is introducing ... new episode of "Success Files," which is an award-winning educational program broadcasted on ... subject in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance (FHC), ... will showcase a range of technology and learning solutions at the 68th Annual ... Expo to be held October 14–18, 2017 at the Mandalay Bay Resort in ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ... introduction of an innovative new design of the shoulder pad. The shoulder pad ... comfort while controlling your pain while using cold therapy. By utilizing ice and water ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  Caris Life Sciences ... on fulfilling the promise of precision medicine, today announced ... joined Caris, Precision Oncology Alliance™ (POA) as its 17 ... centers, the St. Jude Crosson Cancer Institute will help ... the use of tumor profiling, making cancer treatment more ...
(Date:10/11/2017)...  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), today provided ... Piedras, Puerto Rico , where the ... Following a comprehensive onsite ... structural damage, temporary loss of power and minimal water ... manufacturing operations have resumed, and the company expects to ...
(Date:10/10/2017)... , Oct. 10, 2017   West Pharmaceutical Services, ... solutions for injectable drug administration, today shared the results ... Adapter for improving the intradermal administration of polio vaccines. ... Vaccination Summit in May 2017 by Dr. Ondrej ... Department, World Health Organization (WHO), and recently published in ...
Breaking Medicine Technology: