Navigation Links
MS researchers find brain & cognitive reserve protect long-term against cognitive decline

West Orange, NJ. April 30, 2014. Multiple sclerosis researchers have found that brain reserve and cognitive reserve confer a long-term protective effect against cognitive decline: Sumowski JF, Rocca MA, Leavitt VM, Dackovic J, Mesaros S, Drulovic J, Deluca J, Filippi M. Brain reserve and cognitive reserve protect against cognitive decline over 4.5 years in MS. Neurology. 2014 Apr 18. doi: 10.1212/WNL.0000000000000433 [Epub ahead of print]. James Sumowski, PhD, lead author of the article, and John DeLuca, PhD, are at Kessler Foundation. Co-authors are from the Manhattan Memory Center, New York, NY, the San Raffaele Scientific Institute, Milan, Italy, and the University of Belgrade, Serbia. Neurology is the official journal of the American Academy of Neurology. Dr. Sumowski presented this research at the 2014 AAN conference in Philadelphia.

"Our research aims to answer these questions," explained Dr. DeLuca. "Why do some people with MS experience disabling symptoms of cognitive decline, while others maintain their cognitive abilities despite neuroimaging evidence of significant disease progression? Can the theories of brain reserve and cognitive reserve explain this dichotomy? Can we identify predictors of cognitive decline?"

In this study, memory, cognitive efficiency, vocabulary (a measure of intellectual enrichment/cognitive reserve), brain volume (a measure of brain reserve), and disease progression on MRI, were evaluated in 40 patients with MS at baseline and at 4.5-year followup. After controlling for disease progression, scientists looked at the impact of brain volume and intellectual enrichment on cognitive decline.

Results supported the protective effects of brain reserve and cognitive reserve," noted Dr. Sumowski. "Patients with greater intellectual enrichment experienced lesser degrees of cognitive decline. Those with greater brain reserve showed a protective effect for cognitive efficiency. This study not only confirms these protective effects of brain and cognitive reserve, it shows that these beneficial effects persist for years."


Contact: Carolann Murphy
Kessler Foundation

Related medicine news :

1. UNC researchers discover master regulator role for little-known protein in cancer cells
2. CWRU researchers profile womens employment, caregiving workloads, effort and health
3. Drug monitoring information improves regimen adherence, Carnegie Mellon researchers say
4. Researchers identify mechanism of cancer caused by loss of BRCA1 and BRCA2 gene function
5. Indiana University researchers gauge the toll of trampoline fractures on children
6. AGA showcases its commitment to improving the pipeline of minority researchers
7. Researchers identify potential new strategy to treat ovarian cancer
8. NYU Steinhardt researchers to study why male millennials risk HIV transmission
9. Researchers generate immunity against tumor vessel protein
10. Researchers at LSTM part of the international team to sequence the tsetse genome
11. Oxygen diminishes the hearts ability to regenerate, researchers discover
Post Your Comments:
Related Image:
MS researchers find brain & cognitive reserve protect long-term against cognitive decline
(Date:11/24/2015)... ... November 24, 2015 , ... With Thanksgiving right around the ... safety tips to help protect your family and vehicle. , According to the National ... Thanksgiving holiday weekend. Amica is sharing the following safety tips from the NHTSA: ...
(Date:11/24/2015)... ... ... Cold Shoulder , LLC launched their Pro Vest, the latest version of their widely ... $20,000 in under 10 hours. , The campaign, which will continue to ... to the market. , The PRO Vest provides consumers with a less expensive, one-size fits ...
(Date:11/24/2015)... PALMYRA, Wis (PRWEB) , ... November 24, 2015 ... ... Process scholarship award at Cleveland University-Kansas City (CU-KC), in Overland Park, ... scholarship from Chiropractor and University President Carl S. Cleveland III on October 16. ...
(Date:11/24/2015)... Baltimore, M.D. (PRWEB) , ... November 24, 2015 ... ... a new award for its exceptional customer service: the TrustDale certification. The award ... experience. The Baltimore stone honing , tile and grout, and hard surface ...
(Date:11/24/2015)... Boston, MA (PRWEB) , ... November 24, 2015 , ... ... What Henry Ford and Detroit Taught Me about Reinvention and Diversity by Nancy ... , Watching people suffer, with hospitals failing to adequately address the needs of patients ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... 2015   HeartWare International, Inc . (NASDAQ: ... support technologies that are revolutionizing the treatment of advanced ... Officer Doug Godshall is scheduled to present ... Conference on December 1, 2015 at 3:00 p.m. ET.  ... New York . ...
(Date:11/24/2015)... Diplomat Pharmacy, Inc. (NYSE: DPLO) announced today that ... Education and Human Resources will be presenting in the upcoming ... Plan Strategies for a Dynamic Market" on Dec. 1, 2015. ... consultant with the Cambridge Advisory Group, where she leads their ... The webinar will discuss the rapid growth of oral oncolytics, ...
(Date:11/24/2015)... 24, 2015 Teledyne DALSA , a Teledyne ... technology, will introduce its CMOS X-Ray detector for mammography ... 29 to December 3, at McCormick Place in ... diagnostic and interventional imaging will be on display in the ... of advanced CMOS X-Ray detectors is the industry benchmark for ...
Breaking Medicine Technology: