Navigation Links
MRI catches breast cancer early in at-risk survivors of childhood Hodgkin lymphoma
Date:5/28/2014

(TORONTO, Canada May 28, 2014) The largest clinical study to evaluate breast cancer screening of female survivors of childhood Hodgkin lymphoma (HL), who are at increased risk because they received chest radiation, shows that magnetic-resonance imaging (MRI) detected invasive breast tumours at very early stages, when cure rates are expected to be excellent.

The finding, published online today in the American Cancer Society Journal Cancer (doi: doi/10.1002/cncr.28747), underscores the need for at-risk childhood HL survivors and primary care physicians to be aware of established guidelines that recommend breast MRI screening from the age of 25 years or eight years following chest radiation (whichever is later), says principal investigator Dr. David Hodgson, a radiation oncologist at Princess Margaret Cancer Centre, University Health Network.

Dr. Hodgson, also an Associate Professor, Faculty of Medicine, University of Toronto, talks about the research: https://www.youtube.com/watch?v=HH68rItcRyU.

"Female survivors of childhood HL who had chest radiation should speak with their family doctor about after-care assessment and breast cancer screening" says Dr. Hodgson.

"We estimate that 75% of women who are at high risk because of prior radiotherapy to the chest are not being screened. So my hope is that this new evidence will encourage these survivors to discuss early screening with their doctors.There is a provincial pediatric oncology aftercare system already in place to help them, organized by the Pediatric Oncology Group of Ontario (POGO)."

Dr. Hodgson's study team, in collaboration with colleagues at the Dana Farber Cancer Institute in Boston, performed 274 breast MRI screens on 96 women from 2005 to 2012. Ten breast cancers half of them invasive tumors were diagnosed in nine women during 363 person-years follow up. The median age of breast cancer diagnosis was 39 years (range 24 to 43 years), and the median latency period between HL diagnosis and age at breast cancer diagnoses was 21 years (range 12 to 27 years). "This illustrates the young age at which these cancers can occur. For some of these women, if they had been screened starting at age 40 or 50 like average risk women, it would have been too late."

Of the 10 detected breast tumours, five were visible on both MRI and mammogram; three were visible only on MRI; and two were detected on mammogram alone (but were non-invasive). The median size of invasive tumors size was 8mm (range 3-15mm) and none had spread to the lymph nodes. These results are substantially better than prior studies using only mammographic screening in these young patients, in which almost half of the cancers detected had cancer spread to lymph nodes. Dr. Hodgson points out that because MRI screening is so much more sensitive to small changes in the appearance of the breast tissue than mammography, up to a third of patients may be called back for further testing of suspicious findings, many of which are benign or not clinically significant and therefore require no treatment. "It's important to forewarn at-risk HL survivors because call backs definitely heighten anxiety."


'/>"/>

Contact: Jane Finlayson
jane.finlayson@uhn.ca
416-946-2846
University Health Network
Source:Eurekalert  

Related medicine news :

1. Health care safety net catches suburban poor
2. They’re Back: Web Cam Catches Sockeye Salmon Returning to Tongass Spawning Grounds
3. Seva Call Launches in KC to Get Great Catches on the Line for Missouri River Consumers and Businesses
4. Study identifies risk of chemotherapy related hospitalization for eary-stage breast cancer patients
5. Researchers identify a new suppressor of breast metastasis to the lung
6. Two new possible drug targets for triple negative breast cancer
7. SLU virologists harness adenovirus to kill breast cancer cells
8. Yale Cancer Center studies find lifestyle changes improve biomarkers for breast cancer recurrence and mortality
9. Signals found that recruit host animals cells, enabling breast cancer metastasis
10. Breastfeeding initiation and success is impacted by diabetes status of mother
11. Cognitive behavioral or relaxation training helps women reduce distress during breast cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
MRI catches breast cancer early in at-risk survivors of childhood Hodgkin lymphoma
(Date:3/24/2017)... FL (PRWEB) , ... March 24, 2017 , ... ... Inc. ( http://www.hygieacare.com ) announced their partnership to prep patients for colonoscopy at ... Endoscopy Centers in 87th Ave., Miami, FL. , The HyGIeaCare® ...
(Date:3/24/2017)... ... March 24, 2017 , ... “Finding Christ Through ... a devotional journal chronicling the writer’s path toward true communion with God. “Finding ... God #TruthwithGrace” is the creation of published author Lea Michelle Johnson, a follower ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... stories about real people of God in congregations across the United States. ... Presbyterian minister ordained in 1964 who has served congregations in seven states throughout ...
(Date:3/23/2017)... ... 23, 2017 , ... A recent report from the National Council on Teacher ... NCTQ report suggests, based on a review of GPA and SAT/ACT requirements at 221 ... the U.S. It argues that this higher bar should be set by states, by ...
(Date:3/23/2017)... ... 23, 2017 , ... Texas Physical Therapy Specialists (TexPTS) is pleased to ... 2. The clinic is the group’s second in New Braunfels and 22nd in Texas. ... New Braunfels location brings things full circle for the group, “It’s crazy to think ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... , March 24, 2017 New England ... recipient of an award including funding and in-kind service ... draw technology.  "Making blood draws less ... making their whole hospital experience better.  We,re looking forward ... technology can help improve care for the kids we ...
(Date:3/24/2017)... YORK , March 24, 2017   ... leading organization within medical affairs in the pharmaceutical ... as the chair of a newly formed scientific ... board members to form the first ever medical ... For more information about the ACMA, please ...
(Date:3/24/2017)... Research and Markets has announced the addition ... - 2035" report to their offering. ... The Deep Learning: Drug Discovery and Diagnostics ... the growing market of deep learning solutions within the healthcare domain. ... emerged as a novel solution to generate relevant insights from medical ...
Breaking Medicine Technology: