Navigation Links
MIGENIX Reports Preliminary Celgosivir Viral Kinetics Study
Date:12/3/2007

VANCOUVER, and SAN DIEGO, Dec. 3 /PRNewswire-FirstCall/ - MIGENIX Inc. (TSX: MGI, OTC: MGIFF), a clinical-stage developer of drugs for infectious diseases, has received preliminary four-week interim results from a Phase II viral kinetics study in hepatitis C virus ("HCV") treatment-naive patients which indicate that celgosivir (an oral alpha glucosidase I inhibitor) has no negative effects on the tolerability, pharmacokinetics and viral kinetics when combined with the standard of care drugs, pegylated interferon plus ribavirin, as compared to the standard of care drugs alone.

The interim results include 10 patients who had completed 4-weeks of treatment equally divided between: (i) pegylated interferon (alfa-2b) plus ribavirin ("PR"); and (ii) celgosivir 400mg QD plus PR ("PRC"). The results are interim as the study is designed as a 20-patient, 12-week study. The following is a summary of the preliminary interim four-week results:

- viral kinetics in both treatment groups are similar with a median

reduction in HCV RNA at 4 weeks of 3.5 log(10) vs 3.8 log(10) in the

PRC and PR groups, respectively. The variability of response is wide

with reductions of 5.4 log(10) to 0.8 log(10) and 4.5 log(10) to

2.5 log(10) for the PRC and PR groups, respectively. Virus was

undetectable in one patient who was in the PRC group (none in the PR

group).

- PRC treatment was well tolerated, with both the PRC and PR groups

demonstrating similar tolerability, which is consistent with

observations from prior studies. Gastrointestinal tolerability of the

PRC treatment was slightly better in this study compared to prior

studies. No serious adverse events were reported.

Due to the small number of patients and the high response rate with standard of care alone, any conclusion about differences in efficacy between the groups is speculative at this point.
'/>"/>

SOURCE MIGENIX Inc.
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5 6

Related medicine news :

1. New Study Reports High Injury Rates for Hotel Workers, Even Higher Rates for Women and Nonwhites
2. Haemacure Reports Third Quarter 2007 Results
3. First-Ever List of the 5,000 Fastest-Growing Businesses Reports Total Revenue of $194.5 Billion
4. Consumer Reports Analysis: Drugs for Nerve Pain, Fibromyalgia Effective, But Not Always Best
5. MDS Reports Third Quarter 2007 Results
6. Allied Healthcare Reports Strong Fourth Quarter, Flat Net Income for Fiscal 2007 vs. 2006
7. AtriCure Reports First Human Implant of the Cosgrove-Gillinov Left Atrial Appendage Occlusion System
8. NMHC Reports Fourth Quarter and Fiscal Year 2007 Financial Results
9. Blue Cross and Blue Shield of Florida Reports Eighteenth Consecutive Year of Positive Performance
10. ReBuilder Medical Technologies, Inc. Reports International Sales Expansion
11. AdCare Health Systems, Inc. Reports Discontinuation of Definitive Merger Agreement with Family Home Health Services, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... about to be tested in a clinical trial by ... for Alzheimer,s disease has failed to work with the ... according to results of a study by University of ... neuroscience affiliated with the Evelyn F. and William L. ... the importance of verifying promising research results before investing ...
(Date:5/23/2013)... negative" carries a poor prognosis, with limited treatment options. ... cells the way it,s supposed to. New research from ... to chemotherapy, and identifies a mechanism to rectify that. ... PhD, and his team at Western,s Schulich School of ... functions to promote the death of cancer cells by ...
(Date:5/23/2013)... New York (PRWEB) May 23, 2013 ... by C.R. Bard, Inc., continue to move forward in ... Southern District of West Virginia, Bernstein Liebhard LLP reports. ... Court denied a request by C.R. Bard to seal ... reveal trade secrets and other confidential, proprietary information about ...
(Date:5/23/2013)... Former United States Vice President Dick ... 's annual Paramedic Luncheon. , In front of ... praised Acadian's medics, saying, "I am delighted to be ... the Paramedic of the Year Award. I think it's ... of competition within a company like this because there ...
(Date:5/23/2013)... Jackson, TN (PRWEB) May 23, 2013 Spring ... fit, but what’s gotten into Jackson , the city ... variety of new fitness facilities and wellness centers has transformed ... in the state. , “In any city of vibrant, ... to improve or promote health,” said Kim White, owner of ...
Breaking Medicine News(10 mins):Health News:Anti-cancer drug viewed as possible Alzheimer's treatment doesn't work in UF study 2Health News:Anti-cancer drug viewed as possible Alzheimer's treatment doesn't work in UF study 3Health News:Transvaginal Mesh Lawsuits Move Forward, as Bernstein Liebhard LLP Notes New Order in Federal C.R. Bard Mesh Implant Lawsuits 2Health News:Transvaginal Mesh Lawsuits Move Forward, as Bernstein Liebhard LLP Notes New Order in Federal C.R. Bard Mesh Implant Lawsuits 3Health News:Acadian Ambulance Honors Paramedic of the Year at Annual Luncheon 2Health News:Grass Roots Wellness Initiative Builds Muscle in Jackson, Tennessee 2Health News:Grass Roots Wellness Initiative Builds Muscle in Jackson, Tennessee 3Health News:Grass Roots Wellness Initiative Builds Muscle in Jackson, Tennessee 4
... other conditions related to chronic kidney disease are independently ... heart disease is associated with a decline in kidney ... two reports in the issue of Archives of Internal ... prevalent in the United States and worldwide, according to ...
... of doctors using advertisements to lure patients to their ... state's medical council to take steps to ban such ... minister Tikshan Sood said here that advertisements given by ... violation of the Medical Council Act. ,"The ...
... will give lifelong benefit to patients and it is also ... . ,Compared to traditional jabs, the new FLU-v vaccine ... a global epidemic. "We expect one course of injections - ... immunity," the Daily Mail quoted Dr Stuart Robinson of the ...
... Kingdom have found that patients with COPD, or chronic ... researchers also found that those COPD patients with osteoporosis, ... greater arterial stiffness. These premature signs of aging may ... cardiovascular disease. ,Their research results appear in ...
... researchers have identified common DNA variations that underlie ... the eight genetic alterations the scientists identified ... A few, however, reduced fever risk. ... genetic variations linked to fever following smallpox vaccination ...
... The research by a team of Emory University scientists ... altered by genetic mutations recently identified in Parkinson disease development. ... function and could provide a target for drug therapies to ... disorder of the central nervous system resulting from the loss ...
Cached Medicine News:Health News:Studies Identify Interactions Between Heart Disease, Kidney Disease 2Health News:Premature Vascular and Bone Changes Occur in COPD Patients 2Health News:Premature Vascular and Bone Changes Occur in COPD Patients 3Health News:Genetic Variations Leads to Fever After Smallpox Vaccination 2Health News:Genetic Variations Leads to Fever After Smallpox Vaccination 3Health News:Parkinsons Disease Protein Pathway Identified 2
(Date:5/23/2013)... , May 23, 2013  Texas, premier physician ... deliver doctors the survival tools they need to provide ... in today,s health care marketplace. "I am ... save local practices," said Stephen L. Brotherton ... (TMA). " Texas doctors are determined ...
(Date:5/23/2013)...  Ameritox, the nation,s leader in pain medication ... to become part of its Urine Drug Monitoring ... and improve the clinical outcomes for injured workers. ... manager in the workers, compensation industry, has used ... management strategy for several years. By establishing a ...
(Date:5/23/2013)... Medical Systems, Inc. (NASDAQ: CASM ) (CASMED), a ... that Thomas M. Patton , President and ... Annual Marcum MicroCap Conference on Thursday, May 30, 2013, at ... . The presentation is scheduled to begin ... will be available via a live webcast at http://wsw.com/webcast/marcum/casm/ ...
Breaking Medicine Technology:TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4Ameritox Joins with Progressive Medical in Urine Drug Monitoring Network to Help Improve Care of Injured Workers 2Ameritox Joins with Progressive Medical in Urine Drug Monitoring Network to Help Improve Care of Injured Workers 3CASMED to Present at the 2nd Annual Marcum MicroCap Conference 2
... Texas, Oct. 14 Lexicon Pharmaceuticals, Inc. (Nasdaq: ... public offering of shares of its common stock. ... Lexicon,s common stock after the exercise in full by ... L.P., Lexicon,s largest stockholder, of its associated right to ...
... ST. PETERSBURG, Fla., Oct. 14 In the United States, ... according to the American Cancer Society. Except for skin ... woman. , To help fight this ... will donate $10 for every pink Personal Health Records (PHR) ...
Cached Medicine Technology:Lexicon Announces Completion of Public Offering of Common Stock 2Lexicon Announces Completion of Public Offering of Common Stock 3Breast Cancer Survivors and Patients Encouraged to Have Medical History Readily Available 2Breast Cancer Survivors and Patients Encouraged to Have Medical History Readily Available 3
5 mm diameter blade. Angled 45 degrees. Hexagonal handle....
0.5 mm wide x 1.5 mm long. Angled 20 degrees. Octagonal handle....
8 mm downcutting Royce blade. Angled shaft. 60 mm from angle to tip....
3 mm disposable bevel blades. Malleable shafts. Blades packaged 6 per package....
Medicine Products: