Navigation Links
MRI and PET/CT improve cervical cancer patient's chances for optimal treatment
Date:3/3/2009

Pretreatment MRI and PET/CT for cervical cancer may direct more women to optimal therapy choices and spare many women potential long-term morbidity and complications of trimodality therapy (surgery followed by chemoradiation), according to a study performed at the Institute for Technology Assessment in Boston, MA.

An interdisciplinary team of investigators developed a decision-analytic model to determine the value of pretreatment imaging with MRI and/or PET/CT in patients with FIGO Stage IB cervical cancer. "Stage IB cervical cancer, in the absence of pre-treatment imaging, is treated with surgery. As surgery cannot completely resect the cancer in many of these patients, they receive post-surgical chemoradiation, i.e. trimodality therapy," said Pari Pandharipande, MD, lead author of the study. "The goal of pre-treatment imaging is to identify these patients noninvasively, spare them surgery and have them treated with chemoradiation alone," she said. Study results showed that while imaging does not improve survival, PET/CT resulted in the highest percentage of patients receiving correct primary therapy (89%) and use of both MRI and PET/CT spared the most patients of trimodality therapy (95%).

"Pretreatment imaging can triage patients to optimal primary treatment choices that minimize the risk of long-term complications and morbidity while preserving chances for survival," said Dr. Pandharipande. "Because both over- and underestimation of disease extent can result in adverse patient outcomes, determining the extent of disease accurately up front is critical. For example, when patients are subjected to pelvic surgery, and then are radiated in the same operative field, complication rates can increase by a substantial percentage, as compared to if they were simply treated with surgery alone or chemoradiation alone. Our study shows how pre-treatment imaging may improve chances of correctly receiving surgery or chemoradiation instead of both," said Dr. Pandharipande.

"MRI and PET/CT are expensive, but long-term consequences of trimodality therapy can severely affect long-term quality of life and are also expensive. Further study of these long-term consequences is needed to more precisely consider the cost implications of upfront MRI and PET/CT," she said.

"Currently there are no specific guidelines that prescribe MRI or PET/CT for determining a plan of action for the treatment of stage IB cervical cancer patients. It remains important for patients to make imaging and treatment decisions with their gynecologic-oncologist on a case-by-case basis," said Dr. Pandharipande.

"My goal as a researcher in radiology is to continue to objectively look at what we do and how it impacts patient care. A better understanding of what happens to people after they receive imaging tests both improves patient care directly and focuses further research efforts in areas most influential to patient outcomes," she said.


'/>"/>

Contact: Heather Curry
hcurry@arrs.org
703-858-4304
American Roentgen Ray Society
Source:Eurekalert

Related medicine news :

1. PET/CT may improve prognosis for patients with inflammatory breast cancer
2. PET/CT scan could be valuable noninvasive tool for determining stages of ovarian cancer
3. MRI and PET/CT can prevent unnecessary treatment of some cervical cancer patients
4. PET/CT planning beneficial for head and neck cancer patients
5. Combo PET/CT Scan Helps Spot Breast Cancers Spread
6. PET/CT brings new hope to patients with deadly form of breast cancer
7. PET/CT Brings New Hope to Patients With Deadly Form of Breast Cancer
8. 18F-DG PET/CT can highly increase the detection of colorectal cancer
9. Zebra Technologies Introduces New Soft Infant Wristbands for Improved Safety and Comfort
10. CVS Caremark Health Management Programs Help Multiple Sclerosis Patients Better Manage Weight Issues and Improve BMI
11. VHA Selects Clinical Xpert from Thomson Reuters as its Preferred Solution for Mobile Clinical Improvement Systems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/18/2017)... ... 2017 , ... Floundering on New Year’s resolutions? Need an excuse to get ... reset. The U.S. Apple Association agrees and recommends starting each day with apples, ... to heart disease. , The U.S. Apple Association – which represents apple growers and ...
(Date:1/17/2017)... ... January 17, 2017 , ... In the crowded Ath-leisure market, ... stand-out company for several differences from other mainstream brands. , Firstly, in ... is called 'Agile' manufacturing - http://www.leanproduction.com/agile-manufacturing.html . It allows them to have ...
(Date:1/17/2017)... (PRWEB) , ... January 17, 2017 , ... SunView Software’s ... Award for Innovation of the Year. , Each year, Pink Elephant recognizes ... an innovative approach to address a specific business problem or opportunity. The award highlights ...
(Date:1/17/2017)... Clemente, CA (PRWEB) , ... January 17, 2017 ... ... Diego County, as well as Palm Desert, is opening a new office in ... Brainsway deep transcranial magnetic stimulation (dTMS) in Southern California, successfully treating individuals struggling ...
(Date:1/17/2017)... New York (PRWEB) , ... January 17, 2017 ... ... network – SightMD – will lecture to primary eye care practitioners on the ... conditions at the upcoming 13th Semi-Annual Continuing Education Symposium, according to eye surgeon, ...
Breaking Medicine News(10 mins):
(Date:1/18/2017)...   Seno Medical Instruments, Inc. , the leader ... the development of an opto-acoustic (OA/US) imaging device, today ... SVP of Engineering. Mr. Miller previously served as the ... headquarters in Bothell, Washington . Mr. ... to the development of innovative medical imaging products that ...
(Date:1/18/2017)... 2017  Tarix Orphan LLC today announced that the ... Pediatric Disease (RPD) designation for the company,s drug candidate ... (RDEB), a rare genetic skin disorder. There are currently ... to supportive care. "The RPD designation for ... granted by the FDA in this indication," said ...
(Date:1/18/2017)... YORK , January 18, 2017 ... of people regarding the use of cannabis both for medical ... only are more Americans open to the use of cannabis, ... financial sectors. According to Arcview Market Research, the North American ... up 30% from the previous year. The research projects sales ...
Breaking Medicine Technology: