Navigation Links
Lung Cancer Genetics Different in Black Patients: Study
Date:11/14/2008

Finding may explain why treatment and outcomes are different among races

FRIDAY, Nov. 14 (HealthDay News) -- Non-small cell lung tumors tend to have a different genetic makeup in blacks than in whites, a finding that may explain why treatment and outcomes are different among races, a new study says.

In blacks, the tumors are more likely to carry more copies of the epidermal growth factor receptor (EGFR) gene and fewer mutations of EGFR itself, according to researchers who presented their findings Nov. 13 at the 2008 Chicago Multidisciplinary Symposium in Thoracic Oncology. Previous studies have shown that more copies, regardless of mutation, predict patient responses to EGFR inhibitor drugs, such as erlotinib and gefitinib, the researchers said.

Blacks with this type of lung cancer typically do not fare well, based on past studies.

"The findings of this study were surprising, since it was not expected that drug-sensitizing EGFR mutations would be so rare in this patient population," study co-author Dr. Rom Leidner, a clinical fellow in hematology/oncology at Case Western Reserve University in Cleveland, said in a news release issued by the conference organizers. "African-American patients remain underrepresented in clinical studies in oncology, and therefore our knowledge base about how to modify our treatment strategies for this patient population remains poorly defined."

The study's researchers said they hope their findings influence the design of future clinical studies and the future use of EGFR-targeted agents.

More information

The American Cancer Society has more about non-small cell lung cancer.



-- Kevin McKeever



SOURCE: American Society for
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Genetics of aging and cancer resistance
2. UCLA scientists find cell pathway driving a deadly sub-type of breast cancer
3. THE CURE FOR CANCER? Documentary Film Defies the American Medical Community's Prescribed Treatments for Cancer and Chronic Disease
4. Lung Cancer Patients Get Blamed for Their Disease
5. Saturated Fats Linked to Cancer of Small Intestine
6. Lung Cancer Alliance-California Issues Inaugural State-Specific Report Card on Lung Cancer
7. Fourth Annual EagleBank Foundation Fight Breast Cancer Golf Classic Raises Over $100,000
8. Cancer researcher receives $3.8 million award from US Department of Defense
9. Watson Announces the NDA for a 6-Month Formulation of TRELSTAR(R) Accepted for Filing by FDA for the Treatment of Advanced Prostate Cancer
10. Debiopharm Announces U.S. NDA Filing of Trelstar(R) 6-Month Formulation for Locally Advanced or Metastatic Prostate Cancer
11. Lung Cancer May Be Deadlier for Men
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lung Cancer Genetics Different in Black Patients: Study
(Date:8/23/2014)... 23, 2014 Hundreds of Wright ... behalf of individuals who were allegedly harmed by ... continue to move forward in the U.S. District ... reports. According to an Order dated August 19th, ... that would allow the litigation’s first case to ...
(Date:8/23/2014)... NewYork (PRWEB) August 23, 2014 GBI ... latest research: “Critical Care Therapeutics in Major Developed Markets ... Recombinant Products to Drive Market”, which provides in-depth analysis ... France, Germany, Italy, Spain, Japan and Canada. The report ... with market forecasts to 2020. It covers critical care ...
(Date:8/23/2014)... California (PRWEB) August 23, 2014 Pixel Film ... themes, announced today the release of ProIntro Vol.3, a customizable ... a fresh and professional tile just by dragging ProIntro Vol.3 ... Studios. "ProIntro Vol.3 is a definite time saver and i ... intro pack with 30 beautifully designed titles made with Final ...
(Date:8/23/2014)... 2014 Youth substance abuse is a ... different in Houston, TX. Substance abuse can happen to ... drug and alcohol dependency in higher numbers than ever ... substance abuse, but don’t know where to find professional ... be a challenge because most treatment options are designed ...
(Date:8/23/2014)... vacation is almost over and before we know it schools ... school supplies and a new wardrobe might take precedence over ... also spend some time brushing up on bed bug prevention ... heavily populated places,” said Randy Rupert, Bed Bug Team Lead ... for bed bugs to take up residence.” , An already ...
Breaking Medicine News(10 mins):Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 2Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 3Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 4Health News:Critical Care Therapeutics in Major Developed Markets to 2020 | Researchmoz 2Health News:Critical Care Therapeutics in Major Developed Markets to 2020 | Researchmoz 3Health News:A new plugin was announced today, ProIntro Vol.3 from Pixel Film Studios for Final Cut Pro X 2Health News:New Houston Hotline Assisting Juveniles in Locating Dependable Rehabilitation Help 2Health News:Expert Advice for a Bed Bug-Free School Year 2
... TUESDAY, Dec. 29 (HealthDay News) -- Winter,s icy sidewalks and ... extra hazards for elderly people, experts say. , Falls are ... 65 in the United States. Some 1.8 million people aged ... in 2005, and 15,800 died from their injuries, according to ...
... , IRVING, Texas, Dec. 29 ... and the other Global Hotel Alliance brand members ... & Lymphoma Society (LLS). The luxury hotel brands from across ... Jason Harmon, an Omni and GHA associate who succumbed to lymphoma ...
... Dec. 29 Three, Two, One...Happy New Year! This ... kissing their way to a new Colgate® Wisp® Guinness World Records® ... U.S. will prepare for the New Year,s "Midnight Kiss" with Colgate® ... they attempt to set a new Guinness World Records record for ...
... ... global recovery and prevention campaign called Stop Drinking 411 to combat prevalent alcohol abuse...read ... Gaithersburg, ... launching a global recovery and prevention campaign called Stop Drinking 411 to combat prevalent ...
... , Dec. 29 The Coalition for Pulmonary Fibrosis (CPF) ... and awareness, even in a year plagued by the economic ... cause, no FDA-approved treatment, and no cure. , The CPF ... to build awareness of the disease throughout the country. ...
... ... its website to serve more effectively millions of people suffering from alcohol abuse ... ... Recovery (NIFAR®) has completely redesigned its website to serve more effectively millions of ...
Cached Medicine News:Health News:Caution Can Help Keep Elderly Safe During Winter 2Health News:Omni Hotels & Resorts and Global Hotel Alliance Partner for Charity 2Health News:Omni Hotels & Resorts and Global Hotel Alliance Partner for Charity 3Health News:Guinness World Records(R) Attempt For 'Most People Kissing Simultaneously' to Take Place This New Year's Eve 2Health News:Guinness World Records(R) Attempt For 'Most People Kissing Simultaneously' to Take Place This New Year's Eve 3Health News:New 'Stop Drinking 411' Campaign Promotes Alcohol Recovery and Prevention via Web Social Media 2Health News:New 'Stop Drinking 411' Campaign Promotes Alcohol Recovery and Prevention via Web Social Media 3Health News:Coalition for Pulmonary Fibrosis Celebrates Successes Despite Year of Economic Downturn 2Health News:Coalition for Pulmonary Fibrosis Celebrates Successes Despite Year of Economic Downturn 3Health News:Coalition for Pulmonary Fibrosis Celebrates Successes Despite Year of Economic Downturn 4Health News:New NIFAR Website Offers Millions a Comprehensive Resource for Alcohol Education, Recovery, and Support 2Health News:New NIFAR Website Offers Millions a Comprehensive Resource for Alcohol Education, Recovery, and Support 3
(Date:8/22/2014)... On Aug. 20, at its annual meeting in ... voted on and approved a delegate resolution opposing the ... Cannabis Corp., a leading Canadian licensed producer of medicinal ... The CMA is quite right to point out that ... material, including medicinal cannabis. While some patients, particularly those ...
(Date:8/22/2014)... Equity Research highlights Epizyme (Nasdaq: EPZM - Free Report ... PNRA - Free Report ) as the Bear of the Day. ... FOLD - Free Report ), Sanofi (NYSE: SNY - ... ). Here is a synopsis of all five stocks: ... The biotech bull market is far from over due to ...
(Date:8/22/2014)... , Aug. 22, 2014  Cannabis Science, Inc. ... formulation-based drug development and related consulting, is pleased ... international medical cannabis conference taking place at the ... , on October 22, 2014.  The multilingual ... such as researchers, health professionals, and patients, to ...
Breaking Medicine Technology:Bedrocan Canada Statement Regarding Canadian Medical Association Motion on Smoking Marijuana 2Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 2Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 3Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 4Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 5Epizyme, Panera, Amicus Therapeutics, Sanofi and Shire highlighted as Zacks Bull and Bear of the Day 6Cannabis Science, Inc. (CBIS) to Sponsor 3rd International Conference on Cannabinoids in Medicine in October 2014 in Strasbourg, France 2Cannabis Science, Inc. (CBIS) to Sponsor 3rd International Conference on Cannabinoids in Medicine in October 2014 in Strasbourg, France 3
... ARBOR, Mich., Nov. 9 Thomson Reuters ... a leading clinical surveillance solution that enables hospitals to ... improve clinical quality and reduce total cost of treatment. ... at no additional cost. , CareFocus 2.0 ...
... Nov. 9 Arcadia Resources, Inc. (NYSE Amex: ... care services under the Arcadia HealthCare(SM) brand, has appointed ... will replace Tres Lund who announced his resignation from ... http://www.newscom.com/cgi-bin/prnh/20091109/DE07521 ) , Goldsmith is the Daniel ...
Cached Medicine Technology:Thomson Reuters Clinical Surveillance Solution Offers Powerful New Functionality to Improve Clinical Quality and Reduce Costs 2Thomson Reuters Clinical Surveillance Solution Offers Powerful New Functionality to Improve Clinical Quality and Reduce Costs 3Arcadia Resources Names Stephen Goldsmith to Board of Directors 2Arcadia Resources Names Stephen Goldsmith to Board of Directors 3
PDA application providing a complete guide for the diagnosis and management of electrolyte disorders....
Information on diagnosis and management of 500 common or important medical and surgical disorders....
Product includes all 15 Lexi-Comps databases. Includes Lexi-drugs, the official reference of the American Pharmacists Association and the National Professional Society of Pharmacists....
... BD Safety Knife with BD Xstar Blade ... that protects the blade in prodedure and ... based on a grind-less process for manufacturing ... outstanding sharpness and consistency. The arch ...
Medicine Products: