Navigation Links
Lupus May Be Linked to Serious Pregnancy Complication
Date:11/2/2012

FRIDAY, Nov. 2 (HealthDay News) -- A new study suggests that pregnant women with the autoimmune disease lupus may have a twofold increased risk of preeclampsia, a dangerous condition characterized by high blood pressure and protein in the urine.

Preeclampsia can lead to serious health problems such as seizure, stroke and organ failure and cause the death of the mother and/or baby.

The researchers also found that the use of disease-modifying antirheumatic drugs (DMARDs) during pregnancy was associated with a statistically insignificant increased risk of preeclampsia. These medications are used to treat lupus and other autoimmune diseases such as rheumatoid arthritis, although their use during pregnancy is rare.

The slightly higher risk associated with antirheumatic drugs could be explained by the severity of autoimmune disease among users, according to the study, which was published in the November issue of the journal Arthritis Care & Research. This class of medications includes methotrexate (brand names Rheumatrex and Trexall), hydroxychloroquine (Plaquenil, Quineprox), etanercept (Enbrel) and adalimumab (Humira).

Understanding how their use affects women with autoimmune disease is important, especially during pregnancy, lead author Kristin Palmsten, of the Harvard School of Public Health, said in a journal news release.

Palmsten and her colleagues looked at data on nearly 307,000 pregnancies among almost 225,000 women in the province of British Columbia, Canada.

"Our findings uphold previous evidence, showing that women with [lupus] had twice the risk of developing preeclampsia," she said. "The statistically non-significant increase in preeclampsia risk found for DMARDs was reduced when we more fully accounted for the potential effect of the autoimmune diseases, suggesting that the underlying disease or severity of the disease was likely contributing to the increased risk of preeclampsia among DMARD users."

Further research is needed to confirm the findings, and studies should focus on use of DMARDs and preeclampsia in women with specific autoimmune diseases, the researchers concluded.

The new study found a link between lupus and preeclampsia. It did not prove a cause-and-effect relationship.

More information

The Preeclampsia Foundation has more about preeclampsia.

-- Robert Preidt

SOURCE: Arthritis Care & Research, news release, Oct. 31, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New Guidelines Issued for Severe Lupus
2. Chronic exposure to staph bacteria may be risk factor for lupus, Mayo study finds
3. Belimumab for lupus erythematosus: Added benefit not proven
4. Women with lupus have a higher risk for preeclampsia
5. Antibiotics Linked to Retinal Detachment Risk
6. Pesticides May Be Linked to Slightly Smaller Babies, Shorter Pregnancies
7. Pharmacy Robots Linked to Bacterial Contamination of Drugs
8. 2 genetic deletions in human genome linked to the development of aggressive prostate cancer
9. Dental X-Rays May Be Linked to Benign Brain Tumors
10. In Mice, Drug Reverses Symptoms of Condition Linked to Autism
11. Huntingtons Disease Linked to Reduced Cancer Risk in Study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lupus May Be Linked to Serious Pregnancy Complication
(Date:2/26/2017)... KS (PRWEB) , ... February ... ... StaffBridge sets a new technology standard in staffing, scheduling, and reporting for ... monitor, and predict activity throughout the entire staffing process. StaffBridge technology improves ...
(Date:2/26/2017)... , ... February 26, 2017 , ... ... after receiving cognitive rehabilitation, according to a study released today at the 1st ... cognitive rehabilitation programs are proven to be effective in improving cognitive function in ...
(Date:2/25/2017)... ... February 25, 2017 , ... FCPX users now have the ability ... Film Studios. With ProSharpen Color users have total control over sharpening amount, sharpening radius, ... range. With color spectrum tools users can visually see the color range effected with ...
(Date:2/24/2017)... ... February 24, 2017 , ... Houston ... options at his office, Antoine Dental Center. Currently, patients can get single dental ... may apply, but patients can learn more about these offers by contacting Antoine ...
(Date:2/24/2017)... , ... February 24, 2017 , ... ... business development, education, networking and recognition opportunities as well as advocacy for the ... in Holmdel, NJ on February 23. The Council's Innovation Forecast event highlights ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)... STOCKHOLM , Feb 27, 2017 Period October – ... Operating result amounted to SEK -16.4 (-6.4) million ... -0.27 per share (-0.22) before and after dilution Cash flow ... ... amounted to SEK 0.4 (0.4) million Operating result amounted to ...
(Date:2/24/2017)... -- Research and Markets has announced the addition of ... Forecast to 2025" report to their offering. ... The Global Wireless Health Market ... the next decade to reach approximately $330.5 billion by 2025. ... all the given segments on global as well as regional levels ...
(Date:2/24/2017)... and Markets has announced the addition of the "Dry eye Drugs ... ... Drugs Price Analysis and Strategies - 2016, provides drug pricing data and ... following questions: What are the key drugs ... in the Global Dry eye market? What are the ...
Breaking Medicine Technology: