CHICAGO (July 26, 2012) -- Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) doubled at academic medical centers in the U.S. between 2003 and 2008, according to a report published in the August issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.
Researchers from the University of Chicago Medicine and the University HealthSystem Consortium (UHC) estimate hospitalizations increased from about 21 out of every 1,000 patients hospitalized in 2003 to about 42 out of every 1,000 in 2008, or almost 1 in 20 inpatients. "The rapid increase means that the number of people hospitalized with recorded MRSA infections exceeded the number hospitalized with AIDS and influenza combined in each of the last three years of the survey: 2006, 2007, and 2008," said Michael David, MD, PhD, an assistant professor of medicine at the University of Chicago and one of the study's authors.
The findings run counter to a recent CDC study that found MRSA cases in hospitals were declining. The CDC study looked only at cases of invasive MRSAinfections found in the blood, spinal fluid, or deep tissue. It excluded infections of the skin, which the UHC study includes.
MRSA infections, which cannot be treated with antibiotics related to penicillin, have become common since the late 1990s. These infections can affect any part of the body, including the skin, blood stream, joints, bones, and lungs.
The researchers attribute much of the overall increase they detected to community-associated infectionsthose that were contracted outside the healthcare setting. When MRSA first emerged it was primarily contracted in hospitals or nursing homes. "Community-associated MRSA infections, first described in 1998, have increased in prevalence greatly in the U.S. in the last decade," David said. "Meanwhile, healthcare-associated strains have generally been declining."
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