Navigation Links
Lupus May Be Linked to Serious Pregnancy Complication
Date:11/2/2012

FRIDAY, Nov. 2 (HealthDay News) -- A new study suggests that pregnant women with the autoimmune disease lupus may have a twofold increased risk of preeclampsia, a dangerous condition characterized by high blood pressure and protein in the urine.

Preeclampsia can lead to serious health problems such as seizure, stroke and organ failure and cause the death of the mother and/or baby.

The researchers also found that the use of disease-modifying antirheumatic drugs (DMARDs) during pregnancy was associated with a statistically insignificant increased risk of preeclampsia. These medications are used to treat lupus and other autoimmune diseases such as rheumatoid arthritis, although their use during pregnancy is rare.

The slightly higher risk associated with antirheumatic drugs could be explained by the severity of autoimmune disease among users, according to the study, which was published in the November issue of the journal Arthritis Care & Research. This class of medications includes methotrexate (brand names Rheumatrex and Trexall), hydroxychloroquine (Plaquenil, Quineprox), etanercept (Enbrel) and adalimumab (Humira).

Understanding how their use affects women with autoimmune disease is important, especially during pregnancy, lead author Kristin Palmsten, of the Harvard School of Public Health, said in a journal news release.

Palmsten and her colleagues looked at data on nearly 307,000 pregnancies among almost 225,000 women in the province of British Columbia, Canada.

"Our findings uphold previous evidence, showing that women with [lupus] had twice the risk of developing preeclampsia," she said. "The statistically non-significant increase in preeclampsia risk found for DMARDs was reduced when we more fully accounted for the potential effect of the autoimmune diseases, suggesting that the underlying disease or severity of the disease was likely contributing to the increased risk of preeclampsia among DMARD users."

Further research is needed to confirm the findings, and studies should focus on use of DMARDs and preeclampsia in women with specific autoimmune diseases, the researchers concluded.

The new study found a link between lupus and preeclampsia. It did not prove a cause-and-effect relationship.

More information

The Preeclampsia Foundation has more about preeclampsia.

-- Robert Preidt

SOURCE: Arthritis Care & Research, news release, Oct. 31, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New Guidelines Issued for Severe Lupus
2. Chronic exposure to staph bacteria may be risk factor for lupus, Mayo study finds
3. Belimumab for lupus erythematosus: Added benefit not proven
4. Women with lupus have a higher risk for preeclampsia
5. Antibiotics Linked to Retinal Detachment Risk
6. Pesticides May Be Linked to Slightly Smaller Babies, Shorter Pregnancies
7. Pharmacy Robots Linked to Bacterial Contamination of Drugs
8. 2 genetic deletions in human genome linked to the development of aggressive prostate cancer
9. Dental X-Rays May Be Linked to Benign Brain Tumors
10. In Mice, Drug Reverses Symptoms of Condition Linked to Autism
11. Huntingtons Disease Linked to Reduced Cancer Risk in Study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lupus May Be Linked to Serious Pregnancy Complication
(Date:2/24/2017)... York, NY (PRWEB) , ... February 24, 2017 , ... ... “Security needs to be a top priority because it’s not if you will be ... online safety, especially when it comes to digital health care. , Improvements in auditing ...
(Date:2/24/2017)... ... February 24, 2017 , ... With ProGlass Prism users now ... . Users have total control over position, rotation, distortion, edge softness, edge blur, chromatic ... Cut Pro X. , With ProGlass Prism users are given the tools and ...
(Date:2/24/2017)... ... ... Indiana Fiber Network (IFN) President and CEO Kelly C. Dyer recently announced that he ... of the Management Committee when IFN was originally formed in 2002 where he was ... development of the business plan. He became the first paid employee of IFN ...
(Date:2/24/2017)... , ... February 24, 2017 , ... ... Charlevoix, once again hosted their Military Wedding Giveaway, with the winning couple announced ... Castle Farms with services generously donated from local vendors: A Matter of Taste, ...
(Date:2/23/2017)... (PRWEB) , ... February 23, 2017 , ... ... organization devoted exclusively to funding innovative lymphoma research and serving the lymphoma community ... will return to the La Gorce Country Club in Miami Beach to host ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... , Südkorea, 23. Februar 2017 LG Innotek ... Sterilisationsaufgaben vorgestellt. Die Sterilisationsleistung beträgt das 1,5-fache des 45-mW-Moduls ... Strahlung im Bereich zwischen 200 und 280 nm und eignet ... Bakterien, indem es ihre DNA zerstört. Das Produkt von ... ...
(Date:2/23/2017)... 23. Februar 2017 Im Rahmen seiner ... Wirtschaftszone in der südwestlichen chinesischen Provinz Guizhou, 2017 mit dem ... Innovationsplattform aktiv an der Entwicklung einer eingebetteten Hightech-Schlüsselindustrie. ... Continue Reading ... ...
(Date:2/23/2017)... York , February 23, 2017 ... arising from increasing caseload for varicose veins in their ... the globe are prompting the adoption of endovenous laser ... on global endovenous laser therapy market, published ... aftereffects of lifestyle choices and consequences of obesity have ...
Breaking Medicine Technology: