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MDS Analytical Technologies Releases MetaXpressPowerCore(TM) and MetaXpress(R) 3.0 Cellular Imaging Software

Enhancements Increase Flexibility and High-Content Screening Throughput

SUNNYVALE, CA, April 27 /PRNewswire-FirstCall/ - MDS Analytical Technologies, a leader in innovative solutions for drug discovery and life sciences research, today announced at the Society for Biomolecular Sciences (SBS) Conference and Exhibition 2009 in Lille, France, the availability of the MetaXpressPowerCore(TM) and MetaXpress(R) 3.0 image acquisition and analysis software. These advancements are designed to accelerate the throughput of High-Content Screening (HCS) and expand toxicity applications to include micronuclei detection.

MetaXpressPowerCore(TM) software improves workflow and significantly reduces overall time required for HCS screens by dramatically increasing image analysis speeds. Image analysis is improved by leveraging a novel parallel-processing infrastructure that can be scaled to the user's throughput need. MetaXpressPowerCore(TM) software integrates with the existing MetaXpress(R) platform and MDCStore(TM) data-management solution, and is licensed by the number of processes required. MetaXpressPowerCore(TM) is compatible with the entire suite of MetaXpress(R) application modules.

MetaXpress(R) 3.0 software introduces a number of ease-of-use improvements, including new data- management utilities, such as database optimization, data archival and deletion. MetaXpress(R) 3.0 analysis is compatible with Microsoft's Windows Vista operating system, and runs all of the most recent features of MetaMorph(R) 7.6 software.

"Cellular imaging technology has become integral to drug discovery, research and screening, and improvements in flexibility and speed are critical for customers," said Andy Boorn, President of MDS Analytical Technologies. "The next milestone for HCS is scaling up to primary screening with imaging technology. Elimination of image analysis bottlenecks with these new products is a major accomplishment toward realizing this goal."

Another enhancement to MetaXpress(R) 3.0 software is the release of the Micronuclei Application Module that allows users to find, evaluate and quantitate micronuclei in nucleated cells for HCS. This product uses a proprietary algorithm that is a significant improvement over existing competitive micronuclei detection methods. Using additional probes, this new application module makes it possible for users to additionally differentiate between mitotic, apoptotic, and necrotic cells, expanding the toxicology measurement suite significantly.

MDS Analytical Technologies at SBS Conference and Exhibition 2009

MetaXpressPowerCore(TM) and MetaXpress(R) 3.0 software programs are being presented to attendees at the Society for Biomolecular Sciences Conference and Exhibition 2009, which is being held April 26-30, in Lille, France. MDS Analytical Technologies can be found at booth 76.

About MetaXpress(R) Software

The MetaXpress(R) program is based on the MetaMorph(R) software backbone, and is used to power the suite of cellular imaging instruments and analysis software for automated imaging and HCS. MetaXpress(R) software is integrated with a data-management solution, turnkey application modules, and the PowerCore analysis option that increases the flexibility and overall speed of workflow.

About MDS Analytical Technologies

MDS Analytical Technologies, a business unit of MDS Inc., is focused on the research, design, manufacture and marketing of state-of-the-art tools for mass-spectrometry, drug discovery and bioresearch. MDS Analytical Technologies' products are designed to help accelerate the complex process of discovering and developing new drug compounds, and are sold to research scientists around the world. The mass-spectrometer product lines are also sold globally through joint ventures with two of the world's leading analytical instrumentation and life-sciences companies, Life Technologies Corporation and PerkinElmer, Inc. Find out more at or

About MDS Inc.

MDS Inc. (TSX: MDS; NYSE: MDZ) is a global life-sciences company that provides market-leading products and services that our customers need for the development of drugs and diagnosis and treatment of disease. We are a leading global provider of pharmaceutical contract research, medical isotopes for molecular imaging, radiotherapeutics, and analytical instruments. MDS, Inc. has more than 5,000 highly skilled people in 29 countries. Find out more at or by calling 1-888-MDS-7222, 24 hours a day.

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