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MRI predicts survival in locally advanced rectal cancer
Date:8/29/2011

her therapy prior to surgery. In some cases, the preoperative treatment removed all evidence of the tumor, leading some physicians to question the need for surgery. The investigators have begun a trial to study what happens to those individuals who appear to not have any remaining cancer with chemoradiation alone and have deferred surgery. In some cases, this has resulted in long-term deferral with anal sphincter preservation. Other trials may also be designed to use MRI results in regard to treatment efficacy.

ASCO Perspective: Morton Kahlenberg, MD, ASCO Cancer Communications Committee member and surgical oncology specialist

"This work has significant scientific and clinical importance because it shows that performing MRI following initial chemoradiation therapy and before surgery may predict long-term outcome and identify patients who could benefit from more aggressive therapy prior to surgery. This could change the standard of care for these patients, since using MRI may suggest the need for further treatment before surgery. Clinical trials are needed to address this important question."


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Contact: Nicole Fernandes
nicole.fernandes@asco.org
571-483-1354
American Society of Clinical Oncology
Source:Eurekalert

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