Navigation Links
Lupus more severe in patients with Southern European ancestry
Date:6/11/2008

Paris, France, Wednesday 11 June 2008: Systemic lupus erythematosus (SLE) patients with a higher percentage of ancestry from southern Europe have more severe disease manifestations, according to new research presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France.

According to the results of the research, northern European ancestry is shown to be associated with the relatively milder mucocutaneous (skin) manifestations of SLE, whereas southern European ancestry contributes to more severe manifestations of the disorder such as nephritis (inflammation of the kidneys) and increased production of specific autoantibodies (antibodies that fail to recognise and therefore attack the body's own cells, tissues or organs).

SLE is a complex autoimmune disease characterised by chronic inflammation and damage to body tissues, which occurs as a result of the production of abnormal antibodies that target and cause damage to cells of the patient's body, including immune cells. SLE has the potential to affect a variety of areas of the body, including the heart, lungs, kidneys, joints, and/or nervous system. The course of the disease is unpredictable, with periods of illness (called flares) alternating with remission. Lupus can occur at any age but is most common in women, particularly of non-European descent. Until now, the relationship between specific European ancestry and SLE severity has not been studied.

Professor Lindsey A Criswell of the University of California, San Francisco, USA, who led the study, said: "Exploring the ancestry and genetic make-up of patients in relation to their disease today helps us to better understand the complex nature of SLE and why it manifests itself differently in different people. This study shows a clear correlation between specific European ancestry and SLE disease severity and autoantibody production, which may further assist in understanding the ris
'/>"/>

Contact: Rory Berrie / Camilla Dormer
eularpressoffice@uk.cohnwolfe.com
44-077-892-70392
European League Against Rheumatism
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Blood Cancer Drug Shows Promise Against Lupus
2. Annie and Toms Race to the Altar Inspires Lupus Community
3. Lupus Live Web Chat Focuses on Medication Management
4. Lupus Community Rallies Behind Fiancee With Lupus in Race to the Altar
5. Abnormal editing of gene messages may be a cause of lupus
6. Patti LaBelle Wows Crowd at 5th Annual Lupus Foundation of America Awards Gala
7. 5th Annual World Lupus Day Philadelphians Take Part In a Global Rally of Support
8. Grammy Award Winner Patti LaBelle Is Featured Entertainer at Lupus Foundation of America Awards Gala
9. Lupus Organizations Issue International Call-to-Action to Combat Disease Affecting Five Million People
10. Lupus Foundation of America Seeks Funding Proposals for Research Studies on Childhood Lupus, Nervous System Involvement, and More
11. The Alliance for Lupus Research Announces 2008 Grantees
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... 15, 2014 Veretekk.com, Inc. announced today ... Avenue. JM Ocean Avenue has secured exclusive benefit ... automated marketing system. JM Ocean Avenue is a ... of Ocean Avenue and JM International, with partial ownership ... per year company. , “After nearly 2 decades of ...
(Date:12/15/2014)... OutMarket , a provider of marketing automation ... Sheets ,” a guide that exposes the insider secrets ... top ten social media networks. , Social media ... and customer service. It can also increase new leads ... new networks and weather constantly changing algorithms, they need ...
(Date:12/15/2014)... The increase in prevalence of disabling hearing loss in ... is contributing to the growth in the global audiological market. ... hearing loss and balance disorders are known as audiological devices. ... and amplifier. The global market is expected to grow at ... from 2014 to 2019. Some of the factors which are ...
(Date:12/15/2014)... 2014 At the leading, long-established event ... and Focus Autism will welcome scientists ... on the effects of toxins to children’s health, as ... , Luminaries such as Dr. Lucija Tomljenovic and ... esteemed, credentialed colleagues of the United States to present ...
(Date:12/15/2014)... Los Angeles, CA (PRWEB) December 15, 2014 ... power score of 3.3 out of 5. This score ... advantage with regard to negotiating prices. “Suppliers have been ... three years to 2014, largely due to rising demand,” ... buyers benefit from low price volatility. , During the ...
Breaking Medicine News(10 mins):Health News:JM Ocean Avenue secures the strategic advantages of Veretekk 2Health News:JM Ocean Avenue secures the strategic advantages of Veretekk 3Health News:JM Ocean Avenue secures the strategic advantages of Veretekk 4Health News:OutMarket Releases Cheat Sheets for Social Media Marketing 2Health News:OutMarket Releases Cheat Sheets for Social Media Marketing 3Health News:Audiological Devices Market 2019 Demand for Esthetic Hearing Aids Drives the Growth, Says a Report at ReportsnReports.com 2Health News:Audiological Devices Market 2019 Demand for Esthetic Hearing Aids Drives the Growth, Says a Report at ReportsnReports.com 3Health News:Audiological Devices Market 2019 Demand for Esthetic Hearing Aids Drives the Growth, Says a Report at ReportsnReports.com 4Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3Health News:Metal Drilling Machines Procurement Category Market Research Report Now Available from IBISWorld 2Health News:Metal Drilling Machines Procurement Category Market Research Report Now Available from IBISWorld 3
... Birner Dental Management,Services, Inc. (Nasdaq: BDMS ), ... quarterly dividend. The Company,s board of directors,has declared ... share of common,stock. The dividend is payable April ... Birner Dental Management Services, Inc. acquires, develops, ...
... gain weight rapidly after having their tonsils and adenoids ... the short-term, but over time they may relapse or ... to new research from Cincinnati Childrens Hospital Medical Center. ... in children, ranging from about 19 per 10,000 in ...
... (CVD) is the main cause of death in the European ... cost the economy 192 billion Euros annually. Many of ... nurses and allied health professionals are on the frontline of ... Europe and will be discussing new ways to assess risk, ...
... 13 MannKind,Corporation (Nasdaq: MNKD ), focused on ... today that it,will present at the Cowen and Company ... at the Marriott Copley Place Hotel in Boston, MA., ... live web cast of the,presentation in the Investor Relations ...
... Million Pledges in Support of Movement and Encourages ... Open Dialogue Within The Community, NEW ... to launch a national campaign entitled "Healing Starts With,Us." On the ... Like We,re Not Hurting, emerges a powerful movement aimed to provide,a ...
... molecule adenosine linked to priapism , Priapism (prolonged ... common in male individuals with sickle cell disease (SCD), ... cells. Priapism is considered a medical emergency because it ... tissue, which can result in erectile tissue damage and, ...
Cached Medicine News:Health News:The ABCs of childhood z's: Snoring may be chronic despite surgery 2Health News:Cardiovascular nursing: Striving for excellence in the care of cardiac patients 2Health News:The Stay Strong Foundation Launches National 'Healing Starts With US' Campaign With Celebrity Guests Denzel Washington, Ruby Dee, Mo'Nique, Terry McMillan, Rev. Al Sharpton and Others 2Health News:The Stay Strong Foundation Launches National 'Healing Starts With US' Campaign With Celebrity Guests Denzel Washington, Ruby Dee, Mo'Nique, Terry McMillan, Rev. Al Sharpton and Others 3Health News:JCI online early table of contents: March 13, 2008 2Health News:JCI online early table of contents: March 13, 2008 3Health News:JCI online early table of contents: March 13, 2008 4Health News:JCI online early table of contents: March 13, 2008 5Health News:JCI online early table of contents: March 13, 2008 6Health News:JCI online early table of contents: March 13, 2008 7
(Date:12/17/2014)... , Dec. 17, 2014  Strategic Health Services, Inc. ... solutions, today announced a strategic agreement with QualCare, Inc., a ... New Jersey regional marketplace.  This agreement will ... health and wellness solutions QualCare brings to its clients ... surrounding region. QualCare plans cover more ...
(Date:12/17/2014)... SCOTTSDALE, Ariz. , Dec. 17, 2014 /PRNewswire/ ... of state-of-the-art interactive music products, today announced that ... Ltd, a leading manufacturer and supplier of innovative ... As part of the agreement, RSL ... Facility bundled solution specifically configured for use within ...
(Date:12/17/2014)... , Dec. 17, 2014  IGI Laboratories, Inc. ... the closing of its offering of $125 million aggregate ... (the "Notes").  The Notes were offered and sold only ... the Securities Act of 1933, as amended (the "Securities ... fixed rate of 3.75% per year, payable semiannually in ...
Breaking Medicine Technology:Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 2Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 3Beamz Interactive, Inc. Signs UK Distribution Agreement with RSL Steeper Limited 2Beamz Interactive, Inc. Signs UK Distribution Agreement with RSL Steeper Limited 3IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 2IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 3IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 4
... $300,000 as Title Sponsor of ZENPEP(R) CF Cycle for Life , ... BETHESDA, Md. , May 3 Thousands of cyclists will take ... tour in 18 cities across the country to support research to find new therapies and a ... San Francisco on June 26 . , ...
... American Pacific Corporation ( APFC) ("AMPAC") ... on Thursday, May 6, 2010 , immediately after the market closes, followed ... , , , ... invites you to participate in the teleconference to discuss the financial results ...
Cached Medicine Technology:Cystic Fibrosis Foundation Launches National Cycling Series to Benefit Critical Research and Care 2Cystic Fibrosis Foundation Launches National Cycling Series to Benefit Critical Research and Care 3American Pacific to Release Financial Results and Hold Fiscal 2010 Second Quarter Investor Teleconference 2
... Coreograft PLIF Allograft System ... cortical strut designed to ... and facilitate interbody fusion. ... specially designed instrument set ...
Duet Lumbar Allografts are comprised of a raised cancellous inner core providing biomechanical properties for rapid healing. Specially designed instruments facilitate the insertion of Duet Allografts...
... Allograft is comprised of two cortical ... center. The cortical planks provide strength ... bone provides a lattice for remodeling, ... and inferior surface teeth increase the ...
... is machined from cortical bone ... graft is machined with a ... and resistance to graft migration. ... bilaterally as a good alternative ...
Medicine Products: