Navigation Links
MAP Pharmaceuticals Phase 3 Trial of LEVADEX(TM) Migraine Product Candidate Meets All Four Primary Endpoints
Date:5/26/2009

- Both Rapid and Sustained Pain Relief for up to 48 Hours -

- Conference Call to be Held Today at 8:30 a.m. ET -

MOUNTAIN VIEW, Calif., May 26 /PRNewswire-FirstCall/ -- MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) announced today that the efficacy portion of its first Phase 3 clinical trial evaluating its novel LEVADEX(TM) orally inhaled migraine therapy met all four primary endpoints. Additional endpoints showed that LEVADEX provided rapid and sustained pain relief for up to 48 hours after dosing.

Patients taking LEVADEX therapy (formerly referred to as MAP0004) had statistically significant improvement at two hours compared to patients on placebo for each of the primary endpoints:

  • Pain relief: 58.7 percent of patients who received LEVADEX compared with 34.5 percent for placebo (p<0.0001);
  • Phonophobia free: 52.9 percent of patients who received LEVADEX compared with 33.8 percent for placebo (p<0.0001);
  • Photophobia free: 46.6 percent of patients who received LEVADEX compared with 27.2 percent for placebo (p<0.0001); and
  • Nausea free: 67.1 percent of patients who received LEVADEX compared with 58.7 percent for placebo (p=0.02).

A total of 792 patients were included in the primary data analysis as specified in the protocol of the FREEDOM-301 study, which was conducted under a Special Protocol Assessment agreement with the U.S. Food and Drug Administration (FDA). The patient population studied had more severe migraine pain than expected, with 46 percent reporting severe pain and 54 percent reporting moderate pain prior to administration of the study drug.

Results from additional pre-defined analyses include:

  • LEVA
    '/>"/>

SOURCE MAP Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Agios Pharmaceuticals founders author Science review on cancer metabolism
2. Transcept Pharmaceuticals Presents Data from Studies of Two Product Candidates at Annual Meeting of the American Psychiatric Association
3. Celator(R) Pharmaceuticals Initiates Research Agreement With Cephalon, Inc.
4. Sagent Pharmaceuticals Announces Extension of Series A Financing
5. NSD Bio Group, LLC Selected By U.S. - China Economic & Security Review Commission for Analysis of Chinas Pharma Supply Chain on U.S. Pharmaceuticals
6. Aragon Pharmaceuticals Announces $8 Million Series A Financing
7. Webcast Alert: Isis Pharmaceuticals To Provide General Corporate Update in Conjunction with 2009 Annual Meeting of Stockholders
8. Trubion Pharmaceuticals, Inc. to Present Positive Data From a Phase 2b Re-treatment Study of TRU-015 at the 2009 EULAR Annual Meeting
9. Lotus Pharmaceuticals, Inc. Reports First Quarter 2009 Financial Results
10. Jiangbo Pharmaceuticals Reports Results for the Third Quarter of its Fiscal Year 2009
11. InDex Pharmaceuticals AB Engages PharmaVentures to Facilitate the Licensing of Kappaproct(R) After Phase IIa Trial Achieves Clinical Endpoints Early
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... 2013 General Data Company Inc., ... tracking and data management products and solutions, has ... Inc., (TBS) of Durham, North Carolina, a leading ... for the clinical and research pathology marketplace. TBS ... which provides specialty products and solutions to hospitals, ...
(Date:5/24/2013)... the first conference of its kind, Impacts World ... and decision makers from politics, business and civil ... integrated climate impact research across sectors and scales. ... World 2013 on May 27th, 1pm to 1:55pm ... , Speakers include: , Connie Hedegaard, ...
(Date:5/24/2013)... Finding the answer for this is at the centre of ... the Bergen fMRI Group at the University of Bergen (UiB) ... The way they do this is by studying people who ... mental illness. For a five-year period, the group is studying ... report published in Frontiers in Human Neuroscience shows ...
(Date:5/24/2013)... May 24, 2013 The Icahn School ... International (CDI) exclusive license rights to commercially develop ... medicine applications. These cells are capable of further differentiation ... cardiomyocytes, endothelial cells, and vascular smooth muscle cells, and ... damaged heart tissue. , The original agreement announced in ...
(Date:5/24/2013)... The creative flair and design talent of ... Institute of Textiles and Clothing (ITC) have won applause ... held on 22 May at The Mira Hong Kong. ... design students, various knitwear producers and yarn suppliers, the ... four outfits from 20 graduating students majoring in knitwear ...
Breaking Medicine News(10 mins):Health News:General Data Acquires Triangle Biomedical Sciences 2Health News:General Data Acquires Triangle Biomedical Sciences 3Health News:Help at hand for schizophrenics 2Health News:Icahn School of Medicine at Mount Sinai Grants Exclusive License to Cellular Dynamics International for Development of a Cellular Therapy for Cardiac Muscles 2Health News:Icahn School of Medicine at Mount Sinai Grants Exclusive License to Cellular Dynamics International for Development of a Cellular Therapy for Cardiac Muscles 3Health News:Icahn School of Medicine at Mount Sinai Grants Exclusive License to Cellular Dynamics International for Development of a Cellular Therapy for Cardiac Muscles 4Health News:PolyU Stages Knitwear Fashion Show 2
... of their work linking mutations in BRAC2 gene leading to ... Journal of Medical Ethics. //Mutations in BRAC2 gene which was ... women has now found to increase the risk of development ... the study also confirmed the relation between BRAC2 mutations and ...
... population its possible to drive safely if they take ... latest edition of Harvard Men's Health Watch, chronic illnesses ... for auto accidents. Even normal, healthy aging can take ... sensory abilities. But simple preparations and precautions can help ...
... risk of picking up infections like MRSA if they glucose ... recent issue of the journal Thorax.// ,The authors base ... in intensive care who required mechanical help with their breathing ... medical and surgical specialties., ,Levels of glucose were measured ...
... from Johns Hopkins had found that patients, who are treated ... follow all the advice of their physicians for effective treatment ... of more than 5,000 Americans, those who said they were ... likely to report higher levels of satisfaction with their care, ...
... have discovered the brain patterns associated with amusia or tone ... associated with other learning disorders like dyslexia. // ... are tone deaf -- in scientific terms, suffering from amusia ... note from another. The disorder can be congenital, present from ...
... before. The problem seems to be worse now that scientists ... proves, when it comes to being overweight, past is most ... shows that we can't afford to wait," said Vivien Morris, ... that brought the girls to the health center's pool, a ...
Cached Medicine News:Health News:Critically Ill Patients More At Risk Of Infection If Glucose Is Present In Their Lung Secretions 2Health News:Early Awareness About Weight Management Needed To Tackle Lifelong Obesity 2
(Date:5/24/2013)... 24, 2013 The potential of ... delivery of therapeutic agents has been receiving undeniable attention ... showing significant promise. The crucial formulation considerations for orally ... play a major role in the efficiency of pulmonary ... development of new formulation techniques and devices in recent ...
(Date:5/23/2013)... y PARÍS, 24 de mayo de ... ), un destacado desarrollador y fabricante de herramientas ... la diagnosis y tratamiento de la enfermedad vascular ... del ensayo ADVISE ( Ad enosine V ... E valuation) II durante la sesión de ensayo ...
(Date:5/23/2013)... , May 23, 2013 Nephros, Inc. (OTC ... medical device company that develops and sells high performance ... its rights offering.  In addition, the concurrent temporary reduction ... expired on May 17, 2013. Nephros estimates ... from the rights offering.   A portion of the proceeds ...
Breaking Medicine Technology:Inhalaltion Drug Delivery: 11-12 September - Berlin, Germany 2Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 2Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 3Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 4Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 5Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 6Nephros Announces Completion of Rights Offering 2Nephros Announces Completion of Rights Offering 3Nephros Announces Completion of Rights Offering 4
... SILVER SPRING, Md., May 9, 2011 /PRNewswire-USNewswire/ – CoMeD ... a Republican State Senator filed an amendment to regulate ... made it illegal to buy, sell, manufacture, deliver, import, ... 0.3 micrograms of organic or inorganic mercury per milliliter ...
... May 9, 2011 TriReme Medical, Inc. (TriReme), a ... treatment of complex vascular disease, announced today the appointment ... their Board of Directors. Mr. Bose, Founder ... Singapore and was until recently Company Group Chairman at ...
Cached Medicine Technology:Florida Legislature Refuses to Limit Mercury in Vaccines 2Florida Legislature Refuses to Limit Mercury in Vaccines 3TriReme Medical Lines Up Asian Strategy With Key Appointment of New Board Members 2
The 7700 Reciprocating Saw completes the large power system with our simple twist-lock blade hub and selection of saw blades....
The 7500 Drill/Reamer operates at two speeds for multiple applications, which is automatically controlled by the 16 different coupler attachments. The drill reamer can be used for, but is not limited...
... SmartDriver System consists of a pistol-grip handpiece ... with a wide range of couplers that ... orthopedic surgical applications., ,The Battery SmartDriver ... compared to the original Battery SmartDriver. The ...
... Meniscus Implant (CMI) is a type I ... irreparable meniscus tear or loss of meniscus ... procedure. The purpose of the CMI ... and return to a more vigorous lifestyle, ...
Medicine Products: