Navigation Links
MRSA Strain With Outbreak Potential Among Reports at Disease Conference

By Amanda Gardner
HealthDay Reporter

FRIDAY, Oct. 22 (HealthDay News) -- An increasingly stubborn strain of methicillin-resistant Staphylococcus aureus, or MRSA, a common bacterial infection acquired in hospitals, has been identified in Ohio, according to research presented at the annual meeting of the Infectious Diseases Society of America.

The strain, ST239 MRSA, killed 22 percent of the people it infected within 30 days, the study found. It's the first time that the strain, originally identified in Brazil, has been seen in the United States since the 1990s.

"It does have epidemic potential for outbreak," the study's co-author, Dr. Shu-Hua Wang, said. "It has increased capacity to cause invasive, serious infection."

Wang's group reported that 6.8 percent -- or 77 -- of 1,126 MRSA samples collected through the Ohio State University Health Network and seven rural hospitals in a three-year period from January 2007 to January 2010 were ST239.

Wang, who is an assistant professor of medicine at Ohio State, called for more genotyping of MRSA isolates.

A second study presented at the conference found that antibiotic prescriptions in the United States were much higher in the South than in the West, a finding that held for all types of antibiotics.

The average nationwide was 0.85 prescriptions per person in 2009, the study found. West Virginia had the highest rate (1.29 per person), followed by Kentucky, Tennessee, Louisiana, Alabama and Mississippi. The lowest prescription rates were seen in Alaska (0.52 prescriptions per person), followed by Oregon, Colorado, California and Washington state.

"The prescribing rate in the South was more than double the prescribing rate in the West," said Dr. Lauri Hicks, with the U.S. Centers for Disease Control and Prevention, adding that the research team would be "exploring the reasons behind those differences."

Health experts are interested in the rates, she said, "because antibiotic use is strongly linked to antibiotic resistance."

Among other research being presented at the conference, which concludes Sunday in Vancouver, Canada: three new drugs appear to show promise in fighting MRSA and other bacteria when current antibiotics fail.

  • Fusidic acid, which could fight S. aureus. "This is pretty exciting because it has no cross-resistance with any class of antibiotics so it could be used widely," said Dr. Ronald N. Jones, chief executive of JMI Laboratories in North Liberty, Iowa, which makes the drug and funded the study being presented.
  • JNJ-Q2. This potential agent belongs to a class of drugs known as fluoroquinolones and may be effective against S. aureus, including the methicillin-resistant form. "JNJ-Q2 was 16 times more potent than the existing marketed fluoroquinolones," Jones said. The drug is moving into phase 2 and phase 3 trials, he said.
  • A version of cephalosporin. It "may enable us to treat a broader spectrum of drug-resistant bacteria, although it probably won't be on the market till 2013 or 2014," Jones said.

Also being presented at the conference is a study involving a computer model that found that "universal contact precautions" -- requiring anyone visiting a MRSA patient in the hospital to wear gloves and a gown -- were more effective at preventing MRSA infection among patients in intensive-care units than were other strategies.

But the approach was expensive. The study's lead author, Dr. Courtney A. Gidengil, an instructor in pediatrics at Children's Hospital of Boston and Harvard Medical School, said that other strategies might be less effective but they are also less costly.

Another study presented at the conference found that carbapenem-resistant Enterobacteriaceae, or CRE, which carries a high mortality rate, is becoming more prevalent in the Chicago area.

More information

The CDC's Get Smart campaign has more on when antibiotics work and when they don't.

SOURCES: Oct. 22, 2010, teleconference with Lauri A. Hicks, D.O., medical director, Get Smart: Know When Antibiotics Work, U.S. Centers for Disease Control and Prevention; Courtney A. Gidengil, M.D., instructor, pediatrics, Children's Hospital of Boston and Harvard Medical School, and associate physician scientist, RAND Corporation, Boston; Ronald Jones, M.D., chief executive, JMI Laboratories, North Liberty, Iowa, and adjunct professor, medicine, Tufts University School of Medicine, Boston; Shu-Hua Wang, M.D., assistant professor, medicine, and medical director, Ben Franklin TB Control Program, Ohio State University, Columbus, Ohio, and medical TB consultant, Ohio Department of Health; presentations, annual meeting, Infectious Diseases Society of America, Oct. 21-24, 2010, Vancouver, British Columbia, Canada

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Childhood Obesity Might Be Linked to Strain of Cold Virus
2. H1N1 Pandemic Flu Even Milder Than Seasonal Strains
3. Emerging E. coli strain causes many antimicrobial-resistant infections in US
4. H1N1 Flu Vaccine May Shield Against 1918 Strain
5. New strain of bacteria discovered that could aid in oil spill, other environmental cleanup
6. Mount Sinai researchers approaching universal treatment for all strains of influenza
7. Prevalence of HIV in Africa is leading to new strains of Salmonella, say scientists
8. Flu Vaccine With Both B Strains May Offer Better Protection
9. Building a better flu vaccine: Add second strain of influenza B
10. Prompt actions halt alarming infection outbreak at Dallas hospital
11. Polio outbreak in Tajikistan is cause for alarm
Post Your Comments:
(Date:11/27/2015)... ... November 27, 2015 , ... According to an article published ... that they are handling security in light of the recent terrorist attacks in Paris, ... attempt to stop an attack from reaching U.S. soil. Especially around special events that ...
(Date:11/27/2015)... ... 2015 , ... A team of Swiss doctors has released a report on ... just posted the findings on the website. Click here to read the details ... mesothelioma patients who were treated with chemotherapy followed by EPP surgery. Among the 106 ...
(Date:11/27/2015)... ... November 27, 2015 , ... "When I was traveling, I ... Hillside, N.J. "Many people catch diseases simply from sitting on such dirty toilet ... protected from germs." , He developed the patent-pending QUDRATECS to eliminate the need ...
(Date:11/27/2015)... ... November 27, 2015 , ... The print component ... Today in Atlanta, Dallas, New York, Minneapolis, South Florida, with a circulation of ... distributed nationally, through a vast social media strategy and across a network of ...
(Date:11/27/2015)... ... November 27, 2015 , ... MPWH, the No.1 Herpes-only dating community in the world, ... Table 1-1 ). More than 3.7 billion people under the age of 50 – ... according to WHO's first global estimates of HSV-1 infection . , "The data shocks ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... November 26, 2015 ... addition of the  "2016 Future Horizons ... Therapeutic Drug Monitoring (TDM) Market: Supplier ... Emerging Opportunities"  report to their offering.  ... announced the addition of the  "2016 ...
(Date:11/26/2015)... DUBLIN , November 26, 2015 ... has announced the addition of the  ... in the European Cell Surface Marker ... Emerging Opportunities"  report to their offering.  ... announced the addition of the  "2016 ...
(Date:11/25/2015)...  Linden Care, LLC, a retail specialty pharmacy focused ... suffering from chronic pain, said today that it is ... (TRO) enjoining Express Scripts from unilaterally terminating the Pharmacy ... --> --> The company said that ... --> --> In ...
Breaking Medicine Technology: