Navigation Links
Lung Cancer Genetics Different in Black Patients: Study
Date:11/14/2008

Finding may explain why treatment and outcomes are different among races

FRIDAY, Nov. 14 (HealthDay News) -- Non-small cell lung tumors tend to have a different genetic makeup in blacks than in whites, a finding that may explain why treatment and outcomes are different among races, a new study says.

In blacks, the tumors are more likely to carry more copies of the epidermal growth factor receptor (EGFR) gene and fewer mutations of EGFR itself, according to researchers who presented their findings Nov. 13 at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology. Previous studies have shown that more copies, regardless of mutation, predict patient responses to EGFR inhibitor drugs, such as erlotinib and gefitinib, the researchers said.

Blacks with this type of lung cancer typically do not fare well, based on past studies.

"The findings of this study were surprising, since it was not expected that drug-sensitizing EGFR mutations would be so rare in this patient population," study co-author Dr. Rom Leidner, a clinical fellow in hematology/oncology at Case Western Reserve University in Cleveland, said in a news release issued by the conference organizers. "African-American patients remain underrepresented in clinical studies in oncology, and therefore our knowledge base about how to modify our treatment strategies for this patient population remains poorly defined."

The study's researchers said they hope their findings influence the design of future clinical studies and the future use of EGFR-targeted agents.

More information

The American Cancer Society has more about non-small cell lung cancer.



-- Kevin McKeever



SOURCE: American Society for
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Genetics of aging and cancer resistance
2. UCLA scientists find cell pathway driving a deadly sub-type of breast cancer
3. THE CURE FOR CANCER? Documentary Film Defies the American Medical Community's Prescribed Treatments for Cancer and Chronic Disease
4. Lung Cancer Patients Get Blamed for Their Disease
5. Saturated Fats Linked to Cancer of Small Intestine
6. Lung Cancer Alliance-California Issues Inaugural State-Specific Report Card on Lung Cancer
7. Fourth Annual EagleBank Foundation Fight Breast Cancer Golf Classic Raises Over $100,000
8. Cancer researcher receives $3.8 million award from US Department of Defense
9. Watson Announces the NDA for a 6-Month Formulation of TRELSTAR(R) Accepted for Filing by FDA for the Treatment of Advanced Prostate Cancer
10. Debiopharm Announces U.S. NDA Filing of Trelstar(R) 6-Month Formulation for Locally Advanced or Metastatic Prostate Cancer
11. Lung Cancer May Be Deadlier for Men
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lung Cancer Genetics Different in Black Patients: Study
(Date:1/22/2015)... Autocarinsurancebest.com has released a new blog post ... insurance policy . , Auto insurance quotes help many ... no longer necessary to call an agent or visit an ... on a single website: http://autocarinsurancebest.com/ . , Every business ...
(Date:1/22/2015)... 2015 A study recently published ... journal Medicine & Science in Sports & Exercise ... help reduce gastrointestinal (GI) problems associated with physical ... in the double-blind, placebo-controlled study took 10 grams ...
(Date:1/22/2015)... Four years since the release of their debut recording Love ... of Avasa & Matthew Love – the duo are pleased to ... through White Swan Records on February 24, 2015. , THE ROAD ... available to all of us to walk out of the mire ...
(Date:1/22/2015)... January 22, 2015 JJsHouse.com is a famous ... Today, the business announces its latest collection of wedding ... “The most important issue is the wedding dress on your ... in a woman’s life. Every bride wants to find the ...
(Date:1/22/2015)... USA (PRWEB) January 22, 2015 State ... statewide data management system with support from GEOSYSTEMS, a ... The new solution will leverage Hexagon Geospatial’s ERDAS ... vector data as well as point clouds and documents. ...
Breaking Medicine News(10 mins):Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 2Health News:State Forestry Institute Mecklenburg-Vorpommern, Germany Embraces Hexagon Geospatial Technology 3
... on a transporter that actually quietens the body’s natural ... potent and non-habit //forming pain killers and will help ... ,Opioid peptides are natural pain relievers with receptors – ... the body, says Dr. Vadivel Ganapathy, chair of the ...
... on animal health has declared India as free from the ... intestinal tract of cattle //. ,'This recognition of ... It is the first animal disease to be officially recognised ... from India,' agriculture ministry said in a statement Friday. ...
... changing lifestyles has led to Himachal Pradesh having one of ... to a survey //. ,The latest countrywide findings of ... Pradesh out of every 100,000 people, 195 had a mental ... carried out after 11 years. ,Kerala has the ...
... Medical School it is said that a resistant bacteria was ... patients. // Pseudomonas aeruginosa (PA) is the bacteria which secretes ... Mougous, lead author of the study published in the June ... the host may be a cancer patient with a weakened ...
... doctors’ role in interrogating detainees, but ... a role, claiming that it can lead interrogaters’ to ... of medical advice. ,Medical professionals were used by ... lot of flak from human rights groups and medical ...
... popular excuse "not tonight, I have a headache," a ... activity and says that sexual desire and migraine may ... ,In fact, migraine sufferers reported higher levels of ... according to researchers from Wake Forest University School of ...
Cached Medicine News:Health News:Transporter offers reliable clues for safer pain medicine 2Health News:Transporter offers reliable clues for safer pain medicine 3Health News:India Declared Free of Rinderpest Cattle Infection 2Health News:Treatment of Bacterial Infection Paves the Way to Treat CF Infection 2Health News:Medical Role In Interrogations Curtailed By Pentagon 2
(Date:1/23/2015)... , Jan. 23, 2015  A new analysis of ... D 2015 enrollment data shows that 81 percent of ... access and extra discounts at certain pharmacies. The findings ... "Preferred pharmacy plans are now the foundation of Medicare ...
(Date:1/23/2015)... , Jan. 23, 2015 /PRNewswire/-- Harwood Feffer LLP ( ... of directors of Advaxis, Inc. ("Advaxis" or the "Company") ... has breached its fiduciary duties to shareholders. ... an investing website reporting that Advaxis had misrepresented the ...
(Date:1/23/2015)...  Lixte Biotechnology Holdings, Inc. (OTCQB: LIXT), announced that the number ... lead compound, LB‑100, is being conducted, has been expanded from ... , M.D., the founder and President of Lixte, said that, ... single site. Accrual of patients, however, was slower than projected. ...
Breaking Medicine Technology:New Analysis: 81 Percent of Medicare Part D Seniors Choose "Preferred Pharmacy" Plans in 2015 2Harwood Feffer LLP Announces Investigation of Advaxis, Inc. 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: