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MIND Institute researchers receive $1 million grant to study cognitive training in fragile X
Date:2/13/2013

onnection to ensure that the intervention is being delivered appropriately.

The program monitors training time and how participants are progressing. In addition, at the beginning and after training, the participants' parents and their school teachers will be asked to rate their behavior related to executive function to see if any improvements generalize to the person's daily life and school setting. Cogmed is providing access to the program for the research at no cost.

Hessl said that many current fragile X investigations are focused around developing targeted treatments or medications - to improve patients' cognition and behavior.

"There is a very heavy emphasis on pharmacological treatment of patients with fragile X that has initially been developed using animal models -- so most of the clinical studies going on now are on developing effective new medications that could improve synaptic connections in the brain," Hessl said. "If this study is successful a next step would be to see whether Cogmed works even better in children who are taking these medications. It might also open the door for studying this type of training in children with other types of intellectual disabilities."

The research adds to the growing capabilities of the Fragile X Research and Treatment Center, one of the world's leading fragile X clinical/research facilities, offering clinical evaluation of patients throughout the lifespan and an interdisciplinary faculty conducting clinical and basic science research to develop treatments and cures for fragile X-related conditions.

"Through this program, the fund is expanding its longstanding commitment to improving the lives of people with developmental disabilities and their families," said Olivia Farr, chair of The John Merck Fund. "The program will make approximately 10 grant awards of $1 million each."

"What's especially exciting about this program," said Marsha Mailick, chair of the fund's S
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Contact: Phyllis Brown
phyllis.brown@ucdmc.ucdavis.edu
916-734-9023
University of California - Davis Health System
Source:Eurekalert

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