Navigation Links
Lyme Rash Reappearance Probably Signals New Infection, Study Says
Date:11/15/2012

By Serena Gordon
HealthDay Reporter

WEDNESDAY, Nov. 14 (HealthDay News) -- If you've had Lyme disease in the past and you develop another bull's-eye rash -- the hallmark of Lyme disease -- you probably have a new infection rather than a relapse of your initial infection, according to a small new study.

One implication of the study might be that since people don't suffer relapses from Lyme infection, it's not necessary to treat them with long-term antibiotics as a preventive measure.

For people whose symptoms do recur, it's especially likely that it's from a new infection if the rash shows up in a different site than the initial infection. It's also especially likely to be a new infection if it occurs during the prime tick season, which is from late spring through the summer, the study authors said.

"When people take the relatively short course of antibiotics that are ... recommended by the Infectious Diseases Society of America, the infection is likely to be cured," said the study's lead author, Dr. Robert Nadelman, a professor of medicine in the division of infectious diseases at New York Medical College in Valhalla, N.Y.

"But be aware that if you live, work or do recreation in an area with ticks, you can get tick bites again, and you can get Lyme again," he added. "If you see a tick on you, remove it promptly; take precautionary steps to try to avoid getting ticks on you."

Results of the study are published in the Nov. 15 issue of the New England Journal of Medicine.

The bull's-eye rash (called erythema migrans) that is usually the first clue that someone has been infected with Lyme disease generally disappears after treatment, according to study background information. But the rash comes back in about 15 percent of people who have had Lyme. Currently available tests can't differentiate between a new infection or a recurrent one. This can lead people to believe that they have a long-standing infection that requires long-term antibiotic therapy.

Ratner and his colleagues wanted to assess just how often a new bull's-eye rash is linked to a new infection or a recurrent one. To do this, they tested 22 skin or blood samples from 17 people who'd had a Lyme infection and then had a second, third or fourth episode of a new bull's-eye rash.

The researchers ran genetic tests on the samples to see if the strains of Borrelia burgdorferi were the same or different in each infection. B. burgdorferi is the bacterium transmitted by ticks to humans to cause Lyme disease.

None of the consecutive episodes of bull's-eye rashes was linked to the same strain of the bacteria.

"We found that in every single case, the subsequent infection was new," Nadelman said.

In addition, Nadelman said all of the new infections occurred during the tick-biting season -- late spring to summer -- and all of the rashes occurred at sites that were different from the initial infection. What these findings point to, he said, is a need for tick prevention.

One physician said the new findings lend more support to his current clinical practice.

"This study helps to solidify the confidence in what we're already doing," said Dr. Bruce Hirsch, an attending physician in infectious diseases at North Shore University Hospital, in Manhasset, N.Y. He said he already treats new rashes as new infections, and avoids prolonged antibiotic use in people with Lyme disease.

Hirsch added that for some people, it can take a while to get over a Lyme disease infection, even after the bacteria have been destroyed by antibiotics.

"An infection can sometimes take a toll on the body, requiring a significant recovery period, and it uses a tremendous amount of energy to get over some infections," he said.

More information

Learn more about Lyme disease, including how to prevent it, from the U.S. Centers for Disease Control and Prevention.

SOURCES; Robert Nadelman, M.D., professor of medicine, division of infectious diseases, New York Medical College, Valhalla, N.Y.; Bruce Hirsch, M.D., attending physician, infectious diseases, North Shore University Hospital, Manhasset, N.Y.; Nov. 15, 2012, New England Journal of Medicine


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Bad strep throat? Its probably not strep, most likely viral
2. Heart Defect at Birth Signals Need to Check for Other Disorders: AHA
3. Re-Routing Spinal Cord Signals Restores Movement in Paralyzed Rats
4. Gatekeeper of brain steroid signals boosts emotional resilience to stress
5. HPV vaccine reduces infection, even in unvaccinated
6. Fish Pedicure a Recipe for Bacterial Infection, Researchers Warn
7. Study finds reformulated ER Oxycodone abuse rates are significantly lower than original ER Oxycodone
8. Month of Birth Might Help Determine MS Risk, Study Suggests
9. Study Reveals Gender Gap in Spotting Depression
10. Patients More Likely to Survive In-Hospital Cardiac Arrest Today: Study
11. Bright Light at Night Could Up Depression Risk, Mouse Study Suggests
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lyme Rash Reappearance Probably Signals New Infection, Study Says
(Date:2/26/2017)... ... February 26, 2017 , ... NuevaCare, a leading home care ... Millbrae, Belmont, and Palo Alto, is proud to announce an important upgrade to its ... look for home care close to home, and by having city-specific pages, NuevaCare is ...
(Date:2/26/2017)... , ... February 26, 2017 , ... ODH, Inc.™ ... Summit, February 27-28 at the Sheraton Pentagon City Hotel in Arlington, VA. ODH’s director ... to use behavioral health analytics to improve Medicaid population health management. , ODH will ...
(Date:2/24/2017)... ... 24, 2017 , ... HealthPostures, expert standing desk solution designer, ... built into the home office sit stand solution are bold colors, a new ... the benefits embedded in the TaskMate Go are available 24/7 through HealthPostures' online ...
(Date:2/24/2017)... ... ... An in-depth computational analysis of genetic variants implicated in both schizophrenia and ... may explain why susceptibility to one of the disorders could place individuals at lower ... the journal npj Schizophrenia. , “There is a wealth of genomic data on ...
(Date:2/24/2017)... ... ... With millions of Americans and people worldwide struggling with ... aware of our options and are empowered with strength and information throughout the ... newest edition of "Vision and Hearing" in USA Today, that will educate readers ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... Research and Markets has announced the addition of the "Dry ... offering. ... Dry eye Drugs Price Analysis and Strategies - 2016, provides drug pricing ... answers the following questions: What are the ... they positioned in the Global Dry eye market? What ...
(Date:2/24/2017)... , Feb. 24, 2017 Medical information ... to increase their self-service capabilities to manage inquiries ... (HCPs). New research from consulting leader ... have developed self-service website portals where HCPs can ... just one of many findings to emerge from ...
(Date:2/24/2017)... , Feb. 23, 2017 Report analyzes the ... provides separate comprehensive analytics for the US, Canada ... , Asia-Pacific , Latin ... forecasts are provided for the period 2015 through 2022. Also, ... data and analytics are derived from primary and secondary research. ...
Breaking Medicine Technology: