Navigation Links
MIT: Muscle 'synergies' may be key to stroke treatment
Date:10/20/2009

What's new: Researchers at MIT and San Camillo Hospital in Venice, Italy, have shown that motor impairments in stroke patients can be understood as impairments in specific combinations of muscle activity, known as synergies.

Why it matters: Previous work in animals and humans has shown that groups of muscles tend to be co-activated as a unit in predicable patterns, or synergies, across a wide range of movements. These synergies are thought to represent the fundamental building blocks from which the brain constructs complex movements. The new findings support this concept and also suggest new approaches to the rehabilitation of stroke patients. Stroke is a leading cause of long-term disability in the United States, with about 700,000 new or recurrent cases each year.

How they did it: The researchers, led by Emilio Bizzi, an MIT Institute Professor and a member of the McGovern Institute for Brain Research and the Department of Brain and Cognitive Sciences, used electromyographic (EMG) recording to measure activity in arm and shoulder muscles of eight stroke patients as they performed a variety of reaching movements. The patients had stroke damage in one cortical hemisphere only, so one arm was impaired while the other was largely unaffected. The researchers used computational methods to identify groups of muscles whose activation was correlated across movements. In seven out of eight patients, these correlations, or synergies, were largely identical between the affected and unaffected arms, even though the actual movements were very different between the two arms. The results support the view that the synergies are encoded in the brainstem or spinal cord, areas that were unaffected in these patients. "We show that descending neural signals from the motor cortex select, activate and combine a small number of muscle synergies specified by networks in the spinal cord or brainstem," Bizzi explains, "and different movements emerge as these synergies are recruited to various degrees."

Next steps: The findings suggest a new approach to the rehabilitation of stroke patients. By identifying synergies whose activations are affected following a stroke, it may be possible to develop focused rehabilitation methods that specifically train the impaired synergies. As a first step toward this goal, the researchers plan to monitor a group of stroke patients as they undergo rehabilitation therapy, to determine whether the post-stroke improvements in motor function can be explained as changes in the activation pattern of specific synergies.


'/>"/>

Contact: Jen Hirsch
jfhirsch@mit.edu
617-253-1682
Massachusetts Institute of Technology
Source:Eurekalert

Related medicine news :

1. Insulin boost restores muscle growth in elderly
2. New research provides new insight into age-related muscle decline
3. To regenerate muscle, cellular garbage men must become builders
4. Max Muscle Franchising Is Fueled By The Passion Behind The Brand
5. Muscle: Hard to build, easy to lose as you age
6. Women with strong thigh muscles protected from symptomatic knee osteoarthritis
7. For Healthy Aging, Maintaining Muscle is a Must
8. Muscle Density Linked to Disability
9. Bally Total Fitness Flexes Fundraising Muscle to Fight ALS
10. Gene Mutation Is Linked to Heart Muscle Disease
11. Max Muscle Sports Nutrition Answers Call For Safe Science-Based Weight Loss
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/21/2017)... , ... January 21, 2017 , ... Seamild, the largest ... the futuristic vision of its owner and founder. As Oat is recognized globally as ... everybody he knows personally as he believes it is a move to sow the ...
(Date:1/21/2017)... (PRWEB) , ... January 21, 2017 , ... ... of Alumni Relations, Dianne Travis-Teague, the electrifying line-up of events for its annual ... alumni, family, friends, and community. “Coming Home 2017” will be held on ...
(Date:1/21/2017)... ... January 21, 2017 , ... Santa Rosa Orthopaedics (SRO) ... located at 167 Lynch Creek Way. The Petaluma office features three comfortable patient ... and rehabilitation services and on-site x-ray services. Two multi-specialist orthopaedic surgeons Dr. ...
(Date:1/21/2017)... ... 2017 , ... The Nobel Biocare™ dental implant company is ... its creos™ line of bone regenerative products. Specifically, the Nobel Biocare™ ... creos™ allo.gain™ bone graft for a variety of bone reconstruction procedures. In addition ...
(Date:1/20/2017)... ... January 20, 2017 , ... A new partnership between ... they no longer use or need, from clothes to couches to dressers and bicycles. ... and take them to the nearest Goodwill donation center through February 28th. , ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... Research and Markets has announced the addition of ... BUN Creatinine, Electrolyte Testing, HbA1c Testing, Comprehensive Metabolic Panel, Liver Panel, ... 2024" report to their offering. ... The global clinical laboratory testing market is ... of innovative solutions on the grounds of maximum efficiency and minimum ...
(Date:1/20/2017)... BUFFALO, N.Y. , Jan. 20, 2017 /PRNewswire/ ... health programs, has announced the launch of an ... to new guidelines on opioids and helps stem ... Opioids are often prescribed to treat chronic non-cancer ... disease) despite serious risks and lack of evidence ...
(Date:1/19/2017)... NEW YORK , Jan. 19, 2017 /PRNewswire/ ... reach USD 233.7 billion by 2025, according to ... The market is anticipated to be predominantly driven ... companies, resulting into the large-scale production of new ... widen the influx of drugs at an unprecedented ...
Breaking Medicine Technology: