Navigation Links
MRI research demonstrates ALS attacks multiple parts of the brain
Date:9/16/2011

Recently published studies by a researcher in the Faculty of Medicine & Dentistry demonstrate that ALS known as Lou Gehrig's disease damages neurons in parts of the brain responsible for cognition and behaviour.

ALS, which stands for amyotrophic lateral sclerosis, is a fatal neurodegenerative disease that eventually leaves patients unable to move, breathe or swallow. Previous research has shown about 50 per cent of patients with ALS also have mild cognitive and behavioural changes, but between five and 15 per cent of patients can have severe changes resulting in dementia. In Canada, between 2,500 and 3,000 people live with the disease. Most die within two to five years of diagnosis.

Sanjay Kalra, a researcher in the faculty's Division of Neurology and a practising neurologist, has published two papers this year in the American Journal of Neuroradiology providing evidence that ALS affects more than just the motor cortex, the part of the brain responsible for motor function.

"ALS was previously thought to be a disease restricted to the motor system causing only weakness," says Kalra, the principal investigator in both peer-reviewed papers.

"But a significant proportion of people with ALS also have cognitive and behavioural changes. We wanted to know how ALS was impacting other parts of the brain to cause these symptoms.

"There is increasing evidence from pathological studies of ALS patients post-mortem that not just the motor system is involved. Our research supports this and demonstrates in those living with ALS, that the disease is indeed attacking other parts of the brain. The cognitive and behavioural changes we are seeing in patients are not reactive," he says. "They are not happening because someone is depressed or doesn't have initiative because he is weak. Those changes are happening because there are biological and chemical changes in parts of the brain that are responsible for behaviour and cognition." <
'/>"/>

Contact: Raquel Maurier
raquel.maurier@ualberta.ca
780-492-5986
University of Alberta Faculty of Medicine & Dentistry
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Embedded Mobile & M2M Device revenues to Rise to Almost $19 Billion Globally by 2014, Says Juniper Research
2. 2010 HSR Impact Award recognizes surgical safety research
3. MSU launches first anti-counterfeiting research program
4. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
5. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
6. Researchers discover new way to kill pediatric brain tumors
7. Family Research Council: Planned Parenthood Report Oversexualizes Ten-Year-Olds, Undermines Parental Authority
8. Michael J. Fox Foundation Awards $1 Million to Drive Critical New Research Tools and Technologies in Parkinsons Drug Development
9. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
10. International Diabetes Federation awards $2 million to 9 global diabetes research projects
11. Gladstones Robert Mahley to receive Research!America advocacy award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... Pittsburgh, PA (PRWEB) October 20, 2014 ... new, minimally-invasive procedure that enables physicians to repair a ... , The MitraClip system, developed by ... regurgitation (MR), a progressive and life-threatening condition in which ... allowing blood to flow backward from the heart’s left ...
(Date:10/20/2014)... hc1.com today announced the launch of ... enables healthcare organizations of all sizes to immediately ... management (“CRM”) solution. , Designed from the ground ... healthcare industry, the hc1 Healthcare Relationship Cloud™ personalizes ... combining healthcare CRM, HIPAA-compliant collaboration, and real-time analytics ...
(Date:10/20/2014)... October 20, 2014 AttorneyOne.com, a recognized authority ... information from the FDA on Sit and Slim II ... not to purchase or use Sit and Slim II because ... II is promoted as weight loss product on various websites ... the market in 2010 for safety reasons, can significantly increase ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 National Teen Driver ... of the American Academy of Pediatrics (Ohio AAP, http://www.ohioaap.org ... in encouraging parents of teen drivers to talk to their ... road. , Motor vehicle crashes are the leading cause of ... drivers involved in fatal crashes, and 859 (42%) of those ...
(Date:10/20/2014)... Houston plastic surgeon Dr. Christopher ... of his innovative True Form Tummy Tuck® ... and faculty at The University of Texas Medical ... once a medical student. Patronella, who is a founding ... surgery practices in Texas, The Aesthetic Center for ...
Breaking Medicine News(10 mins):Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 2Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 3Health News:Healthcare Relationship Management (HRM) Leader hc1.com® Launches hc1® Quick Start™ 2Health News:FDA Advises Not to Use Sit and Slim II: AttorneyOne Monitors and Keeps Consumers Informed 2Health News:Ohio AAP Promotes National Teen Driver Safety Week 2Health News:Plastic Surgeon Patronella Presents Artistically-Inspired Tummy Tuck Method to Future Generation of Plastic Surgeons in Texas 2
... cardiovascular diseases.,A potbelly indicates that the risk of a heart ... is skinny as a beanpole. ,This new study ... of waist size to the hips, an elevated waist-to-hip ratio ... that even people who would otherwise be considered safe going ...
... Women who exercise by doing household chores like dusting, ... cancer, suggests a new study.// ,The research ... from nine European countries and found that doing housework ... the online edition of BBC News. , ,It ...
... acquired but quite difficult to stop.// All habitual smokers who ... have to try out recommended smoking cessation methods. ... 16 and 24 years do try to quit smoking but ... methods. ,An article presented in Morbidity and Mortality ...
... undergo a double hand transplant was ecstatic as she got ... "I'm doing very well, I'm very happy. I'm taking steps ... life. When I saw the hands after the operation, they ... her arms following an explosion in a laboratory in 1978, ...
... that a flabby waist certainly points to a greater risk of ... study has revealed that the risk for coronary illness is inflated ... sports a podgy flabby waistline. ,The diameter along the median ... amounts to an imaginary line cutting through the body joining two ...
... government of Bharatiya Janta Party has been inspired from ... devise a family planning programme for the Muslim community// ... religious texts and clerics for awareness campaign as well ... comes in the way of family planning is ignorance ...
Cached Medicine News:Health News:Pot Belly Is A Better Risk Predictor Of Heart Attack Than BMI 2Health News:Tried To Quit Smoking And Failed? Call 1-800-QUIT-NOW 2Health News:Madhya Pradesh Imbibes Family Planning Lessons from Pakistan 2
(Date:10/17/2014)... 2014 According to ... Technique (Optical Coherence Tomography, Hyperspectral Imaging, Photoacoustic ... Neurology, Oncology, Cardiology) - Global Forecasts to ... Optical Imaging market over the forecast period ... $917.1 million in 2014 and is expected ...
(Date:10/17/2014)... 2014 The following is being released ... The Green Park Collaborative (GPC) will bring ... payers, medical device and pharmaceutical companies, as well ... 12, 2015 at its first ever workshop on ... treatments.  Participants will discuss study designs to evaluate ...
(Date:10/17/2014)... BALTIMORE , Oct. 17, 2014  Ameritox SM ... announced the appointment of Thomas Smith , M.D., ... lead a field-based team offering scientific resources for healthcare ... Smith has held leadership positions at a variety of ... will benefit both the pain and behavioral health sides ...
Breaking Medicine Technology:Optical Imaging Market Worth $1,669.2 Million by 2019 2Optical Imaging Market Worth $1,669.2 Million by 2019 3Optical Imaging Market Worth $1,669.2 Million by 2019 4Green Park Collaborative to Discuss Comparative Effectiveness and Value of Weight Loss Treatments 2Ameritox Appoints New Chief Medical Officer 2
... ... ... ... ...
... , ... ... ... ...
Cached Medicine Technology:BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 2BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 3BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 4BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 5BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 6BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 7BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 8BNA Books' Announces Publication of New 2009 Cumulative Supplement to 'Pharmaceutical Law: Regulation of Research, Development, and Marketing' 9China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 2China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 3China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 4China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 5China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 6China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 7China Biologic Products to Present at the Rodman & Renshaw Annual China Investment Conference 8
... The assay is an immunometric ... measurement of Prolactin in human ... the sample is bound by ... different epitopes. One antibody is ...
... hormone secreted in significant amounts by the ... in synergy with estrogen, plays an important ... of mammary gland growth and lactation in ... effects on cell growth in other tissues ...
... The AxSYM BNP assay allows ... in the status of your heart ... BNP versus NT-ProBNP. The AxSYM BNP ... fast, simple, walk-away resultson a platform ...
... this Enzyme ImmunoAssay (EIA) is as follows: ... on a 96 well microtiter plate. After ... the trapped molecule is covalently linked to ... After washing and denaturing treatment, Angiotensin II ...
Medicine Products: