Navigation Links
MS that runs in families appears more severe than non-familial MS
Date:10/12/2007

ads to mild to serious disability, from slight numbness of the limbs to loss of vision and paralysis.

The cohort of 759 patients involved in the study ranged in age from 36-56, with an average disability score of 3.4 on a scale of 0-10. A higher number indicates more disability.

Of these patients, 478 had relapsing-remitting MS, involving acute attacks with full or partial recovery; 222 had secondary-progressive MS, characterized by occasional attacks and sustained progression; 30 had primary-progressive MS with steady worsening from onset, and 29 had experienced their first attack.

Twenty-six percent, or 198, had a positive family history of MS. The breakdown between first-, second- or third-degree relatives with MS was 81/35/82. All patients obtained full clinical and quantitative MRI evaluations.

Using MRI, researchers measured the number and volume of lesions (plaques), which represent areas of demeylination; atrophy of the whole brain, white matter (the neural pathways), grey matter (brain regions) and the cortex, as well as employing additional imaging techniques.

There were no significant differences between familial and sporadic cases based on age, disease duration, disease course, disability score and total lifetime use of disease-modifying drugs.

Analysis showed that compared to patients with no family history of MS, familial MS patients had significantly more destructed lesions, and significantly lower volume of whole brain, white matter and gray matter, as well as other indications of greater brain degradation.

Patients whose parents, children or siblings [first-degree relatives] had MS showed more damage than patients who had cousins with MS, Zivadinov said. This indicates that the closer the relationship, the greater the risk of MS.

Of particular interest is the finding of more severe gray matter damage and more lesions, particularly in those with MS in first-degree relatives. These findings are very in
'/>"/>

Contact: Lois Baker
ljbaker@buffalo.edu
716-645-5000 x1417
University at Buffalo
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Dysfunctional Families Affect The Mental Health Of The Child
2. Alzheimers with psychosis runs in families
3. Early rising from sleep can run in families
4. Alcohol based sanitizer found to reduce illness in families
5. Kidney failure shows a tendency to run in families
6. Tendency To Smoke and Get Addicted Could Run In Families!
7. Snappy Mobiles Known To Cause Snappish Behavior in Families
8. SIDS On The Rise Among Poor Families
9. BPL Families To Receive Health Insurance: Andhra CM
10. Health Insurance Numbers Declining In American Families
11. Government’s Welfare Plan For Deprived Families Affect Other
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2015)... ... August 30, 2015 , ... On September 30, 2015, the ... of the 10 regionally accredited Maricopa Community Colleges , will be hosting a ... students pursuing employment information and opportunities. , The Expo has expanded to much more ...
(Date:8/29/2015)... ... 29, 2015 , ... "I have been a licensed physical ... specialize in manual therapy, and my invention will provide headache sufferers a solution ... muscle dysfunction throughout the body." , They developed THE RELIEVER to alleviates headaches, ...
(Date:8/29/2015)... (PRWEB) , ... August 29, 2015 , ... Dr. Tim ... mission. His mission is to increase acceptance of the chiropractic field in the ... that further debilitate them. Although Chiropractic was made available to the VA program ...
(Date:8/29/2015)... ... , ... ProDrop Particles includes over 40 particle backdrops designed for use in ... that users can shrink and stretch in the Final Cut Pro X timeline. Choose ... brightness, scale, speed, range, and flare attributes with intuitive controls found in the top-right ...
(Date:8/29/2015)... ... August 29, 2015 , ... The popular television program VOICES IN AMERICA, ... that it will be devoting an entire short segment to the subject of diabetes. ... the globe on a daily basis, but recent advancements in medical science may prove ...
Breaking Medicine News(10 mins):Health News:Estrella Mountain Community College Expo Offers ‘One-Stop’ for Employers and Students Seeking Internships, Jobs, Careers and Service Learning Opportunities 2Health News:Inventors and InventHelp Clients Develops Tension Reliever (LGI-1951) 2Health News:The Patriot Project brings Chiropractic Care to the Armed Forces and their Families - Rapid Release Technology Joins the Effort to Recruit more Doctors to Pledge 2Health News:FCPX Effects Developer, Pixel Film Studios, Releases ProDrop Particles. 2
... - Florida Upholds Contract Award To Orchid Cellmark For Multi-Year ... Paternity Testing - ... Work Underway In U.K. -, PRINCETON, N.J., July 31 Orchid Cellmark Inc.,(Nasdaq: ... financial results for the second quarter of,2008., Total revenues were $15.2 million for ...
... Offers Cost-Effective, Turnkey Digital Marketing for ... Targeted Lead Generation, ... now can market themselves directly to,America,s 31 million back pain sufferers ... LLC. The portal, http://www.backcarenetwork.com, harnesses the power of the internet ...
... Medical, Inc., a,privately held medical device company, announced today ... BMO Capital Markets 2008 Focus on,Healthcare conference on Tuesday, ... Hotel in New York City. Mr. Lien,s presentation will,include ... Details of the presentation follow: Date: ...
... launched a redesigned website that allows physicians and dentists to ... insurance plans. , ... San Clemente, ... http://www.doctordisability.com/ [disability insurance __title__ disability insurance] and life insurance ...
... hospital client King,s Daughters Medical Center (KDMC) in Brookhaven, ... as a part of the 2009 Health and Human ... the Senate Appropriations Committee earlier this month. KDMC,s grant ... (Miss.), was initiated by QHR and its strategic service ...
... is hosting a blood drive at its Phillipsburg location on Saturday, ... ... NJ (PRWEB) July 31, 2008 -- Phillipsburg Easton Honda is hosting ... from 11:00AM to 1:45PM., , , , ,"Demand for blood donations ...
Cached Medicine News:Health News:Orchid Cellmark Reports Second Quarter 2008 Financial Results 2Health News:Orchid Cellmark Reports Second Quarter 2008 Financial Results 3Health News:Orchid Cellmark Reports Second Quarter 2008 Financial Results 4Health News:Orchid Cellmark Reports Second Quarter 2008 Financial Results 5Health News:Orchid Cellmark Reports Second Quarter 2008 Financial Results 6Health News:Orchid Cellmark Reports Second Quarter 2008 Financial Results 7Health News:Orchid Cellmark Reports Second Quarter 2008 Financial Results 8Health News:Orchid Cellmark Reports Second Quarter 2008 Financial Results 9Health News:New Website Portal Delivers Pre-Qualified Spinal Decompression Patients to Participating Doctors 2Health News:New Website Portal Delivers Pre-Qualified Spinal Decompression Patients to Participating Doctors 3Health News:Cardiva Medical Announces Presentation at BMO Capital Markets 2008 Focus on Healthcare Conference 2Health News:New Website Helps Doctors and Dentists Locate Disability Insurance 2Health News:New Website Helps Doctors and Dentists Locate Disability Insurance 3Health News:Healthcare Consulting Leader QHR, Strategic Health Care, Sen. Roger Wicker Partnership Yields $500,000 Grant for King's Daughters Medical Center 2Health News:Healthcare Consulting Leader QHR, Strategic Health Care, Sen. Roger Wicker Partnership Yields $500,000 Grant for King's Daughters Medical Center 3Health News:Phillipsburg Easton Honda to Host Miller-Keystone Blood Drive 2Health News:Phillipsburg Easton Honda to Host Miller-Keystone Blood Drive 3
(Date:8/28/2015)... Research and Markets ( http://www.researchandmarkets.com/research/jq34zf/investigation ) ... on China,s Tobramycin Market, 2010-2019" report to their ... eye drop and ointment are the most common prescription ... caused by eye infection. Currently, dozens of enterprises in ... tobramycin, among which the Top 5 are s.a. Alcon- ...
(Date:8/28/2015)... Research and Markets ... the "Investigation Report on China,s Quetiapine Market, ... Developed by AstraZeneca plc, quetiapine (under the trade ... the treatment of schizophrenia. Approved by CFDA to ... the Catalogue of Drugs for the Basic National ...
(Date:8/28/2015)... Research and Markets ( http://www.researchandmarkets.com/research/sqh7xc/investigation ) ... on China,s Ranibizumab Market, 2012-2019" report to their ... by CFDA to treat wet age- related macular degeneration ... Novartis, is available in the Chinese market. However, in ... the treatment of wet AMD in China ...
Breaking Medicine Technology:Investigation Report on China's Tobramycin Market, 2015-2019 2China Quetiapine Market Investigation Report 2010-2019 2Investigation Report on China's Ranibizumab Market, 2012-2019 2
... Cytogen,Corporation (NASDAQ: CYTO) reported updated data from ... (samarium Sm-153,lexidronam injection) in combination with bortezomib ... myeloma. Data from 33 patients were presented ... of Bortezomib (Vel) and Samarium,(Sam) in Multiple ...
... 100 percent response rate achieved with VELCADE, ... /PRNewswire-FirstCall/ -- Millennium,Pharmaceuticals, Inc. (Nasdaq: MLNM) today ... clinical trials of VELCADE based,therapies that showed ... response(1) (CR) rates in newly diagnosed,multiple myeloma ...
Cached Medicine Technology:Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity,and Safety Profile of Quadramet at International Myeloma Workshop 2Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity,and Safety Profile of Quadramet at International Myeloma Workshop 3Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity,and Safety Profile of Quadramet at International Myeloma Workshop 4Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity,and Safety Profile of Quadramet at International Myeloma Workshop 5Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity,and Safety Profile of Quadramet at International Myeloma Workshop 6Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity,and Safety Profile of Quadramet at International Myeloma Workshop 7Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity,and Safety Profile of Quadramet at International Myeloma Workshop 8Velcade (bortezomib) for Injection Based Therapies Achieved,Survival Rates as High as 100 Percent in Newly Diagnosed Multiple,Myeloma Patients 2Velcade (bortezomib) for Injection Based Therapies Achieved,Survival Rates as High as 100 Percent in Newly Diagnosed Multiple,Myeloma Patients 3Velcade (bortezomib) for Injection Based Therapies Achieved,Survival Rates as High as 100 Percent in Newly Diagnosed Multiple,Myeloma Patients 4Velcade (bortezomib) for Injection Based Therapies Achieved,Survival Rates as High as 100 Percent in Newly Diagnosed Multiple,Myeloma Patients 5Velcade (bortezomib) for Injection Based Therapies Achieved,Survival Rates as High as 100 Percent in Newly Diagnosed Multiple,Myeloma Patients 6Velcade (bortezomib) for Injection Based Therapies Achieved,Survival Rates as High as 100 Percent in Newly Diagnosed Multiple,Myeloma Patients 7Velcade (bortezomib) for Injection Based Therapies Achieved,Survival Rates as High as 100 Percent in Newly Diagnosed Multiple,Myeloma Patients 8
An indirect immunofluorescence (IFA) antibody test for the detection and semiquantitation of anti-glomerular basement membrane (GBM) antibodies in human serum. Slide Detail: 6-well Monkey Kidney Subs...
An enzyme linked immunosorbant assay (ELISA) for the detection and quantitation of Rheumatoid Factor (RF) IgA isotype in human serum....
An enzyme linked immunoassay (ELISA) for the detection and semiquantitation of IgG, IgA or IgM anticardiolipin antibodies, as an aid in assessing the risk of thrombosis in individuals with Systemic L...
The ImagingPlanet 70 mm surgical microscope video adapter: Superior optical quality and precise engineering make this 70 mm focal length adapter an excellent decision for use with your Leica surgica...
Medicine Products: