Navigation Links
Lowering Dietary Fat May Help Prevent Prostate Cancer

Findings in mouse model hint of new treatment strategies for the disease

THURSDAY, May 15 (HealthDay News) -- Eating less polyunsaturated fat, the kind often found in baked and fried goods, helps prevent prostate cancer in mice, according to researchers.

The finding by University of California, Los Angeles, scientists is believed to be the first of its kind in a mouse model that closely mimics human cancer.

The fat used in the study, published in the April 15 issue of the Cancer Research, came mostly from corn oil, which is made up primarily of omega-6 fatty acids -- the polyunsaturated fat commonly found in Western diets.

Mice that ate a low-fat diet, in which just 12 percent of their calories come from fat, had a 27 percent reduced incidence of prostate cancer compared to mice who ate a more traditional Western-type diet, in which 40 percent of the calories came from fat.

Research also found that precancerous prostate cells, or those that would soon become cancer, grew much more slowly in the mice eating the low-fat diet.

"A low-fat, high-fiber diet combined with weight loss and exercise is well known to be healthy in terms of heart disease and is known to reduce the risk of heart attacks and strokes, so that would be a healthy choice to make," study senior author William Aronson, a Jonsson Cancer Center researcher, said in a prepared statement. "Whether or not it will prevent prostate cancer in humans remains to be seen."

Previous studies done in Aronson's lab showed that a low-fat diet slowed the growth of aggressive human prostate cancers in mice and helped them live longer.

Aronson found that mice on the low-fat diet had higher levels of a protein in their blood that binds to insulin during the time when the precancerous prostate lesions usually develop. Aronson believes the low-fat diet caused the increase in the binding protein, and the protein helped prevent prostate cancer from thriving.

A short-term study in men assigned either a diet high in polyunsaturated fat or a low-fat diet with fish oil supplements will now take place to further determine whether diets affect malignant and benign human prostate tissue, Aronson said.

"We're looking at specific markers and growth factors in human tissue known to be important for development and progression of prostate cancer," he said. "It's this work we hope will lead to longer term prevention strategies incorporating dietary changes."

More information

The National Cancer Institute has more about prostate cancer.

-- Kevin McKeever

SOURCE: University of California, Los Angeles, news release, May 15, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford study highlights cost-effective method of lowering heart disease risks
2. Lowering Blood Protein Wont Help Kidney Patients
3. Abbotts Investigational SIMCOR(R) Offers Comparable LDL Lowering to Simvastatin and Significantly Raises HDL and Lowers Triglycerides in Phase III Study
4. Cholesterol-lowering drug linked to sleep disruptions
5. Many Patients Stop Taking Cholesterol-Lowering Drugs
6. Amount of Exercise Key to Lowering Kids Blood Pressure
7. New Type of Cholesterol-Lowering Drug Shows Promise
8. Lowering Co-Pays on Some Drugs Help Fight Chronic Diseases
9. Cholesterol-Lowering Drugs May Ease Irregular Heartbeat
10. Cholesterol-Lowering Statins Tied to Tendon Woes
11. Study shows cholesterol-lowering power of dietitian visits
Post Your Comments:
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... “While riding ... an inventor, from Bronx, N.Y. “I thought there had to be a convenient and ... the PROTECTOR. , The PROTECTOR enables disabled individuals to safely travel during cold or ...
(Date:11/25/2015)... ... November 25, 2015 , ... "When I underwent ... bras were incredibly uncomfortable," said an inventor from Bronx, N.Y. "In order to ... the patent-pending RECOVERY BRA for added comfort and support. The bra is easier ...
(Date:11/25/2015)... ... November 25, 2015 , ... Bcureful—a ... (TSC), as well as raising public awareness of the disorder while helping to ... third donation of $35,000 to bolster progress at the Tuberous Sclerosis Complex Center ...
(Date:11/24/2015)... ... November 25, 2015 , ... Genesis Chiropractic Software helps practice ... an agreement between the practice owner and the patient that automatically manages all ... projections. Click here to learn more. , According to ...
(Date:11/24/2015)... ... November 24, 2015 , ... Young patients with a wide variety of dental ... Dr. Kedar S. Lele, who are pediatric dentists in Tucson, AZ . Unlike ... iPlus 2.0™ system causes minimal discomfort and bleeding to the patient during treatment and ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... , November 24, 2015 ... --> adds Latest Guidebook for ... of 217 pages published in November 2015 to ... online business intelligence library at . ... of the fastest growing global economies with a ...
(Date:11/24/2015)... 24, 2015  Ascendant Solutions, Inc. (Pink Sheets: ASDS ... of Directors has declared a special 1 percent stock dividend ... payable December 14, 2015, to shareholders of record December 7, ... additional shares of common stock. --> ... a strong endorsement of our confidence in Ascendant,s growth strategy ...
(Date:11/24/2015)... Nov. 24, 2015 Diplomat Pharmacy, Inc. (NYSE: DPLO) ... of Clinical Services, Education and Human Resources will be presenting ... Oncology Drugs: Health Plan Strategies for a Dynamic Market" on ... Fenrick , a consultant with the Cambridge Advisory Group, where ... The webinar will discuss the rapid growth ...
Breaking Medicine Technology: