Navigation Links
MSU researcher awarded $14 million to identify breast cancer risk factors
Date:9/29/2010

EAST LANSING, Mich. A team of researchers led by a Michigan State University scientist has been awarded $14 million to identify risk factors for breast cancer in young women, focusing on growth, diet, physical activity and body size during a woman's lifetime.

The five-year study, funded by the National Institutes of Health and led by Ellen Velie of the College of Human Medicine's Department of Epidemiology, will include the largest sample in the United States of black women younger than 50 diagnosed with breast cancer.

"Risk factors for breast cancer vary by age and tumor characteristics, and there hasn't been enough research on breast cancer in young women," Velie said. "Breast cancer in these women often is more aggressive and associated with a worse prognosis."

Though white women and wealthier women (both white and black) are at a higher risk for breast cancer after age 50, black women (and it also appears poorer women) are at increased risk before age 40.

"We don't yet have a clear picture about what causes these distinct patterns," Velie said.

Black women also are at a higher risk for tumors with the worse prognosis, she added.

"This is groundbreaking research because it links the social and nutritional determinants of health during a woman's lifetime with breast cancer in understudied young women," said Marsha D. Rappley, dean of MSU's College of Human Medicine.

By looking at risk factors such as early life growth patterns, physical activity, diet, body size and related genes during a woman's lifetime, Velie and her team hope to identify why women develop tumors with specific characteristics.

"Research shows that early life events, especially during puberty, can impact later risk," she said. "We want to study how these early life factors may modify later risk of breast cancer."

That information then can be used to develop interventions to help women prevent the disease.

"Given the dramatic increase in obesity and type-2 diabetes in both adults and children, it also is imperative we understand associations between these factors and breast cancer among groups at highest risk for these conditions."

The researchers will study 2,000 women diagnosed with breast cancer between 2010 and 2014 in metropolitan Detroit and Los Angeles County. They will be identified by a National Cancer Institute cancer registry. Another 2,000 women without breast cancer will be randomly selected from these two areas.

"We have an amazing, cross-disciplinary team of committed scientists from fields including social science, epidemiology, survey design, statistical genetics, physiology and pathology," Velie said.


'/>"/>

Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Source:Eurekalert  

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Tiny fruit fly could offer big clues in fight against obesity, researcher says
6. Researchers create drug to keep tumor growth switched off
7. MSU researcher linking breast cancer patients with alternative therapies
8. UT researcher receives $2.4 million to research obesity, high-risk pregnancy
9. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
10. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
11. Clemson researchers develop hands-free texting application
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MSU researcher awarded $14 million to identify breast cancer risk factors
(Date:2/24/2017)... (PRWEB) , ... February 24, 2017 , ... The narrative ... offers Erik Schanssema ’s true account of his paramedic experiences. Schanssema describes the ... disorder and his attempts to overcome them. , Schanssema, initially unsure of the ...
(Date:2/24/2017)... ... February 24, 2017 , ... The California State ... convening academic faculty engaged in or interested in palliative care education and research. The ... be held in North County San Diego on Sept. 28 and 29, 2017, on ...
(Date:2/24/2017)... , ... February 24, 2017 , ... The International Association ... annual “Imagine Me Beyond What You See” body image mannequin art competition. Selected from ... be showcased and the winner revealed at the 31st annual iaedp Symposium, March 22 ...
(Date:2/24/2017)... ... ... The Radiology Business Management Association will select the 2017 Quest ... Better Radiology Marketing Programs conference, held this year from March 5 to 7 ... given out in five categories. They are:, ,     Patient Marketing, a ...
(Date:2/24/2017)... (PRWEB) , ... February 24, 2017 , ... ... qualifying into the Senior International Elite division on February 12th. Ms. Esparza ... divisions at the elite qualifier competition held in Las Vegas, Nevada. Frida is ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... 24, 2017 Zimmer Biomet Holdings, Inc. (NYSE ... will present at the Cowen and Company 37 th ... Copley Place on Tuesday, March 7, 2017 at 11:20 ... of the presentation can be accessed at http://wsw.com/webcast/cowen38/zbh ... the conference via Zimmer Biomet,s Investor Relations website at ...
(Date:2/24/2017)... Research and Markets has announced the addition of the "Hemophilia Drugs ... ... Price Analysis and Strategies - 2016, provides drug pricing data and benchmarks ... What are the key drugs marketed for ... Hemophilia market? What are the unit prices and annual ...
(Date:2/24/2017)... HARRISBURG, Pa. , Feb. 24, 2017 ... Secretary of Drug and Alcohol Programs Jennifer Smith ... role in providing training for and using naloxone, a ... Mark McCullough , a recovery specialist and overdose ... naloxone by EMS providers. "A significant part ...
Breaking Medicine Technology: