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Lymphoma patients with cardiovascular disease have increased risk of cardiac hospitalization
Date:7/2/2010

valuative Sciences, Ontario, Canada, and senior author of the study. "However, the lower cardiac complication rate among patients treated only with chemotherapy occurred in part because they were more likely to die of other causes, so it is not a simple message that chemotherapy alone is better for all patients. Clinical trials are ongoing to more accurately identify which patients benefit from radiation therapy and to further reduce the administered dose to normal tissues," Hodgson said. "But oncologists need to be be aware of their patients' heart health and vigilant about post-treatment monitoring and active intervention to reduce their patients' cardiac risk factors."

Possible explanations for this relationship have been cited in animal studies that have shown that when an artery is exposed to radiation, inflammation appears in the arterial wall and can lead to the rupture of fatty deposits, which is a common cause of heart attacks in humans. This may, in part, explain the increased risk of heart problems following radiation therapy to the chest in patients who likely have such fatty deposits in their coronary arteries.


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Contact: Wendy Stokes
wstokes@hematology.org
202-552-4927
American Society of Hematology
Source:Eurekalert

Page: 1 2

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