Navigation Links
MRI catches breast cancer early in at-risk survivors of childhood Hodgkin lymphoma
Date:5/28/2014

(TORONTO, Canada May 28, 2014) The largest clinical study to evaluate breast cancer screening of female survivors of childhood Hodgkin lymphoma (HL), who are at increased risk because they received chest radiation, shows that magnetic-resonance imaging (MRI) detected invasive breast tumours at very early stages, when cure rates are expected to be excellent.

The finding, published online today in the American Cancer Society Journal Cancer (doi: doi/10.1002/cncr.28747), underscores the need for at-risk childhood HL survivors and primary care physicians to be aware of established guidelines that recommend breast MRI screening from the age of 25 years or eight years following chest radiation (whichever is later), says principal investigator Dr. David Hodgson, a radiation oncologist at Princess Margaret Cancer Centre, University Health Network.

Dr. Hodgson, also an Associate Professor, Faculty of Medicine, University of Toronto, talks about the research: https://www.youtube.com/watch?v=HH68rItcRyU.

"Female survivors of childhood HL who had chest radiation should speak with their family doctor about after-care assessment and breast cancer screening" says Dr. Hodgson.

"We estimate that 75% of women who are at high risk because of prior radiotherapy to the chest are not being screened. So my hope is that this new evidence will encourage these survivors to discuss early screening with their doctors.There is a provincial pediatric oncology aftercare system already in place to help them, organized by the Pediatric Oncology Group of Ontario (POGO)."

Dr. Hodgson's study team, in collaboration with colleagues at the Dana Farber Cancer Institute in Boston, performed 274 breast MRI screens on 96 women from 2005 to 2012. Ten breast cancers half of them invasive tumors were diagnosed in nine women during 363 person-years follow up. The median age of breast cancer diagnosis was 39 years (range 24 to 43 years), and the median latency period between HL diagnosis and age at breast cancer diagnoses was 21 years (range 12 to 27 years). "This illustrates the young age at which these cancers can occur. For some of these women, if they had been screened starting at age 40 or 50 like average risk women, it would have been too late."

Of the 10 detected breast tumours, five were visible on both MRI and mammogram; three were visible only on MRI; and two were detected on mammogram alone (but were non-invasive). The median size of invasive tumors size was 8mm (range 3-15mm) and none had spread to the lymph nodes. These results are substantially better than prior studies using only mammographic screening in these young patients, in which almost half of the cancers detected had cancer spread to lymph nodes. Dr. Hodgson points out that because MRI screening is so much more sensitive to small changes in the appearance of the breast tissue than mammography, up to a third of patients may be called back for further testing of suspicious findings, many of which are benign or not clinically significant and therefore require no treatment. "It's important to forewarn at-risk HL survivors because call backs definitely heighten anxiety."


'/>"/>

Contact: Jane Finlayson
jane.finlayson@uhn.ca
416-946-2846
University Health Network
Source:Eurekalert  

Related medicine news :

1. Health care safety net catches suburban poor
2. They’re Back: Web Cam Catches Sockeye Salmon Returning to Tongass Spawning Grounds
3. Seva Call Launches in KC to Get Great Catches on the Line for Missouri River Consumers and Businesses
4. Study identifies risk of chemotherapy related hospitalization for eary-stage breast cancer patients
5. Researchers identify a new suppressor of breast metastasis to the lung
6. Two new possible drug targets for triple negative breast cancer
7. SLU virologists harness adenovirus to kill breast cancer cells
8. Yale Cancer Center studies find lifestyle changes improve biomarkers for breast cancer recurrence and mortality
9. Signals found that recruit host animals cells, enabling breast cancer metastasis
10. Breastfeeding initiation and success is impacted by diabetes status of mother
11. Cognitive behavioral or relaxation training helps women reduce distress during breast cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MRI catches breast cancer early in at-risk survivors of childhood Hodgkin lymphoma
(Date:5/31/2016)... ... May 31, 2016 , ... TeaZa® Energy, LLC announces the launch ... World No Tobacco Day . The new flavor—Tropical TeaZa? Energy—will be available to ... , The new flavor is best described as a juicy, taste bud takeover. ...
(Date:5/31/2016)... ... , ... Dr. Charles A. Ditta attained his Doctor of Medical Dentistry Degree ... 1986, where he graduated in the top ten percentile of his class. Dr. Ditta ... He has been a member in good standing for thirty years in the American ...
(Date:5/31/2016)... ... 2016 , ... CURE Media Group , the nation’s ... Cancer and Careers to its Advocacy Spotlight Partnership program ... careers while fighting cancer. , As partners, both organizations will supply timely information ...
(Date:5/30/2016)... ... May 30, 2016 , ... "This plugin comes with ... Austin - CEO of Pixel Film Studios. , TransPack Volume 7 features ... Choose from abstract transitions to more simple wipes with blur & drop shadow ...
(Date:5/30/2016)... ... May 30, 2016 , ... Another ER facility operated by ... at 3960 Legacy Drive, Plano, TX and is open 24 hours daily. , First ... by a medical open house. The Jasper High School band entertained attendees and accepted ...
Breaking Medicine News(10 mins):
(Date:5/31/2016)... May 31, 2016  Diplomat Pharmacy, Inc. (NYSE: ... that Phil Hagerman , Chairman & CEO, and ... Blair 36 th Annual Growth Stock Conference in ... Mr. Whelan are scheduled to present at the conference on ... live audio-only webcast of the presentation and related presentation materials ...
(Date:5/31/2016)... COTTAGE, New York , May 31, 2016 /PRNewswire/ ... as an essential ingredient in food, cosmetics and pharmaceuticals, ... end, representing revenues worth US$ 1.6 Bn. ... gels, cosmetics products, juices, and yogurts will continue its ... and wellness trend will also boost positive sentiment on ...
(Date:5/31/2016)... 2016 , Isansys  Lifecare, a new ... Status Engine wireless patient monitoring platform, as it ships more ... Germany , Scotland and ... generation system, launched earlier this year, is now being used ... , This new technology significantly enhances the user ...
Breaking Medicine Technology: