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MDS Announces Substantial Issuer Bid
Date:2/19/2010

bligations retained and projected adjustments with respect to such sales and their success as ongoing businesses, the Company's ability to retain customers as a result of any perceived uncertainty related to the planned sales of our MDS Pharma Services Early Stage operations, the fact that our operations will be substantially reduced as a result of the sale of MDS Analytical Technologies and MDS Pharma Services Early Stage operations, successful implementation of structural changes, including restructuring plans, technical or manufacturing or distribution issues, the competitive environment for MDS's products and services, the degree of market penetration of MDS's products and services, the ability to secure a reliable supply of raw materials, the impact of MDS's clients exercising rights to delay or cancel certain contracts, the strength of the global economy, the stability of global equity markets, the availability and cost of financing, the impact of the movement of the U.S. dollar relative to other currencies, particularly the Canadian dollar and the euro, uncertainties associated with critical accounting assumptions and estimates, satisfaction of the conditions in the offer, and other factors set forth in reports and other documents filed by MDS with Canadian and U.S. securities regulatory authorities from time to time, including MDS's quarterly and annual MD&A, Annual Information Form, and Annual Report on Form 40-F for the fiscal year ended October 31, 2009 filed with the SEC.

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