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MRI techniques evolving towards better assessment of liver fibrosis
Date:1/2/2008

nitial studies but requires additional study for verification..

The authors emphasize that the design and conduct of high-quality diagnostic accuracy studies is essential for ongoing validation of these emerging non-invasive techniques for determining hepatic fibrosis. Most relevant studies to date have included small numbers of patients and lacked independent assessment, issues that should be addressed in future studies.

Once MRI techniques have become suitably advanced, patients will likely prefer them to liver biopsy. While the number of patients screened for hepatic fibrosis may increase using MR imaging, proof will be required that early detection and intervention can reduce morbidity and resource utilization associated with the clinical sequelae of advanced disease, the authors point out.

The development of a reliable and valid non-invasive method to assess hepatic fibrosis could result in comparable or, perhaps, improved accuracy in terms of staging, they conclude. The emergence of MR imaging techniques (singly or in combination with other methods) could result in the performance of true functional hepatic imaging.


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Contact: Amy Molnar
amolnar@wiley.com
Wiley-Blackwell
Source:Eurekalert

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