Navigation Links
Lung Cancer Genetics Different in Black Patients: Study
Date:11/14/2008

Finding may explain why treatment and outcomes are different among races

FRIDAY, Nov. 14 (HealthDay News) -- Non-small cell lung tumors tend to have a different genetic makeup in blacks than in whites, a finding that may explain why treatment and outcomes are different among races, a new study says.

In blacks, the tumors are more likely to carry more copies of the epidermal growth factor receptor (EGFR) gene and fewer mutations of EGFR itself, according to researchers who presented their findings Nov. 13 at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology. Previous studies have shown that more copies, regardless of mutation, predict patient responses to EGFR inhibitor drugs, such as erlotinib and gefitinib, the researchers said.

Blacks with this type of lung cancer typically do not fare well, based on past studies.

"The findings of this study were surprising, since it was not expected that drug-sensitizing EGFR mutations would be so rare in this patient population," study co-author Dr. Rom Leidner, a clinical fellow in hematology/oncology at Case Western Reserve University in Cleveland, said in a news release issued by the conference organizers. "African-American patients remain underrepresented in clinical studies in oncology, and therefore our knowledge base about how to modify our treatment strategies for this patient population remains poorly defined."

The study's researchers said they hope their findings influence the design of future clinical studies and the future use of EGFR-targeted agents.

More information

The American Cancer Society has more about non-small cell lung cancer.



-- Kevin McKeever



SOURCE: American Society for Therapeutic Radiology and Oncology, news release, Nov. 13, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Genetics of aging and cancer resistance
2. UCLA scientists find cell pathway driving a deadly sub-type of breast cancer
3. THE CURE FOR CANCER? Documentary Film Defies the American Medical Community's Prescribed Treatments for Cancer and Chronic Disease
4. Lung Cancer Patients Get Blamed for Their Disease
5. Saturated Fats Linked to Cancer of Small Intestine
6. Lung Cancer Alliance-California Issues Inaugural State-Specific Report Card on Lung Cancer
7. Fourth Annual EagleBank Foundation Fight Breast Cancer Golf Classic Raises Over $100,000
8. Cancer researcher receives $3.8 million award from US Department of Defense
9. Watson Announces the NDA for a 6-Month Formulation of TRELSTAR(R) Accepted for Filing by FDA for the Treatment of Advanced Prostate Cancer
10. Debiopharm Announces U.S. NDA Filing of Trelstar(R) 6-Month Formulation for Locally Advanced or Metastatic Prostate Cancer
11. Lung Cancer May Be Deadlier for Men
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lung Cancer Genetics Different in Black Patients: Study
(Date:9/22/2017)... ... September 22, 2017 , ... ... and Richard Pedranti Architect (RPA), a full-service architecture firm focusing on ... Solsken Line of Model Homes . Independently, Ecocor and RPA have extensive ...
(Date:9/22/2017)... Sonora, California (PRWEB) , ... September 22, 2017 ... ... of the inaugural SABRE Safe Is Smart Scholarship Sweepstakes.,  , Molli C., a ... pursuing an MS in Educational Leadership and Administration at St. Thomas University in ...
(Date:9/22/2017)... ... September 22, 2017 , ... “Cursed with a ... obligatory tithe, and the freedom experienced when breaking free from this misconception. “Cursed ... Lysa M. Harrison. , Published by Christian Faith Publishing, Lysa M. Harrison’s new ...
(Date:9/22/2017)... ... September 22, 2017 , ... ... explores the world of Alzheimer’s. Alzheimer’s is a disease estimated to affect the ... to information published by the Alzheimer’s Association, a leading voice in the fight ...
(Date:9/22/2017)... ... ... From Home”: a moving compilation of letters that remind readers of the fact ... the creation of published author, John Allred, a passionate leader of ministry to new ... has traveled and ministered on four continents. , “It is my hope and daily ...
Breaking Medicine News(10 mins):
(Date:9/1/2017)... -- Bayer will present the latest research from across its growing ... 2017 Congress, September 8-12 in Madrid, Spain ... data on Bayer,s marketed portfolio and late-stage compounds as well ... "We value the opportunity to meet ... ESMO," said Carsten Brunn , Head of Pharmaceuticals, Americas ...
(Date:8/29/2017)... HAMPTON, Va. , Aug. 29, 2017 ivWatch, LLC, ... of peripheral IV infiltrations, announced it has been awarded an Innovative ... improvement company in the country. ... A continuous monitoring device to aid in the early detection of ... The ...
(Date:8/28/2017)... CHICAGO , Aug. 28, 2017 Hill-Rom Holdings, ... Healthcare Conference on Monday, September 11, 2017, in ... and chief executive officer, is scheduled to present at 11:05 ... can be accessed at http://ir.hill-rom.com/events.cfm . A recorded replay ... live event through December 10, 2017. ...
Breaking Medicine Technology: