Navigation Links
MRI scans reveal brain changes in people at genetic risk for Alzheimer's
Date:12/16/2010

rain that make up what's called the default mode network," says lead author Yvette I. Sheline, MD. "In particular, we are interested in a part of the brain called the precuneus, which may be important in Alzheimer's disease and in pre-Alzheimer's because it is one of the first regions to develop amyloid deposits. Another factor is that when you look at all of the structural and functional connections in the brain, the most connected structure is the precuneus. It links many other key brain structures together."

The research team conducted functional MRI scans on 100 people whose average age was 62. Just under half of them carried the APOE4 variant, which is a genetic risk factor for late-onset Alzheimer's disease. Earlier PET scans of the study subjects had demonstrated that they did not have amyloid deposits in the brain. Amyloid is the protein that makes up the senile plaques that dot the brains of Alzheimer's patients and interfere with cognitive function.

Participants in the study also underwent spinal puncture tests that revealed they had normal amyloid levels in their cerebrospinal fluid.

"Their brains were 'clean as a whistle,' " says Sheline, a professor of psychiatry, of radiology and of neurology and director of Washington University's Center for Depression, Stress and Neuroimaging. "As far as their brain amyloid burden and their cerebrospinal fluid levels, these individuals were completely normal. But the people who had the APOE4 variant had significant differences in the way various brain regions connected with one another."

Sheline's team focused on the brain's default mode network. Typically, the default network is active when the mind rests. Its activity slows down when an individual concentrates.

Subjects don't need to perform any particular tasks for researchers to study the default mode network. They simply relax in the MRI scanner and reflect or daydream while the machine measures oxygen levels and bl
'/>"/>

Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine
Source:Eurekalert  

Page: 1 2 3 4 5

Related medicine news :

1. ER Patients Put Faith in CT Scans
2. CT Scans May Pose Less Cancer Risk Than Thought, Study Contends
3. Brain scans show effects of Parkinsons drug
4. CT Scans Seem to Lower Lung Cancer Death Rates
5. Helical CT scans reduce lung cancer mortality by 20% compared to chest X-rays
6. Scans Show How Hormone Levels Affect Female Brain
7. MRI, CT Scans for ER Patients Triple Over Decade
8. OHSU researchers able to determine brain maturity through analyzing MRI scans
9. Brain Scans Could Spot Developmental Problems in Kids
10. Dose optimization workshop helps reduce radiation dose associated with MDCT scans
11. Simple reduction technique decreases radiation dose associated with CT scans of the head
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MRI scans reveal brain changes in people at genetic risk for Alzheimer's
(Date:7/29/2015)... ... July 29, 2015 , ... One of the world’s ... on the potentially lifesaving impact of removing aluminum from Alzheimer’s disease patients, announced ... proposal is based on a successful pilot study published in The Journal of ...
(Date:7/29/2015)... ... July 29, 2015 , ... One may not expect to encounter a ... but that’s exactly what was happening on the campus of Piedmont Crossing , ... 4-year-olds from Kids Only , a five-star childcare center which operates on the ...
(Date:7/28/2015)... ... 2015 , ... Talking About Your Product Pipeline:, How FDA and SEC Regulate ... EDT, http://www.fdanews.com/productpipeline , When a company has a product in development, whether ... is tightly regulated by the FDA. , At the same time, the SEC requires ...
(Date:7/28/2015)... IL (PRWEB) , ... July 29, 2015 , ... The ... involvement of automakers. This would allow insurers to access the on-board vehicle data and ... been reticent when it comes to sharing vehicle data. However times are changing and ...
(Date:7/28/2015)... ... July 28, 2015 , ... A skin cancer screening program offered by ... of A award for “helping to make the world a better place.” , The ... by the American Society of Association Executives. Power of A recognizes organizations annually that ...
Breaking Medicine News(10 mins):Health News:Children's Medical Safety Research Institute Announces Innovative Study on Alzheimer’s Treatment Is Subject of Crowd Funding Campaign 2Health News:Children's Medical Safety Research Institute Announces Innovative Study on Alzheimer’s Treatment Is Subject of Crowd Funding Campaign 3Health News:North Carolina Retirement Community Re-Launches Intergenerational Programming with Onsite Daycare Center 2Health News:North Carolina Retirement Community Re-Launches Intergenerational Programming with Onsite Daycare Center 3Health News:North Carolina Retirement Community Re-Launches Intergenerational Programming with Onsite Daycare Center 4Health News:FDAnews Announces — Talking About Your Product Pipeline: How FDA and SEC Regulate Life Sciences Communications Webinar, Aug. 19, 2015 2Health News:FDAnews Announces — Talking About Your Product Pipeline: How FDA and SEC Regulate Life Sciences Communications Webinar, Aug. 19, 2015 3Health News:FDAnews Announces — Talking About Your Product Pipeline: How FDA and SEC Regulate Life Sciences Communications Webinar, Aug. 19, 2015 4Health News:General Motors Engaging Insurance Partners for the Connected Car 2Health News:General Motors Engaging Insurance Partners for the Connected Car 3Health News:ASDS Skin Cancer Program Honored 2Health News:ASDS Skin Cancer Program Honored 3
... Deficiency Notice Relating to Market Value , ... QC, Dec. 5 /PRNewswire-FirstCall/ - BELLUS Health Inc. (NASDAQ: ... light of continuing significant fluctuations in world capital markets, ... NASDAQ Capital Market, while continuing to maintain a full ...
... Boutique firm specializing in catastrophic injuries caused by medical negligence moves into ... ... December 5, 2008 -- The Law Offices of Christian A. Lodowski ... relocated to new office space in Towson., , ,The firm has moved ...
... "Company") (Nasdaq and MTA: CTIC) today announced that that its Board,of ... portion or all of five series of Convertible Notes (the "Notes") ... Senior Subordinated Notes due 2010, -- 5.75% Convertible ... Notes due 2010, -- 7.5% Convertible Senior Notes ...
... Without Harm and the World Health Organization today launched a global ... alternatives. , , The announcement came ... Mercury in Health Care, an event sponsored by the two organizations ... "This initiative aims to replace no less than 70 ...
... STINSON Brand Innovation, Inc.,announced that the brand consultancy has been awarded ... technology clients. , The honors include ... to logo design. , , Specifically, the ... eBioscience Logo Design (Gold), -- CSL Behring, Vivaglobin(R) ...
... your smile goes farther than you think , , THURSDAY, Dec. ... -- and so can happy friends of your friends. , ... you and people you,ve never met can have an impact ... beyond people we,re directly connected to," said study co-author James ...
Cached Medicine News:Health News:BELLUS Health is Preparing to Voluntarily Delist from the NASDAQ Capital Market 2Health News:BELLUS Health is Preparing to Voluntarily Delist from the NASDAQ Capital Market 3Health News:Law Offices of Christian Lodowski, Medical Malpractice Attorney, Relocates to New Office Park in Towson 2Health News:Cell Therapeutics, Inc. to Offer to Repurchase up to $124 Million of Its Notes 2Health News:Cell Therapeutics, Inc. to Offer to Repurchase up to $124 Million of Its Notes 3Health News:Health Care Without Harm, WHO Announce Partnership for Global Reduction of Mercury-Based Medical Devices 2Health News:STINSON Brand Innovation, Inc. Recognized With 8 Creative Awards 2Health News:Being Happy Affects Even Those You Don't Know 2Health News:Being Happy Affects Even Those You Don't Know 3
(Date:7/28/2015)... July 28, 2015 The Canadian ... the Canadian Anti-Fraud Centre (CAFC), continues ... using the CIPA verification seal on illegitimate pharmacy ... legitimate online pharmacy member companies who have maintained ... to more than 10 million Americans since 2002. ...
(Date:7/28/2015)... 28, 2015  Today, Sekisui Diagnostics announces the launch ... efficient instrument, with a broad menu of high quality ... the physicians, office or hospital laboratory. ... tests/hour with ISE, 72 patient sample on-board capability, minimizes ... assays (+3 ISE) to meet the testing needs of ...
(Date:7/28/2015)... the first virtual care solution to empower health care systems ... virtual care service line, announced an agreement with Group ... in use. ... As health systems consider how to ... providing their own branded online care for common medical conditions. ...
Breaking Medicine Technology:Canadian International Pharmacy Association (CIPA) Continues to Fight Rogues Fraudulently Using the Trusted CIPA Verification Seal 2Canadian International Pharmacy Association (CIPA) Continues to Fight Rogues Fraudulently Using the Trusted CIPA Verification Seal 3Sekisui Diagnostics Announces Launch of SK500 Clinical Chemistry System for US Laboratories 2Zipnosis Announces Group Health to use Virtual Care Service Line 2Zipnosis Announces Group Health to use Virtual Care Service Line 3
... for the High Speed Performance of ... for Additional Requirements and Information. VISUPAC ... with ophthalmologists. Important for routine operation ... short operating sequences. Extensive default settings ...
... Microscope with excellent maneuverability. Konan ... weight maintaining high quality. Easy ... by simply changing the adapter. ... has resulted in a sharp ...
... temporary implant for use with patients who ... dilator type 5S is a semicircular elastic ... pupil during phacoemulsification. It is supplied in ... Expansion of the pupil during phacoemulsification for ...
To maintain the conjunctival cul-de-sacs after enucleation or evisceration without hindering lid closure....
Medicine Products: