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MDS Nordion Submits Expression of Interest Proposal to Government of Canada on Medical Isotope and Generator Production
Date:7/30/2009

used by the world's leading isotope producing reactors. The computer codes are specifically designed to model research reactor performance and operation and are being used by the High Flux Reactor in Petten, Netherlands, and SAFARI-1, in South Africa. Adopting the OSCAR computer codes could be essential to resolving the existing discrepancy between the predicted and measured value of the power coefficient of reactivity of the MAPLE reactors allowing them to be licensed by the Canadian Nuclear Safety Commission (CNSC) for safe operation.

During the Standing Committee on Natural Resources session on June 4, 2009, Mr. Peter Elder, Director General, Directorate of Nuclear Cycle and Facilities Regulation, Canadian Nuclear Safety Commission, stated "The issue is not whether, necessarily, there's any problem with a positive coefficient. It was a mismatch between the (value) predicted in their safety case in the computer codes that said it should be negative and the actual measurements in the reactor that turned out to be positive, which means there was something in those computer codes that was not modeling what was happening in the reactor."

As a key collaborator in the project, "Necsa is honoured to be considered part of this important endeavour needed to secure a stable and reliable supply of Mo-99 and Tc-99m to the market by offering its comprehensive expertise in the physics and operation of material test reactors and the OSCAR system to support MDS Nordion's project proposal" stated Rob Adam, Necsa CEO in his response to the invitation by MDS Nordion to join the MAPLE project.

In addition to the OSCAR computer codes, MDS Nordion is proposing the construction of a fully licensed production facility to manufacture Tc-99m generators for distribution to Canadian hospitals in all regions of Canada and abroad. With previous experience in this area, MDS Nordion will build, operate and maintain the generator production line, and perform all necessary
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5. MDS Nordion Launches Improved TheraSphere(R) Administration System for Physicians
6. MDS Nordion Provides Update on AECLs Medical Isotope Supply Disruption
7. MDS Nordion Opens New Radiopharmaceutical Production Facility in Belgium
8. MDS Nordion Urges Government of Canada to Complete MAPLE Project to Address Current Medical Isotope Supply Shortage
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10. MDS Nordion Continues to Urge Government of Canada to Complete MAPLE Project to Address Critical Medical Isotope Shortage
11. Cephalon Submits New Drug Application for TREANDA for the Treatment of Chronic Lymphocytic Leukemia
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