Navigation Links
MSU investigates drug to halt Parkinson's progression
Date:7/29/2011

GRAND RAPIDS, Mich. Researchers from Michigan State University's College of Human Medicine, Van Andel Research Institute and the Translational Genomics Research Institute are investigating a drug that has the potential to not only alleviate Parkinson's symptoms but also halt the disease's progression.

A $400,000 grant from the Michael J. Fox Foundation for Parkinson's Research part of $2.4 million in funding the foundation awarded this week to institutions nationwide will fund the research project.

Researchers are focusing on the drug Fasudil, which is currently approved in Japan to improve blood flow to the brain in stroke victims and has shown similar positive outcomes in U.S. clinical trials.

In 2009, investigators from the Translational Genomics Research Institute in Arizona and Arizona State University reported that a form of Fasudil had the potential to help improve learning and memory and reduce the risk of Alzheimer's disease. Van Andel researchers also recently discovered the potential of the drug in Parkinson's when they were testing various drugs that reduce the toxicity caused by a defective PARK1 gene, a gene implicated in Parkinson's disease.

"The potential of this drug is exciting not only because it could halt disease progression where other treatments only provide symptomatic relief but also because of how quickly it could be made available to patients," said Jeffrey P. MacKeigan, head of Van Andel's Laboratory of Systems Biology and co-investigator on the project with Caryl E. Sortwell of MSU's College of Human Medicine.

"Fasudil has a very favorable safety profile in humans and already is available in Japan as an oral tablet, so we could be seeing clinical trials within two to three years," MacKeigan added.

The development of new drugs is expensive and time-consuming, said Kuldip Dave, associate director of research programs at MJFF.

"In fall 2010, MJFF launched our i
'/>"/>

Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Long Island Press Investigates Big Tobacco's Lobby to Kill Indian Cigarette Trade
2. Food Safety Law Firm Investigates Major Outbreak of E. coli Linked To Lettuce
3. Thesis investigates characteristics of society using sports activities as research tool
4. UI study investigates variability in mens recall of sexual cues
5. BUSM investigates cellular mechanisms leading to immune response in airway epithelium
6. New genomics research investigates metastatic childhood cancers
7. Herpes Drug Might Also Slow HIV Progression
8. Targeting the blood-brain barrier may delay progression of Alzheimers disease
9. Statins may slow progression of multiple sclerosis, new study finds
10. Statins May Slow Progression of Multiple Sclerosis, New Study Finds
11. Exercise may slow progression of ALS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... York, New York (PRWEB) January 22, 2015 ... filed after Fresenius Medical Care recalled its GranuFlo and ... federal multidistrict litigation underway in U.S. District Court, District ... Order dated January 20th, the Court has remanded a ...
(Date:1/22/2015)... Plainsboro, NJ (PRWEB) January 22, 2015 ... advocate and keynote speaker at the upcoming 32nd ... by ACCME-accredited Physicians’ Education Resource®, LLC (PER®) , ... breast would have gone undetected if she had not ...
(Date:1/22/2015)... IsoComforter, Inc. has introduced the most innovative ... design to treat specific body parts and muscle groups. , ... easy to use patented cold therapy machine with the innovative ... and muscle injuries. IsoComforter has become the industry leader ...
(Date:1/22/2015)... New York, NY (PRWEB) January 22, 2015 ... component of overall health care gains momentum worldwide, Rev. ... York-based HealthCare Chaplaincy Network (HCCN), will be the ... advance spiritual care in Israel’s public health system. , The ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Step into ... at the Science Museum of Virginia. Wicked Plants, the ... Wicked Plants unearths 75 poisonous, carnivorous and diabolical plants ... each room to uncover the biochemical, physical and neurological ...
Breaking Medicine News(10 mins):Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:Wicked Plants are taking over the Science Museum of Virginia 2
... By Steven Reinberg HealthDay Reporter , THURSDAY, ... rheumatoid arthritis patients live a sedentary life, a new study ... rest was the best treatment, but now experts believe physical ... strength and reduce pain, the researchers noted. "Our results ...
... emergency department for patients experiencing dizziness may not be ... Ford Hospital researchers as hospitals across the country look ... According to the Henry Ford study, less than ... emergency department revealed a more serious underlying cause for ...
... a possible cause for the loss of a tumour suppressor ... of more aggressive forms of prostate cancer. , "This ... cancer develops because we now have some insight into the ... Squire, a professor in the Department of Pathology and Molecular ...
... and neck cancers respond well to the anti-cancer drug erlotinib ... is given to patients who smoke, according to a study ... by AHNS, ASCO, ASTRO and SNM., Erlotinib is an oral ... by inhibiting specific growth receptors on the surface of the ...
... WEDNESDAY, Jan. 25 (HealthDay News) -- People who reach midlife ... for cardiovascular disease are much less likely to have a ... healthy peers, a new study suggests. "If you make ... like the fountain of youth for your heart," said lead ...
... WEDNESDAY, Jan. 25 (HealthDay News) -- A new preliminary report ... the size of large growths that can disfigure the bodies ... use for the medicine, which was first developed as a ... have erections. This time, researchers stumbled upon an alternate use ...
Cached Medicine News:Health News:Too Many Rheumatoid Arthritis Patients Inactive, Study Finds 2Health News:Too Many Rheumatoid Arthritis Patients Inactive, Study Finds 3Health News:CT scans for dizziness in the ER: Worth the cost? 2Health News:Erlotinib dose-adjusted for smoking status effective as first treatment for head and neck cancer 2Health News:Optimal Heart Health Starts Early: Study 2Health News:Optimal Heart Health Starts Early: Study 3Health News:Active Ingredient in Viagra Shrunk Disfiguring Growths in Kids 2Health News:Active Ingredient in Viagra Shrunk Disfiguring Growths in Kids 3
(Date:1/23/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/5dh22x/urinary_catheters ) ... Market (Indwelling or Foley Catheters, Intermittent Catheters and Male ... Share, Growth, Trends and Forecast 2014 - 2020" ... present, the global market for urinary catheters is experiencing ...
(Date:1/23/2015)... a third of reproductive-aged women enrolled in Medicaid, and more ... prescription for an opioid pain medication each year during 2008-2012, ... Weekly Report (MMWR). Opioids are typically prescribed ... They are also found in some prescription cough medications. The ...
(Date:1/23/2015)... , Jan. 23, 2015  Now available for sale, ... 7,849,611) support that prevents ankle sprains by cushioning the ... it fits securely around the outside of any shoe ... & comfort while still offering protection against sprains. With ...
Breaking Medicine Technology:Urinary Catheters Market (Indwelling or Foley Catheters, Intermittent Catheters and Male External or Condom Catheters) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Urinary Catheters Market (Indwelling or Foley Catheters, Intermittent Catheters and Male External or Condom Catheters) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2
... , FREMONT, Calif., Nov. 19 WaferGen Biosystems, ... of state-of-the-art genetic analysis systems, today announced a ... of genes using the SmartChip(TM) Real-Time PCR System. ... PCR system, WaferGen will offer universities, pharmaceutical and ...
... SAN DIEGO, Nov. 19 Accumetrics, Inc., developer of ... platelet reactivity, announces that its market-leading VerifyNow P2Y12 Test ... study, which was presented during a Late Breaking Clinical ... Sessions. The VerifyNow P2Y12 Test is used to measure ...
Cached Medicine Technology:WaferGen to Introduce New Service for Gene-Expression Profiling Using the SmartChip(TM) Real-Time PCR System 2WaferGen to Introduce New Service for Gene-Expression Profiling Using the SmartChip(TM) Real-Time PCR System 3WaferGen to Introduce New Service for Gene-Expression Profiling Using the SmartChip(TM) Real-Time PCR System 4VerifyNow(R) System Highlighted in POPular Study Comparing Platelet Reactivity Tests 2
Series I Small Joint Arthroscopy Hand Instruments feature small yet durable instruments specifically designed for small joint arthroscopy. They are available in a variety of low profile styles: strai...
Series I Small Joint Arthroscopy Hand Instruments feature small yet durable instruments specifically designed for small joint arthroscopy. They are available in a variety of low profile styles: strai...
Series I Small Joint Arthroscopy Hand Instruments feature small yet durable instruments specifically designed for small joint arthroscopy. They are available in a variety of low profile styles: strai...
Low-profile, hand-held instrument....
Medicine Products: