Navigation Links
MRI may help determine time of stroke onset
Date:11/1/2010

OAK BROOK, Ill. Magnetic resonance imaging (MRI) of the brain could expand the number of stroke patients eligible for a potentially life-saving treatment, according to a new study, published online and in the December issue of the journal Radiology.

Some patients who suffer an acute ischemic stroke in which a blood clot or other obstruction blocks blood flow in the brain can be treated with a drug called tissue plasminogen activator, or tPA, that dissolves the clot and restores blood flow. However, the clot-busting drug can only be administered within four and a half hours of the onset of a stroke; when given beyond that window of time, the drug can cause bleeding in the brain.

According to the American Stroke Association, stroke is the third leading cause of death in the United States behind diseases of the heart and cancer. Approximately 795,000 Americans suffer a new or recurrent stroke each year.

"As many as a quarter of all stroke patients cannot be given tPA because they wake up with stroke symptoms or are unable to tell their doctor when their stroke began," said lead researcher Catherine Oppenheim, M.D., Ph.D., professor of radiology at Universit Paris Descartes in France.

In the study, Dr. Oppenheim and her team of researchers reviewed data from consecutive patients with acute ischemic stroke treated at Sainte-Anne Hospital in Paris between May 2006 and October 2008. The time of stroke onset was well defined in all patients and each underwent MRI within 12 hours.

The 130 patients in the study included 77 men and 53 women (mean age 64.7). Of those, 63 patients underwent MRI within three hours of stroke onset and 67 were imaged between three and 12 hours after stroke onset.

The radiologists analyzed different types of MRI data on the patients, including fluid-attenuated inversion recovery (FLAIR), diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) ratios.

Using the MRI data alone, the radiologists were able to predict with greater than 90 percent accuracy which patients had experienced stroke symptoms for longer than three hours.

"When the time of stroke onset is unknown, MRI could help identify patients who are highly likely to be within the three-hour time window when tPA is proven effective and approved for use," Dr. Oppenheim said.

According to Dr. Oppenheim, using MRI to determine the duration of a stroke would change the way stroke is managed in the emergency setting.

"With the use of MRI, all stroke patients could be managed urgently, not just those patients with a known onset of symptoms," she said.

Dr. Oppenheim said clinical trials are the next step necessary to validate the use of MRI as a surrogate marker of stroke duration.


'/>"/>

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Related medicine news :

1. UT Southwestern study to determine whether leptin helps type 1 diabetes patients
2. For sufferers of an early-onset dementia, career choice may determine location of disease in brain
3. OHSU researchers able to determine brain maturity through analyzing MRI scans
4. Micro-RNA determines malignancy of lung cancer
5. Location determines social network influence, CCNY-led team finds
6. Can I buy you a drink? Genetics may determine sensitivity to other peoples drinking behavior
7. Delivery Method May Determine the Bacteria Babies Acquire
8. New possibility to determine the severity of appendicitis
9. Tongue measurements may help dentists determine oral appliance therapy success for sleep apnea
10. Strategy to help doctors determine when to treat retinopathy of prematurity
11. How, When Child Develops Autism May Determine Outcomes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2017)... ... 28, 2017 , ... Florida Pain Relief Group, a division ... M.D., has joined its new Melbourne pain clinic. , Dr. Fernandez-Silva’s practice ... techniques to treat and manage many types of pain. , Dr. Fernandez-Silva ...
(Date:5/27/2017)... ... May 27, 2017 , ... In any business, follow ... the talent of your dental team at presenting treatment, there will always be some ... lot of time and money on best practices when it comes to presenting treatment. ...
(Date:5/26/2017)... ... May 26, 2017 , ... Leading CEOs from ... May 30th and 31st at The Four Seasons Hotel Boston. , The ... life sciences, offering exclusive access to key decision makers who influence deal making ...
(Date:5/26/2017)... SARASOTA, Fla. (PRWEB) , ... May 26, 2017 ... ... providers of premium delicatessen foods, is sharing bold recipes for Memorial Day entertaining ... to your menus. , “Boar’s Head fresh sliced meats and cheeses featured ...
(Date:5/26/2017)... ... 2017 , ... Silver Birch of Hammond, a new assisted lifestyle community, has ... acres of land at 5620 Sohl Avenue in Hammond, serves older adults who need ... studio and one-bedroom apartments. Each of the private apartments at Silver Birch features a ...
Breaking Medicine News(10 mins):
(Date:5/12/2017)... 2017  The China and Canada joint ... less water, energy and detergent, and features a powerful disinfection process. ... shoebox-sized washing machine that washes and sanitizes women,s panties or babies, ... ... and does not require an external water inlet. ...
(Date:5/10/2017)... MARLBOROUGH, Mass., May 10, 2017 Hologic, Inc. ... financial results for the fiscal second quarter ended April ... (EPS) of $1.84 increased 666.7% compared to the prior ... business resulted in a significant gain, while non-GAAP diluted ... increased 3.2%, or 3.8% in constant currency terms.  Excluding ...
(Date:5/10/2017)... , May 10, 2017  The Corporate ... or employees of sleep therapy clinics to call ... sleep therapy clinic is involved in a substantial ... interested in hearing from an employee of a ... in a kickback scheme to provide medical practice groups ...
Breaking Medicine Technology: