Navigation Links
MIT IDs binocular vision gene
Date:9/13/2007

CAMBRIDGE, Mass.In work that could lead to new treatments for sensory disorders in which people experience the strange phenomena of seeing better with one eye covered, MIT researchers report that they have identified the gene responsible for binocular vision.

Unlike horses and eagles, whose eyes on the sides of their heads provide two different scenes, humans see a single, in-depth view. Now researchers from the Picower Institute for Learning and Memory at MIT have identified the gene responsible for melding images from two eyes into one useful picture in the brain.

The work, which appeared in the Sept. 4 issue of the Public Library of Science (PloS) Biology and in the journal Cerebral Cortex, shows that a novel gene is necessary for binocular vision.

There are other instances in the brain where two different inputs have to be properly aligned and matchedsuch as auditory and visual projections to the midbrain that enable us to orient to sound, said lead author Mriganka Sur, Sherman Fairchild Professor of Neuroscience at the Picower Institute and head of the Department of Brain and Cognitive Sciences at MIT. This is the first study to pinpoint a gene with this kind of job.

Two points of view

Binocular vision allows us to perceive depth and carry out detailed visual processing. The images projected by each eye are aligned and matched up in brain regions called the visual thalamus and cortex.

The MIT researchers discovered that the genes Ten_m3 and Bcl6 have a key role in the early development of brain pathways for vision and touch. Ten_m3 appears to be critical for the brain to make sense of the two disparate images from each eye.

In mice that had the Ten_m3 gene knocked out, projections from their two eyes were mismatched in their brains. Because each eyes projection suppresses the other, the mice were blind, even though their eyes worked normally.

Remarkably, the researchers found that when the output of one eye was blocked at a molecular level, the knockout mice could see again. With one eyes conflicting input shut down, the other eye was able to function, though only with monocular vision.

This is an amazing instance of gain of function that proves immediately that the gene is directly responsible for creating matched projections from the two eyes, Sur said.

Human disorders in which the Ten_m family of genes is affected are often accompanied by visual deficits. There are reports of human visual conditions in which simply closing one eye allows a person to see much better, Sur said. We believe that genes such as Ten_m3 are at the heart of these disorders.


'/>"/>

Contact: Elizabeth Thomson
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology
Source:Eurekalert

Related medicine news :

1. Role of fats and oils in vision care
2. Genes for Vision discovered
3. Watching television for long hours could lead to agressiveness
4. Body mass index guide needs revision
5. Putting cancer risk with a vision
6. Risk Factors for vision problems in Diabetes
7. Watching television linked to smoking
8. Vision loss could result due to MSG
9. Televisions ruling babys world!
10. Preventing Vision Loss
11. Preventing Vision Loss
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes ... a mock evacuation of the facility as part of a disaster drill on October ... Hose EMS and Shelton City Emergency Manager, as well as the Connecticut Long ...
(Date:10/13/2017)... ... ... Ellevate Network, the leading network for professional women, brought together some of ... their inaugural Summit in New York City in June. The event was livestreamed with ... 3 million. To watch the Mobilize Women video, click here . , ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... will be giving viewers the lowdown on sciatica in a new episode of ... that focuses on current events and innovation and investigates each subject in-depth with ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian history ... The Brink” is the creation of published author, William Nowers. Captain Nowers and ... WWII veteran, he spent thirty years in the Navy. Following his career as ...
(Date:10/12/2017)... ... , ... Planet Fitness, one of the largest and fastest growing franchisors and ... flagship location in Covington, LA at 401 N. U.S. Highway 190, in January of ... Depot in the Holiday Square shopping center. Its location allows it to serve both ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... Sept. 27, 2017  Commended for their devotion to personalized ... Ranked as number one in the South Florida Business Journal,s ... Inc. 5000 yearly list, the national specialty pharmacy has found ... Bardisa will soon be honored by SFBJ as the ... Set to receive his award in October, Bardisa ...
(Date:9/25/2017)...   Montrium , an industry leader in ... IQPC Trial Master Files & Inspection Readiness Conference ... Clinical Services has selected eTMF Connect ... EastHORN, a leading European contract research organization (CRO), ... to enable greater collaboration with sponsors, improve compliance ...
(Date:9/23/2017)... Janssen Biotech, Inc. (Janssen) announced today that ... U.S. Food and Drug Administration (FDA) for the Biologics ... treatment of moderately to severely active rheumatoid arthritis (RA). ... needed to further evaluate the safety of sirukumab in ... "We are disappointed ...
Breaking Medicine Technology: