Navigation Links
MRI findings help forecast prostate cancer prognosis
Date:3/24/2008

OAK BROOK, Ill. Magnetic resonance imaging (MRI) findings in patients about to undergo radiation therapy for prostate cancer can help predict the likelihood that the cancer will return and spread post-treatment, according to a new study published in the April issue of the journal Radiology.

This is the first study to show that MRI detection and measurement of the spread of prostate cancer outside the capsule of the prostate is an important factor in determining outcome for men scheduled to undergo radiation therapy, said study co-author Fergus V. Coakley, M.D., professor of radiology and urology, vice chair for clinical services and section chief of abdominal imaging in the Department of Radiology at University of California, San Francisco.

Prostate cancer forms in tissues of the prostate, a gland in the male reproductive system. The National Cancer Institute estimates 186,320 new cases of prostate cancer will be diagnosed in the U.S. in 2008, mostly in men over age 65. When diagnosed and treated early, the five-year survival rate for patients with prostate cancer is nearly 100 percent. However, once the cancer spreads or recurs beyond the prostate, the chance of survival drops significantly.

One common treatment for prostate cancer is external beam radiation therapy. Dr. Coakley and colleagues sought to determine if MRI findings prior to radiation therapy were an indicator of possible recurrence and spread.

The researchers retrospectively reviewed the MR images of 80 men with prostate cancer who had undergone MRI of the prostate prior to external beam radiation therapy. Details of tumor characteristics, treatment and outcome were recorded. Using a Cox regression analysisa technique that correlates the relationship between survival of a patient and several contributing variables, the researchers determined that the presence and degree of extracapsular extension (spread of cancer beyond the membrane that surrounds the prostate gland) seen on the pre-treatment MR images was an important predictor of post-treatment recurrence and spread. Specifically, patients with extracapsular extension greater than 5 millimeters (about the diameter of a pencil eraser) were more likely to experience recurrence and spread of their cancers.

Patients with substantial extracapsular spread of prostate cancer may wish to discuss options for more aggressive therapy with their treating physicians, Dr. Coakley said.


'/>"/>

Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Related medicine news :

1. MHA to Release Findings of Independent Long Term Care Member Study
2. New findings about the brain lead to treatment for eating disturbances
3. New Findings Support Alternatives to Pap Test
4. DNA Findings Reveal Genetic History of Humans
5. New findings on emerging contaminants
6. Research findings may lead to new ways to study and fight diabetes
7. A Sneak Peek Into the Special Needs Home of Tomorrow - Renowned Autism Consultant Valerie Herskowitz to Present Latest Findings at Autism Through the Lifespan Conference February 14-17 in Orlando
8. New findings contradict a prevailing belief about the inner ear
9. NeoStrata Clinical Findings Reveal Benefits of Combining Glycolic Acid Peels and Targeted Home Care With Microdermabrasion for Optimized Treatment of Photodamaged Skin
10. MarketResearch.com Distributes Key Findings on Global Specialty Medical Beds and Therapeutic Surfaces Market
11. New findings show Enbrel significantly reduced levels of C-reactive protein
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... ... January 20, 2017 , ... "TransFlare 4K Mystique comes with 44 colorful ... Pro X," said Christina Austin - CEO of Pixel Film Studios. , TransFlare ... Sensor,TransFlare 4K Mystique lens flare and light leak transitions have a very high-dynamic range ...
(Date:1/20/2017)... , ... January 20, 2017 , ... “Code Word: Chocolate Biscuit”: a biographical account following ... Chocolate Biscuit” is the creation of published author, Marlyn Ivey, born in Lynn Haven, Florida ... went to school and at 19 years of age, he joined the Navy and got ...
(Date:1/20/2017)... (PRWEB) , ... January 20, 2017 , ... “Journey to Christmas:” a beautiful and enchanting ... of published author, Kimberly Cordoves, a mother of three in Oklahoma City, and a devoted ... idea of writing a book has been in the back of my mind for years, ...
(Date:1/19/2017)... ... ... Today, the Centers for Medicare & Medicaid Services (CMS) announced over 359,000 ... in 2017. Clinicians who participate in APMs are paid for the quality of care ... effort to build a system that delivers better care and one in which clinicians ...
(Date:1/19/2017)... ... ... cold weather here, many people will have to clear snow with snow blowers or shovels ... but they can be dangerous when used incorrectly. That’s why Amica Insurance is ... of snow blowers:, , When removing wet snow or debris from ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... Jan. 19, 2017  Sensus Healthcare, Inc. (NASDAQ: ... specializing in the treatment of non-melanoma skin cancers ... superficial radiation therapy, today announced that it will ... financial results on Thursday, February 2, 2017 after the ... a conference call with the investment community on Thursday, ...
(Date:1/19/2017)... , Jan. 19, 2017   Science Exchange , ... to announce that the first five replication studies ... have been published in eLife today. Despite intense ... the first practical evaluation of reproducibility rates that ... studies. Unlike other assessments of reproducibility, the results ...
(Date:1/19/2017)... PALM BEACH, Florida , January 19, 2017 ... the incoming Trump administration appears serious about reducing ... boost advancements and innovation in the medical drug ... companies forge ahead with new clinical trials and ... and Pharma companies forging ahead with recent developments ...
Breaking Medicine Technology: