Navigation Links
MRI predicts liver fibrosis, study says
Date:10/23/2007

Moderate to severe chronic liver disease can be predicted with the use of diffusion-weighted MRI (DWI), according to a recent study conducted by researchers at New York University Medical Center in New York, NY.

Due to the increased incidence of chronic hepatitis in the United States, particularly hepatitis C, there is a strong need for non-invasive methods to replace or supplement liver biopsy, which is relatively invasive and limited by interobserver variability and sampling error, said Bachir Taouli, MD, lead author of the study. DWI appears promising in that purpose, although it needs validation in larger series, he said.

The study included 23 patients with chronic hepatitis and 7 volunteers. The researchers compared apparent diffusion coefficients (ADCs) or the quantification of water diffusion in a tissue between patients who had stage 2 or greater versus stage 1 or less fibrosis and stage 3 or greater versus stage 2 or less fibrosis. In liver fibrosis and cirrhosis, decreased ADC (i.e. restricted water diffusion) is possibly related to increased collagen deposition and decreased perfusion. The study showed that hepatic ADC was a significant predictor of stage 2 or greater and stage 3 or greater liver fibrosis.

At this point, this is an experimental method that needs to be tested in a larger series. It should also be compared with other methods such as FibroTest (a score based on a combination of basic serum markers) or FibroScan (an ultrasound based method to measure liver stiffness) in order to be validated, said Dr. Taouli. However, diffusion imaging does show potential for decreasing the number of biopsies and decreasing the number of antifibrogenic drug trials, he said.

We did not expect to have such good results in terms of detection of significant fibrosis, partly because this is an investigational study and we did not have any prior experience with such application, said Dr. Taouli.

This prelimina
'/>"/>

Contact: Necoya Lightsey
necoya@arrs.org
703-858-4304
American Roentgen Ray Society
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Restricted Activity Predicts Disability
2. Fitness Level Predicts Stroke
3. Atrial fibrillation predicts for acute ischaemic stroke
4. Weight and size at birth predicts mortality in adulthood
5. PSA Can Predicts The Treatment Response In Advanced Prostate Cancer
6. New Test Predicts CLL’s Sensitivity to Experimental Drug
7. Being Teased Predicts Poor Psychological Functioning in Youth With Cleft Lip
8. Model Predicts Colon Cancer Inheritable Genetic Defects
9. Formula Predicts Osteoporotic Fracture Risk
10. Computer Tool Predicts Effectiveness Of Microbicides
11. New Genetic Test Predicts Eye-Cancer Patients Futures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... (PRWEB) , ... July 30, ... ... released a video, “Beachside Nursing Center,” to announce its position as one ... ratings. Beachside's administrator and staff members support the CMS rating system, which ...
(Date:7/30/2015)... ... July 30, 2015 , ... Zejax ... New Tool That Increases Training Capability , World renown body weight trainer, ... ( http://www.Zejax.com ), that dramatically increases a person’s training capability. , The American ...
(Date:7/30/2015)... ... 2015 , ... Boston Web Marketing is proud ... Partners is the platform for search marketing agencies to communicate with the Google ... to run successful search marketing campaigns. Google Partners also affords businesses the opportunity ...
(Date:7/30/2015)... ... July 30, 2015 , ... Gummy smile surgeon, Dr. Alex ... and surgery, as well as the patented gum depigmentation treatmet. Dr. Farnoosh is a ... with many patients from around the world. , “Like treatment of any other disease ...
(Date:7/30/2015)... ... , ... InventHelp, a leading inventor service company, announces that one ... it easy to apply lotion or medication to a hard-to-reach area. This invention is ... or medication to the back, and provides thorough coverage. The product would prevent the ...
Breaking Medicine News(10 mins):Health News:Beachside Nursing Center Releases New Video 2Health News:Zejax is a Revolutionary New Way of BodyWeight Training Without Weights 2Health News:Boston Web Marketing Attends Google Partners All-Stars Summit 2Health News:Gummy Smile Dentist, Alex Farnoosh DMD, is Now Offering Comprehensive Treatment Options for Gummy Smiles 2Health News:InventHelp® Client Patents “My Back Buddy” – Device Could Apply Lotion to Hard-to-Reach Areas Easily 2
... In a case of dubious consolation, nineteen persons infected ... making this Chinas most moneyed lawsuit//. This money should ... as most of them are living in poverty. ... operations carried out at a provincial hospital of northern ...
... of Neurological disorders in their early stage or ... ,Melbourne researchers have found a relationship between ... roses and bleach and neurological disorders such as ... of the Melbourne Neuropsychiatry Clinic, Christos Pantelis said, ...
... Institute have found a protein that causes a brain wasting ... effects// the regulation of glucose in the blood stream. ... direct effect of the disease on the regulatory mechanism of ... in the blood is found as a twisted, deformed protein ...
... to multiple dogs along with presence of a certain ... says a new study//., ,David Bernstein, professor of ... found this after studying about 500 infants, reported online ... is associated with a higher risk of developing allergies ...
... that spanned over 3 decades was conducted by Danish ... risk of mental illnesses such as schizophrenia,// depression, or ... children were seldom seen admitted in psychiatric wards. Statistics ... risk than those who do not have children. ...
... started creating an online global map called as ‘Malaria Atlas ... the// areas where the disease is most likely to strike. ... supporting the project. ,It is reported that every ... per cent of the world's population is at risk of ...
Cached Medicine News:Health News:Detection of Neurological Disorder is Just a Sniff Away!! 2Health News:Juvenile Diabetes may Be Caused by Mad Cow Protein 2
(Date:7/29/2015)... PLEASANTON, Calif. , July 30, 2015 ... it has submitted the cobas® EGFR Mutation Test ... Food and Drug Administration (FDA), as a companion ... for non-small cell lung cancer patients with an ... non-small cell lung cancer who have adenocarcinoma with ...
(Date:7/29/2015)... , July 29, 2015 Dignity Health ... Orthopedic Institute, combining the services of the hospital,s former ... one centralized location, and expanding services to include shoulder ... street from Saint Francis Memorial Hospital at 1199 Bush ... is a premier center aimed at providing a continuum ...
(Date:7/29/2015)... 2015  Unilife Corporation ("Unilife" or the "Company") (NASDAQ: ... and supplier of injectable drug delivery systems, today announced ... the Company with flexibility and control to support its ... an equity purchase agreement for up to $45 million ... Chicago -based institutional investor, which provides the ...
Breaking Medicine Technology:Roche submits filing to FDA for companion diagnostic for non-small cell lung cancer drug therapy 2Roche submits filing to FDA for companion diagnostic for non-small cell lung cancer drug therapy 3Saint Francis Memorial Hospital Orthopedic Institute Offers Comprehensive Orthopedic Care in One Location 2Unilife Announces Multifaceted Financing Strategy 2Unilife Announces Multifaceted Financing Strategy 3Unilife Announces Multifaceted Financing Strategy 4Unilife Announces Multifaceted Financing Strategy 5
... response to outbreaks of swine flu across North ... service, has issued professionally-written influenza notification scripts for ... protect the millions of families currently receiving One ... announced a NO-Charge, proactive emergency calling plan for ...
... two prospective, double-blind placebo controlled multi-center studies in patients ... and safety data in patients with focal dystonia and ... American Academy of Neurology,s (AAN) 61st annual meeting in ... which plans to file a Biologic License Application (BLA) ...
Cached Medicine Technology:One Call Now Offers Notification Service at NO CHARGE for Governments, Schools, Businesses, Religious Organizations and Others in Response to Swine Flu Outbreak 2One Call Now Offers Notification Service at NO CHARGE for Governments, Schools, Businesses, Religious Organizations and Others in Response to Swine Flu Outbreak 3Merz Pharmaceuticals Announces Results of Three Clinical Trials With NT-201 (Botulinum Neurotoxin Type A Free From Complexing Proteins) in Movement Disorder Patients 2Merz Pharmaceuticals Announces Results of Three Clinical Trials With NT-201 (Botulinum Neurotoxin Type A Free From Complexing Proteins) in Movement Disorder Patients 3Merz Pharmaceuticals Announces Results of Three Clinical Trials With NT-201 (Botulinum Neurotoxin Type A Free From Complexing Proteins) in Movement Disorder Patients 4Merz Pharmaceuticals Announces Results of Three Clinical Trials With NT-201 (Botulinum Neurotoxin Type A Free From Complexing Proteins) in Movement Disorder Patients 5
... Our breadth of infectious disease ELISA products ... With standard assay protocols for faster integration ... ELISA products provide increased reliability and run-to-run ... antibody detection assays for a wide range ...
... Our breadth of infectious disease ELISA ... field. With standard assay protocols for faster ... Disease ELISA products provide increased reliability and ... includes antibody detection assays for a wide ...
... breadth of infectious disease ELISA products make ... standard assay protocols for faster integration into ... products provide increased reliability and run-to-run consistency. ... detection assays for a wide range of ...
... Our breadth of infectious disease ELISA ... field. With standard assay protocols for faster ... Disease ELISA products provide increased reliability and ... includes antibody detection assays for a wide ...
Medicine Products: