Navigation Links
MAP Pharmaceuticals Phase 3 Trial of LEVADEX(TM) Migraine Product Candidate Meets All Four Primary Endpoints
Date:5/26/2009

- Both Rapid and Sustained Pain Relief for up to 48 Hours -

- Conference Call to be Held Today at 8:30 a.m. ET -

MOUNTAIN VIEW, Calif., May 26 /PRNewswire-FirstCall/ -- MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) announced today that the efficacy portion of its first Phase 3 clinical trial evaluating its novel LEVADEX(TM) orally inhaled migraine therapy met all four primary endpoints. Additional endpoints showed that LEVADEX provided rapid and sustained pain relief for up to 48 hours after dosing.

Patients taking LEVADEX therapy (formerly referred to as MAP0004) had statistically significant improvement at two hours compared to patients on placebo for each of the primary endpoints:

  • Pain relief: 58.7 percent of patients who received LEVADEX compared with 34.5 percent for placebo (p<0.0001);
  • Phonophobia free: 52.9 percent of patients who received LEVADEX compared with 33.8 percent for placebo (p<0.0001);
  • Photophobia free: 46.6 percent of patients who received LEVADEX compared with 27.2 percent for placebo (p<0.0001); and
  • Nausea free: 67.1 percent of patients who received LEVADEX compared with 58.7 percent for placebo (p=0.02).

A total of 792 patients were included in the primary data analysis as specified in the protocol of the FREEDOM-301 study, which was conducted under a Special Protocol Assessment agreement with the U.S. Food and Drug Administration (FDA). The patient population studied had more severe migraine pain than expected, with 46 percent reporting severe pain and 54 percent reporting moderate pain prior to administration of the study drug.

Results from additional pre-defined analyses include:

  • LEVA
    '/>"/>

SOURCE MAP Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Agios Pharmaceuticals founders author Science review on cancer metabolism
2. Transcept Pharmaceuticals Presents Data from Studies of Two Product Candidates at Annual Meeting of the American Psychiatric Association
3. Celator(R) Pharmaceuticals Initiates Research Agreement With Cephalon, Inc.
4. Sagent Pharmaceuticals Announces Extension of Series A Financing
5. NSD Bio Group, LLC Selected By U.S. - China Economic & Security Review Commission for Analysis of Chinas Pharma Supply Chain on U.S. Pharmaceuticals
6. Aragon Pharmaceuticals Announces $8 Million Series A Financing
7. Webcast Alert: Isis Pharmaceuticals To Provide General Corporate Update in Conjunction with 2009 Annual Meeting of Stockholders
8. Trubion Pharmaceuticals, Inc. to Present Positive Data From a Phase 2b Re-treatment Study of TRU-015 at the 2009 EULAR Annual Meeting
9. Lotus Pharmaceuticals, Inc. Reports First Quarter 2009 Financial Results
10. Jiangbo Pharmaceuticals Reports Results for the Third Quarter of its Fiscal Year 2009
11. InDex Pharmaceuticals AB Engages PharmaVentures to Facilitate the Licensing of Kappaproct(R) After Phase IIa Trial Achieves Clinical Endpoints Early
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2015)... 27, 2015 The 2015 Deep ... a professional and in-depth study on the current ... with a focus on the Chinese situation. , ... industry including definitions, classifications, applications and industry chain ... both the international and Chinese domestic situations including ...
(Date:3/27/2015)... March 27, 2015 Smile Brands Inc. ... of business support services to dental groups in the ... affiliated Castle Dental office in Hendersonville, TN. ... TN 37075, this new Castle Dental office provides families ... the latest in comprehensive, quality dental care. Hendersonville marks ...
(Date:3/27/2015)... Washington, DC (PRWEB) March 27, 2015 ... partnership with Accelerate Brain Cancer Cure (ABC2), awarded $350,000 ... institutions: University of Florida, The Scripps Research Institute and ... The awards support studies with a clear development path ... for patients in the near future. , The ...
(Date:3/26/2015)... (PRWEB) March 26, 2015 Elfster.com, the ... addition of its bucket list generator capabilities to its ... course, refers to a list that one creates of ... the 2007 movie of the same name. Nowadays ... way to memorialize their summer achievements. , "We are ...
(Date:3/26/2015)... North American Seminars launches it new ... to providing information regarding OT PT continuing education courses ... As a leader in live hands PT continuing ... live and online continuing education courses. , ... A Master Clinicians Approach to Advanced Concepts in Examination ...
Breaking Medicine News(10 mins):Health News:Glutathione Industry International and China Market Analysis Report 2015-2020 2Health News:Glutathione Industry International and China Market Analysis Report 2015-2020 3Health News:Castle Dental® Opens Its First Dental Office in Hendersonville, TN 2Health News:Castle Dental® Opens Its First Dental Office in Hendersonville, TN 3Health News:The Florida Center for Brain Tumor Research and Accelerate Brain Cancer Cure Award $350,000 to Florida-Based Researchers 2Health News:The Florida Center for Brain Tumor Research and Accelerate Brain Cancer Cure Award $350,000 to Florida-Based Researchers 3Health News:Plans for Bucket List Generator - Just In Time for Summer - Announced by Elfster 2Health News:North American Seminars Launches Healthclick.com, a New Mobile Ready Website, Providing CME Course Information to PT, PTA, OT and ATC's 2Health News:North American Seminars Launches Healthclick.com, a New Mobile Ready Website, Providing CME Course Information to PT, PTA, OT and ATC's 3
... By Amanda Gardner HealthDay Reporter , TUESDAY, April ... take calcium supplements to prevent bone deterioration may, in fact, be ... previous studies with similar findings, the new conclusions don,t necessarily mark ... study released online April 19 in the BMJ . ...
... at the University of Pennsylvania School of Medicine are delving ... of chromosomes. Recent work, e-published in Nature Structural & ... telomeres, can be protected by caps made up of specialized ... Telomere caps are like a knot at the end of ...
... major discovery about an enzyme,s structure has opened a window ... have determined the structure of a nuclease that will help ... for cancer research. DNA repair pathways are very important ... tools the cell uses to do those repairs are not ...
... that will test whether heart disease drugs can be used ... class of drugs - known as statins - can prevent ... cent of pregnant women in the UK. The ... research showing that statins, which are prescribed to lower heart ...
... HealthDay Reporter , TUESDAY, April 19 (HealthDay News) -- ... to curb misuse of extended-release and long-acting opioid pain killers ... Risk Evaluation and Mitigation Strategy (REMS) is part of a ... reduce overall prescription drug abuse in the United States. ...
... The European College of Neuropsychopharmacology (ECNP) is pleased ... the 2011 ECNP Neuropsychopharmacology Award in Basic Science ... the brain adenosine system. The ECNP Neuropsychopharmacology Award ... neuropsychopharmacology and closely related disciplines. The award is ...
Cached Medicine News:Health News:Women Taking Calcium Supplements May Risk Heart Health, Researchers Say 2Health News:Women Taking Calcium Supplements May Risk Heart Health, Researchers Say 3Health News:Ends of chromosomes protected by stacked, coiled DNA caps 2Health News:Ends of chromosomes protected by stacked, coiled DNA caps 3Health News:Nature's elegant solution to repairing DNA in cancer, other conditions 2Health News:Heart drugs could cut blood pressure risks in pregnancy 2Health News:FDA Looks to Crack Down on Misuse of Opioid Painkillers 2Health News:Bertil Fredholm wins the 2011 ECNP Neuropsychopharmacology Award in basic science research 2
(Date:3/27/2015)... 27, 2015 Concord Medical Services Holdings ... CCM ), a leading specialty hospital management solution ... radiotherapy and diagnostic imaging centers in ... a purchase agreement under which Concord Medical Services ... the Company, agreed to acquire the Fortis Surgical ...
(Date:3/26/2015)... HOUSTON , March 26, 2015  The ... of a study independently conducted by the Department ... Japan have been published. ... compared 5-fluorouracil hepatic arterial infusion as post-operative adjuvant ... colorectal metastasis of the liver. ...
(Date:3/26/2015)... , March 26, 2015 Huntington Memorial Hospital ... to perform transcatheter aortic valve replacement (TAVR), a minimally ... a revolutionary new way to replace an aortic valve ... heart lung machine. The procedure is performed ... by Azhil ( Alex) Durairaj , MD, interventional cardiologist ...
Breaking Medicine Technology:Concord Medical Announces Acquisition of Fortis Surgical Hospital in Singapore 2Concord Medical Announces Acquisition of Fortis Surgical Hospital in Singapore 3Huntington Memorial Hospital Performs Groundbreaking Minimally Invasive Replacement of Heart Valves 2
... WASHINGTON, Oct. 19 Mylan Pharmaceuticals, UDL Laboratories, AstraZeneca ... agreements for a total of $124 million to resolve ... failing to pay appropriate rebates to state Medicaid programs ... Department announced today. , The Medicaid Prescription Drug ...
... , INDIANAPOLIS, Oct. 19 The board of directors of Eli ... for the fourth quarter of 2009 of $0.49 a share on ... paid in the first three quarters of 2009 and brings the ... http://www.newscom.com/cgi-bin/prnh/20031219/LLYLOGO ) , The dividend is ...
Cached Medicine Technology:Four Pharmaceutical Companies Pay $124 Million for Submission of False Claims to Medicaid 2Four Pharmaceutical Companies Pay $124 Million for Submission of False Claims to Medicaid 3
... 1200 system features a small footprint, which allows it ... , Standardization as Part of the ADVIA Chemistry Family ... calibrators and controls as the other members of the ... proven reliability. , , Meets Workload Needs ...
... ZIP Anchor is a family of titanium ... and suture options. The ZIP anchor is ... size with either one strand or two ... Needles are attached to each suture strand ...
... a unique double loaded anchor perfect for rotator ... Lactic Acid (PLLA) and comes in two sizes: ... suture ends for open repairs, and can easily ... inserter allows insertion with minimal procedural steps and ...
RCB™ Rotator Cuff Buttress is a completely resorbable plate that will alleviate suture migration in open or mini-Open rotator cuff repairs....
Medicine Products: