Navigation Links
Lung Cancer May Lie Dormant for 2 Decades
Date:10/10/2014

THURSDAY, Oct. 9, 2014 (HealthDay News) -- Lung cancer can remain dormant for more than 20 years before suddenly becoming aggressive, a new study says.

Researchers analyzed lung cancers from seven patients -- including smokers, former smokers and never smokers -- and found that the initial genetic errors that cause the cancer can go undetected for many years.

This dormancy can end when new, additional genetic mistakes occur and trigger rapid cancer growth, the researchers said. During this sudden growth, different genetic errors appear in separate parts of the tumor. Each of these areas evolves differently, and every one is genetically unique, they explained.

The researchers also found that smoking causes many of the early genetic faults linked to lung cancer, but these become less important as the disease evolves. They said most of the new cancer-causing mutations are the results of a process controlled by a protein called APOBEC.

The large variety of genetic errors found within lung cancers explains why targeted treatments have had limited success against the disease, according to the Cancer Research UK scientists.

Their study was published Oct. 9 in the journal Science.

"This fascinating research highlights the need to find better ways to detect lung cancer earlier when it's still following just one evolutionary path. If we can nip the disease in the bud and treat it before it has started traveling down different evolutionary routes, we could make a real difference in helping more people survive the disease," Professor Nic Jones, chief scientist at Cancer Research UK, said in a news release from the organization.

Survival rates from lung cancer remain "devastatingly low," added study author Charles Swanton. "By understanding how it develops we've opened up the disease's evolutionary rule book in the hope that we can start to predict its next steps," Swanton said in the news release.

More information

The U.S. Centers for Disease Control and Prevention has more about lung cancer.

SOURCE: Cancer Research UK, news release, Oct. 9, 2014

--


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. New Stool Test Might Aid in Early Detection of Colon Cancer
3. Study reveals how cancer drug causes diabetic-like state
4. How a cancer drug leads to diabetes
5. You Survived Cancer: Now Pay Attention to Your Overall Health
6. New drug prevents spread of human prostate cancer cells
7. Eliminating the good cholesterol receptor may fight breast cancer
8. Taller, Heavier Women May Face Higher Ovarian Cancer Risk
9. Experimental Chemo Combo for Colon Cancer Disappoints
10. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
11. Targeted therapeutics for colon cancer to be presented at AACR meeting
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lung Cancer May Lie Dormant for 2 Decades
(Date:6/24/2019)... ... 2019 , ... Cibo Vita, Inc., makers of Nature’s Garden, NutriPops, Chocolate Orchard ... indulgence snack line at the 65th annual Summer Fancy Food Show, taking place at ... booth #5721. , The company’s expansive product portfolio features a variety of trail ...
(Date:6/20/2019)... ... , ... Access Healthcare, one of the largest providers of ... appointed as Senior Vice President of Client Services. Angel brings more than 20 ... high performing teams, and driving revenue growth for healthcare companies. , In this ...
(Date:6/19/2019)... (PRWEB) , ... June 19, ... ... from non-governmental organizations, academia, faith-based organizations, private institutions, media, and government joined ... DC to make commitments to improve universal access to water, sanitation, and ...
(Date:6/19/2019)... , ... June 19, 2019 , ... A legal-medical ... the United States, has filed class action lawsuits in 34 of the 48 ... in the class actions are an array of pharmaceutical manufacturers, distributors and retailers, all ...
(Date:6/19/2019)... ... June 19, 2019 , ... Ovation® Fertility scientists have been invited ... Reproduction and Embryology (ESHRE) Annual Meeting in Vienna, June 23-26, 2019. , Ovation’s ... consideration for both the Basic Science Award for Oral Presentation and the Fertility Society ...
Breaking Medicine News(10 mins):
(Date:6/19/2019)... ... June 19, 2019 , ... One is never too old to make dreams ... Home (LAJH). Known as a destination for Los Angeles-area seniors, LAJH has an environment ... and Mildred Moccio, it is also a point of embarkation: a place from which ...
(Date:6/19/2019)... ... June 19, 2019 , ... A new survey by The ... $376 per month on healthcare costs. If that doesn’t sound like enough of ... per month, one-in-five survey participants reported spending $1,000 per month or more. The ...
(Date:6/18/2019)... , ... June 18, 2019 , ... ... emergency medicine and hospital medicine management services, are pleased to announce the acquisition ... in Longview, Texas. , LEMA’s 34 physicians and 9 advanced practice clinicians ...
Breaking Medicine Technology: