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MGH Neurological Clinical Research Institute and Prize4Life receive Bio-IT World award
Date:4/12/2013

The Massachusetts General Hospital (MGH) Neurological Clinical Research Institute (NCRI) and Prize4Life, a nonprofit organization whose mission is to accelerate the discovery of treatments and a cure for amyotrophic lateral sclerosis (ALS), received a Best Practices Award at the 2013 Bio-IT World Conference & Expo. Presented on April 10, the award acknowledged the creation of the Pooled Resource Open-access ALS Clinical Trials (PRO-ACT) platform.

The PRO-ACT platform was chosen from 33 detailed submissions for the Bio IT World award and was honored in the "Clinical & Health IT" category. The dynamic database helps to accelerate discovery, development and delivery of future ALS treatments by housing the largest dataset from completed Phase II and III clinical trials in ALS. The platform enables the merging of data from global clinical trials, generating a valuable resource for the design of future trials and the identification of novel correlations and disease biomarkers.

The PRO-ACT database, contains more than 8,500 fully deidentified, unique clinical patient records both treatment and placebo data from 17 late-stage industry and academic trials and over 8 million data points, including 1.7 million records of lab test results of ALS patients. "The results garnered through the use of the PRO-ACT platform will benefit more than just the scientific and medical research fields; they will also impact ALS patients and their families, potentially by giving them answers to their currently unanswerable questions," states Alexander Sherman, NCRI director of Systems and a pioneering force behind the launch. "It is an unprecedented opportunity to increase the field's understanding of the ALS patient population and the natural history of the disease."

Melanie Leitner, PhD, Prize4Life chief scientific officer says, "We have been thrilled at the ALS community's enthusiastic response to PRO-ACT since its December 2012 launch, including 1
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Contact: Devon Punch
dpunch@partners.org
617-724-7210
Massachusetts General Hospital
Source:Eurekalert

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